STRINGSTRING
C5DBM0_LACTC C5DBM0_LACTC C5E3S9_LACTC C5E3S9_LACTC C5E3G9_LACTC C5E3G9_LACTC C5E3E6_LACTC C5E3E6_LACTC C5E3B2_LACTC C5E3B2_LACTC PIM1 PIM1 C5E2V2_LACTC C5E2V2_LACTC C5E2N4_LACTC C5E2N4_LACTC C5E2B2_LACTC C5E2B2_LACTC C5E2A2_LACTC C5E2A2_LACTC C5E293_LACTC C5E293_LACTC C5E261_LACTC C5E261_LACTC C5DNS5_LACTC C5DNS5_LACTC C5DNM4_LACTC C5DNM4_LACTC C5DNL1_LACTC C5DNL1_LACTC C5DNG2_LACTC C5DNG2_LACTC C5DND8_LACTC C5DND8_LACTC C5DN65_LACTC C5DN65_LACTC C5DN43_LACTC C5DN43_LACTC C5DMZ4_LACTC C5DMZ4_LACTC C5DMY7_LACTC C5DMY7_LACTC C5DMB7_LACTC C5DMB7_LACTC RRM3 RRM3 C5DLQ6_LACTC C5DLQ6_LACTC C5DLK6_LACTC C5DLK6_LACTC C5DKY6_LACTC C5DKY6_LACTC C5DKL6_LACTC C5DKL6_LACTC C5DKD6_LACTC C5DKD6_LACTC C5DK60_LACTC C5DK60_LACTC C5DJW5_LACTC C5DJW5_LACTC C5DJQ5_LACTC C5DJQ5_LACTC C5DJG4_LACTC C5DJG4_LACTC C5DJE3_LACTC C5DJE3_LACTC C5DJ66_LACTC C5DJ66_LACTC C5DJ60_LACTC C5DJ60_LACTC C5DIW9_LACTC C5DIW9_LACTC C5DIS0_LACTC C5DIS0_LACTC C5DIP8_LACTC C5DIP8_LACTC C5DIJ2_LACTC C5DIJ2_LACTC C5DIH5_LACTC C5DIH5_LACTC MCM7 MCM7 C5DI28_LACTC C5DI28_LACTC C5DHQ4_LACTC C5DHQ4_LACTC C5DHP5_LACTC C5DHP5_LACTC C5DH87_LACTC C5DH87_LACTC C5DGJ7_LACTC C5DGJ7_LACTC C5DGJ4_LACTC C5DGJ4_LACTC C5DGH7_LACTC C5DGH7_LACTC C5DGA9_LACTC C5DGA9_LACTC C5DFM2_LACTC C5DFM2_LACTC PIF1 PIF1 C5DFI0_LACTC C5DFI0_LACTC C5DFF1_LACTC C5DFF1_LACTC C5DF39_LACTC C5DF39_LACTC C5DEZ0_LACTC C5DEZ0_LACTC C5DEW4_LACTC C5DEW4_LACTC C5DES1_LACTC C5DES1_LACTC C5DEK0_LACTC C5DEK0_LACTC C5DEH3_LACTC C5DEH3_LACTC C5DE73_LACTC C5DE73_LACTC C5DE25_LACTC C5DE25_LACTC C5DDS9_LACTC C5DDS9_LACTC C5DDP6_LACTC C5DDP6_LACTC C5DDN5_LACTC C5DDN5_LACTC C5DDG3_LACTC C5DDG3_LACTC C5DDB0_LACTC C5DDB0_LACTC C5DDA0_LACTC C5DDA0_LACTC C5DD87_LACTC C5DD87_LACTC C5DD84_LACTC C5DD84_LACTC C5DD39_LACTC C5DD39_LACTC C5DC90_LACTC C5DC90_LACTC C5DC66_LACTC C5DC66_LACTC C5DBU0_LACTC C5DBU0_LACTC C5DBE4_LACTC C5DBE4_LACTC C5DBD0_LACTC C5DBD0_LACTC C5DBA6_LACTC C5DBA6_LACTC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C5DBM0_LACTCKLTH0A03696p; Belongs to the AAA ATPase family. (781 aa)
C5E3S9_LACTCKLTH0H16038p. (1649 aa)
C5E3G9_LACTCKLTH0H13442p. (752 aa)
C5E3E6_LACTCKLTH0H12760p. (1020 aa)
C5E3B2_LACTCKLTH0H11902p. (1044 aa)
PIM1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1105 aa)
C5E2V2_LACTCKLTH0H07942p. (528 aa)
C5E2N4_LACTCKLTH0H06380p. (508 aa)
C5E2B2_LACTCKLTH0H03542p; Belongs to the peptidase S16 family. (989 aa)
C5E2A2_LACTCKLTH0H03300p. (1176 aa)
C5E293_LACTCRuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (470 aa)
C5E261_LACTCKLTH0H02398p. (618 aa)
C5DNS5_LACTCKLTH0G19448p; Belongs to the ABC transporter superfamily. (1486 aa)
C5DNM4_LACTCKLTH0G18326p. (269 aa)
C5DNL1_LACTCKLTH0G17930p; Belongs to the AAA ATPase family. (358 aa)
C5DNG2_LACTCKLTH0G16698p; Belongs to the AAA ATPase family. (455 aa)
C5DND8_LACTCKLTH0G16148p. (478 aa)
C5DN65_LACTCKLTH0G14520p. (608 aa)
C5DN43_LACTCKLTH0G14014p; Belongs to the RecA family. (333 aa)
C5DMZ4_LACTCMidasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4928 aa)
