(19 nodes) Lysine degradation network (Lachancea thermotolerans)

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Predicted Interactions

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Your Input:
	C5DBI9_LACTC	Dihydrolipoyl dehydrogenase. (498 aa)
	C5DBR6_LACTC	KLTH0A04796p; Belongs to the aldehyde dehydrogenase family. (517 aa)
	C5DC40_LACTC	KLTH0A07590p. (446 aa)
	C5DCR8_LACTC	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (986 aa)
	C5DDF5_LACTC	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (372 aa)
	C5DF23_LACTC	KLTH0D11638p. (353 aa)
	C5DFX3_LACTC	KLTH0D00682p; Belongs to the aldehyde dehydrogenase family. (522 aa)
	C5DGE1_LACTC	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (523 aa)
	C5DIB3_LACTC	KLTH0E11154p; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	C5DIF9_LACTC	KLTH0E12210p; Belongs to the aldehyde dehydrogenase family. (526 aa)
	C5DJH1_LACTC	KLTH0F16390p. (587 aa)
	C5DKG6_LACTC	KLTH0F04510p; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (686 aa)
	C5DL36_LACTC	KLTH0F09658p; Belongs to the aldehyde dehydrogenase family. (503 aa)
	C5DL37_LACTC	KLTH0F09680p; Belongs to the aldehyde dehydrogenase family. (502 aa)
	C5DLY1_LACTC	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (587 aa)
	C5DMW4_LACTC	KLTH0G12188p. (441 aa)
	C5DND7_LACTC	Succinate-semialdehyde dehydrogenase. (495 aa)
	C5E2W1_LACTC	KLTH0H08162p; Belongs to the aldehyde dehydrogenase family. (506 aa)
	C5E3H3_LACTC	KLTH0H13574p. (410 aa)

Your Current Organism:

Lachancea thermotolerans

NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5DBI9_LACTC	C5DGE1_LACTC	C5DBI9	C5DGE1	Dihydrolipoyl dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.428
C5DBI9_LACTC	C5DMW4_LACTC	C5DBI9	C5DMW4	Dihydrolipoyl dehydrogenase.	KLTH0G12188p.	0.999
C5DC40_LACTC	C5DDF5_LACTC	C5DC40	C5DDF5	KLTH0A07590p.	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	0.978
C5DCR8_LACTC	C5DF23_LACTC	C5DCR8	C5DF23	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	KLTH0D11638p.	0.948
C5DCR8_LACTC	C5DJH1_LACTC	C5DCR8	C5DJH1	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	KLTH0F16390p.	0.904
C5DCR8_LACTC	C5DKG6_LACTC	C5DCR8	C5DKG6	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	KLTH0F04510p; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.977
C5DCR8_LACTC	C5DLY1_LACTC	C5DCR8	C5DLY1	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.972
C5DDF5_LACTC	C5DC40_LACTC	C5DDF5	C5DC40	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.	KLTH0A07590p.	0.978
C5DF23_LACTC	C5DCR8_LACTC	C5DF23	C5DCR8	KLTH0D11638p.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.948
C5DF23_LACTC	C5DJH1_LACTC	C5DF23	C5DJH1	KLTH0D11638p.	KLTH0F16390p.	0.915
C5DF23_LACTC	C5DKG6_LACTC	C5DF23	C5DKG6	KLTH0D11638p.	KLTH0F04510p; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.924
C5DF23_LACTC	C5DLY1_LACTC	C5DF23	C5DLY1	KLTH0D11638p.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.933
C5DGE1_LACTC	C5DBI9_LACTC	C5DGE1	C5DBI9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Dihydrolipoyl dehydrogenase.	0.428
C5DGE1_LACTC	C5DIB3_LACTC	C5DGE1	C5DIB3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	KLTH0E11154p; Belongs to the thiolase-like superfamily. Thiolase family.	0.564
C5DGE1_LACTC	C5DMW4_LACTC	C5DGE1	C5DMW4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	KLTH0G12188p.	0.521
C5DIB3_LACTC	C5DGE1_LACTC	C5DIB3	C5DGE1	KLTH0E11154p; Belongs to the thiolase-like superfamily. Thiolase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.564
C5DIB3_LACTC	C5DMW4_LACTC	C5DIB3	C5DMW4	KLTH0E11154p; Belongs to the thiolase-like superfamily. Thiolase family.	KLTH0G12188p.	0.842
C5DJH1_LACTC	C5DCR8_LACTC	C5DJH1	C5DCR8	KLTH0F16390p.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.904
C5DJH1_LACTC	C5DF23_LACTC	C5DJH1	C5DF23	KLTH0F16390p.	KLTH0D11638p.	0.915
C5DJH1_LACTC	C5DKG6_LACTC	C5DJH1	C5DKG6	KLTH0F16390p.	KLTH0F04510p; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.905