STRINGSTRING
C5DM08_LACTC C5DM08_LACTC C5DMR9_LACTC C5DMR9_LACTC C5DN85_LACTC C5DN85_LACTC C5DND8_LACTC C5DND8_LACTC C5DNF6_LACTC C5DNF6_LACTC C5DNH3_LACTC C5DNH3_LACTC C5E275_LACTC C5E275_LACTC C5E2P9_LACTC C5E2P9_LACTC C5DKF1_LACTC C5DKF1_LACTC C5DKA6_LACTC C5DKA6_LACTC C5DJU1_LACTC C5DJU1_LACTC KAE1 KAE1 C5DHY3_LACTC C5DHY3_LACTC C5DFV4_LACTC C5DFV4_LACTC PIF1 PIF1 C5DFG0_LACTC C5DFG0_LACTC C5DFD0_LACTC C5DFD0_LACTC C5DE79_LACTC C5DE79_LACTC C5DE73_LACTC C5DE73_LACTC C5DDD6_LACTC C5DDD6_LACTC C5DDD3_LACTC C5DDD3_LACTC C5DD76_LACTC C5DD76_LACTC C5DBJ2_LACTC C5DBJ2_LACTC C5DKG1_LACTC C5DKG1_LACTC C5DL97_LACTC C5DL97_LACTC C5DM01_LACTC C5DM01_LACTC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C5DM08_LACTCKLTH0G05016p; Belongs to the CGI121/TPRKB family. (154 aa)
C5DMR9_LACTCKLTH0G11132p. (1339 aa)
C5DN85_LACTCKLTH0G14960p. (417 aa)
C5DND8_LACTCKLTH0G16148p. (478 aa)
C5DNF6_LACTCKLTH0G16566p. (203 aa)
C5DNH3_LACTCKLTH0G17028p. (1000 aa)
C5E275_LACTCKLTH0H02706p. (1403 aa)
C5E2P9_LACTCKLTH0H06732p; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
C5DKF1_LACTCKLTH0F04158p. (132 aa)
C5DKA6_LACTCKLTH0F03058p. (1298 aa)
C5DJU1_LACTCKLTH0F19118p. (278 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (384 aa)
C5DHY3_LACTCReplication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (624 aa)
C5DFV4_LACTCKLTH0D00132p. (1258 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (899 aa)
C5DFG0_LACTCE3 ubiquitin protein ligase. (663 aa)
C5DFD0_LACTCKLTH0D14124p. (213 aa)
C5DE79_LACTCKLTH0C06974p. (114 aa)
C5DE73_LACTCDNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (381 aa)
C5DDD6_LACTCKLTH0B10428p. (1258 aa)
C5DDD3_LACTCKLTH0B10318p. (1548 aa)
C5DD76_LACTCKLTH0B08954p. (265 aa)
C5DBJ2_LACTCKLTH0A03080p. (228 aa)
C5DKG1_LACTCKLTH0F04400p. (116 aa)
C5DL97_LACTCKLTH0F11198p; Belongs to the PI3/PI4-kinase family. (2360 aa)
C5DM01_LACTCKLTH0G04862p. (479 aa)
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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