C5DMY7_LACTCKLTH0G12716p. (1500 aa)
C5DMB7_LACTCKLTH0G07524p; Belongs to the AAA ATPase family. (445 aa)
RRM3ATP-dependent DNA helicase RRM3; 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein- DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G- quadruplex (G4) unwindi [...] (693 aa)
C5DLQ6_LACTCKLTH0G02662p; Belongs to the AAA ATPase family. (425 aa)
C5DLK6_LACTCKLTH0G01452p. (607 aa)
C5DKY6_LACTCRuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (459 aa)
C5DKL6_LACTCKLTH0F05720p. (4108 aa)
C5DKD6_LACTCCell division control protein; Belongs to the CDC6/cdc18 family. (499 aa)
C5DK60_LACTCKLTH0F02024p. (734 aa)
C5DJW5_LACTCKLTH0F19646p. (1044 aa)
C5DJQ5_LACTCATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (508 aa)
C5DJG4_LACTCKLTH0F16214p; Belongs to the AAA ATPase family. (434 aa)
C5DJE3_LACTCKLTH0F15730p; Belongs to the AAA ATPase family. (450 aa)
C5DJ66_LACTCKLTH0F13904p. (739 aa)
C5DJ60_LACTCKLTH0F13772p. (1114 aa)
C5DIW9_LACTCKLTH0E15796p. (1247 aa)
C5DIS0_LACTCKLTH0E14696p. (384 aa)
C5DIP8_LACTCKLTH0E14190p. (763 aa)
C5DIJ2_LACTCKLTH0E12936p; Belongs to the AAA ATPase family. (544 aa)
C5DIH5_LACTCKLTH0E12562p. (715 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (828 aa)
C5DI28_LACTCKLTH0E09218p. (1253 aa)
C5DHQ4_LACTCKLTH0E06204p; Belongs to the ClpA/ClpB family. (907 aa)
C5DHP5_LACTCKLTH0E06006p; Belongs to the AAA ATPase family. (819 aa)
C5DH87_LACTCKLTH0E02200p; Belongs to the ClpA/ClpB family. (780 aa)
C5DGJ7_LACTCKLTH0D05852p. (702 aa)
C5DGJ4_LACTCKLTH0D05786p. (982 aa)
C5DGH7_LACTCKLTH0D05412p. (813 aa)
C5DGA9_LACTCKLTH0D03806p; Belongs to the AAA ATPase family. (405 aa)
C5DFM2_LACTCOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (939 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (899 aa)
C5DFI0_LACTCKLTH0D15246p. (798 aa)
C5DFF1_LACTCKLTH0D14586p. (774 aa)
C5DF39_LACTCKLTH0D11990p; Belongs to the AAA ATPase family. (433 aa)
C5DEZ0_LACTCKLTH0D10890p. (830 aa)
C5DEW4_LACTCReplication factor C subunit 1. (864 aa)
C5DES1_LACTCKLTH0C11616p. (740 aa)
C5DEK0_LACTCKLTH0C09900p. (322 aa)
C5DEH3_LACTCKLTH0C09240p. (1546 aa)
C5DE73_LACTCDNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (381 aa)
C5DE25_LACTCKLTH0C05742p. (744 aa)
C5DDS9_LACTCDNA helicase; Belongs to the MCM family. (994 aa)
C5DDP6_LACTCKLTH0C02684p. (1019 aa)
C5DDN5_LACTCKLTH0C02442p. (356 aa)
C5DDG3_LACTCKLTH0C00770p. (659 aa)
C5DDB0_LACTCKLTH0B09724p. (1486 aa)
C5DDA0_LACTCKLTH0B09482p. (694 aa)
C5DD87_LACTCKLTH0B09196p. (1954 aa)
C5DD84_LACTCKLTH0B09130p. (1333 aa)
C5DD39_LACTCKLTH0B08052p. (536 aa)
C5DC90_LACTCKLTH0B01100p. (1298 aa)
C5DC66_LACTCKLTH0B00396p. (1507 aa)
C5DBU0_LACTCKLTH0A05324p; Belongs to the AAA ATPase family. (832 aa)
C5DBE4_LACTCKLTH0A01914p; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1499 aa)
C5DBD0_LACTCKLTH0A01540p. (328 aa)
C5DBA6_LACTCKLTH0A00968p; Belongs to the AAA ATPase family. (427 aa)
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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