(38 nodes) Peroxisome network (Lachancea thermotolerans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C5DBB5_LACTC	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (187 aa)
	C5DBH9_LACTC	KLTH0A02772p. (383 aa)
	C5DCP8_LACTC	KLTH0B04818p. (380 aa)
	C5DD21_LACTC	KLTH0B07656p. (300 aa)
	C5DDP6_LACTC	KLTH0C02684p. (1019 aa)
	C5DEZ0_LACTC	KLTH0D10890p. (830 aa)
	C5DF50_LACTC	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (415 aa)
	C5DFE1_LACTC	KLTH0D14366p. (308 aa)
	C5DFE6_LACTC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (420 aa)
	C5DFI0_LACTC	KLTH0D15246p. (798 aa)
	C5DGT8_LACTC	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (384 aa)
	C5DH19_LACTC	KLTH0E00682p; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	C5DH73_LACTC	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	C5DH77_LACTC	KLTH0E01980p. (252 aa)
	C5DH96_LACTC	KLTH0E02464p. (329 aa)
	C5DHA5_LACTC	KLTH0E02684p. (306 aa)
	C5DHE7_LACTC	KLTH0E03762p. (464 aa)
	C5DIA3_LACTC	KLTH0E10934p. (568 aa)
	C5DID0_LACTC	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (511 aa)
	C5DIN6_LACTC	KLTH0E13926p. (696 aa)
	C5DJ63_LACTC	KLTH0F13838p. (748 aa)
	C5DJC9_LACTC	KLTH0F15422p; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)
	C5DJW5_LACTC	KLTH0F19646p. (1044 aa)
	C5DJX1_LACTC	KLTH0F19778p. (221 aa)
	C5DKB8_LACTC	KLTH0F03322p. (254 aa)
	C5DLD8_LACTC	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
	C5DLM7_LACTC	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (738 aa)
	C5DLT4_LACTC	KLTH0G03300p; Belongs to the carnitine/choline acetyltransferase family. (649 aa)
	C5DM16_LACTC	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (228 aa)
	C5DMR7_LACTC	KLTH0G11088p. (332 aa)
	C5DMX5_LACTC	KLTH0G12430p. (367 aa)
	C5DN92_LACTC	KLTH0G15114p. (278 aa)
	C5DNN3_LACTC	KLTH0G18524p. (370 aa)
	C5E2D9_LACTC	KLTH0H04136p. (360 aa)
	C5E3A3_LACTC	KLTH0H11660p; Belongs to the peroxisomal membrane protein PXMP2/4 family. (200 aa)
	C5E3B7_LACTC	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
	C5E3F9_LACTC	KLTH0H13090p. (365 aa)
	C5E3J6_LACTC	KLTH0H14102p; Belongs to the TPP enzyme family. (551 aa)

Your Current Organism:

Lachancea thermotolerans

NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5DBB5_LACTC	C5DH73_LACTC	C5DBB5	C5DH73	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.656
C5DBB5_LACTC	C5DH77_LACTC	C5DBB5	C5DH77	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	KLTH0E01980p.	0.499
C5DBB5_LACTC	C5DHA5_LACTC	C5DBB5	C5DHA5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	KLTH0E02684p.	0.499
C5DBB5_LACTC	C5DM16_LACTC	C5DBB5	C5DM16	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.605
C5DBH9_LACTC	C5DCP8_LACTC	C5DBH9	C5DCP8	KLTH0A02772p.	KLTH0B04818p.	0.570
C5DBH9_LACTC	C5DGT8_LACTC	C5DBH9	C5DGT8	KLTH0A02772p.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.563
C5DBH9_LACTC	C5DH96_LACTC	C5DBH9	C5DH96	KLTH0A02772p.	KLTH0E02464p.	0.570
C5DBH9_LACTC	C5DIA3_LACTC	C5DBH9	C5DIA3	KLTH0A02772p.	KLTH0E10934p.	0.626
C5DBH9_LACTC	C5DMR7_LACTC	C5DBH9	C5DMR7	KLTH0A02772p.	KLTH0G11088p.	0.556
C5DBH9_LACTC	C5DNN3_LACTC	C5DBH9	C5DNN3	KLTH0A02772p.	KLTH0G18524p.	0.944
C5DBH9_LACTC	C5E3F9_LACTC	C5DBH9	C5E3F9	KLTH0A02772p.	KLTH0H13090p.	0.915
C5DCP8_LACTC	C5DBH9_LACTC	C5DCP8	C5DBH9	KLTH0B04818p.	KLTH0A02772p.	0.570
C5DCP8_LACTC	C5DDP6_LACTC	C5DCP8	C5DDP6	KLTH0B04818p.	KLTH0C02684p.	0.896
C5DCP8_LACTC	C5DEZ0_LACTC	C5DCP8	C5DEZ0	KLTH0B04818p.	KLTH0D10890p.	0.675
C5DCP8_LACTC	C5DFE1_LACTC	C5DCP8	C5DFE1	KLTH0B04818p.	KLTH0D14366p.	0.997
C5DCP8_LACTC	C5DFE6_LACTC	C5DCP8	C5DFE6	KLTH0B04818p.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.568
C5DCP8_LACTC	C5DFI0_LACTC	C5DCP8	C5DFI0	KLTH0B04818p.	KLTH0D15246p.	0.675
C5DCP8_LACTC	C5DGT8_LACTC	C5DCP8	C5DGT8	KLTH0B04818p.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.936
C5DCP8_LACTC	C5DH19_LACTC	C5DCP8	C5DH19	KLTH0B04818p.	KLTH0E00682p; Belongs to the thiolase-like superfamily. Thiolase family.	0.783
C5DCP8_LACTC	C5DH96_LACTC	C5DCP8	C5DH96	KLTH0B04818p.	KLTH0E02464p.	0.920