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C5DBR1_LACTC C5DBR1_LACTC C5DCL1_LACTC C5DCL1_LACTC C5DCL3_LACTC C5DCL3_LACTC C5DCY3_LACTC C5DCY3_LACTC URA6 URA6 C5DDP8_LACTC C5DDP8_LACTC C5DEU8_LACTC C5DEU8_LACTC C5DH74_LACTC C5DH74_LACTC C5DHK5_LACTC C5DHK5_LACTC ADK1 ADK1 C5DJ36_LACTC C5DJ36_LACTC ADK2 ADK2 C5E211_LACTC C5E211_LACTC
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C5DBR1_LACTCRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (879 aa)
C5DCL1_LACTCKLTH0B03938p. (403 aa)
C5DCL3_LACTCNucleoside diphosphate kinase. (153 aa)
C5DCY3_LACTCKLTH0B06776p. (335 aa)
URA6Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (282 aa)
C5DDP8_LACTCKLTH0C02728p. (214 aa)
C5DEU8_LACTCRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (867 aa)
C5DH74_LACTCCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (576 aa)
C5DHK5_LACTCKLTH0E05038p. (156 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (227 aa)
C5DJ36_LACTCKLTH0F13178p; Belongs to the GDA1/CD39 NTPase family. (658 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (225 aa)
C5E211_LACTCAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (214 aa)
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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