(29 nodes) Mixed, incl. Butanoate metabolism, and Aldehyde dehydrogenase domain network (Millerozyma farinosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Piso0_004743	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (162 aa)
	Piso0_005255-2	Piso0_005255 protein. (2304 aa)
	Piso0_005289-2	Succinate-semialdehyde dehydrogenase. (511 aa)
	Piso0_003782	Acetyl-coenzyme A synthetase. (679 aa)
	Piso0_004096	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (564 aa)
	Piso0_003759	Piso0_003759 protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (438 aa)
	Piso0_004354	Acetyl-coenzyme A synthetase. (671 aa)
	Piso0_004654	Piso0_004654 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (470 aa)
	Piso0_004012	Piso0_004012 protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	Piso0_004043	Piso0_004043 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (509 aa)
	Piso0_002198	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (448 aa)
	Piso0_002511	Piso0_002511 protein. (543 aa)
	Piso0_002198-2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (448 aa)
	Piso0_002511-2	Piso0_002511 protein. (543 aa)
	Piso0_002686-2	Piso0_002686 protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
	Piso0_002724-2	Piso0_002724 protein. (313 aa)
	Piso0_003640	Piso0_003640 protein; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	Piso0_003268	Piso0_003268 protein. (523 aa)
	Piso0_002969	Succinate-semialdehyde dehydrogenase. (492 aa)
	Piso0_001508	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa)
	Piso0_001634	Piso0_001634 protein. (895 aa)
	Piso0_001351	Malate synthase; Belongs to the malate synthase family. (556 aa)
	Piso0_001508-2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa)
	Piso0_001551-2	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (324 aa)
	Piso0_001147	Piso0_001147 protein. (525 aa)
	Piso0_001089	Piso0_001089 protein; Belongs to the aldehyde dehydrogenase family. (522 aa)
	Piso0_000240	Piso0_000240 protein. (1821 aa)
	Piso0_000053-2	Piso0_000053 protein. (276 aa)
	Piso0_000240-2	Piso0_000240 protein. (1821 aa)

Your Current Organism:

Millerozyma farinosa

NCBI taxonomy Id: 559304
Other names: M. farinosa CBS 7064, Millerozyma farinosa CBS 7064, Pichia farinosa CBS 7064

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Piso0_000053-2	Piso0_000240	G8YUE4	G8YTG1	Piso0_000053 protein.	Piso0_000240 protein.	0.881
Piso0_000053-2	Piso0_000240-2	G8YUE4	G8YUW7	Piso0_000053 protein.	Piso0_000240 protein.	0.881
Piso0_000053-2	Piso0_001089	G8YUE4	G8YQW7	Piso0_000053 protein.	Piso0_001089 protein; Belongs to the aldehyde dehydrogenase family.	0.565
Piso0_000053-2	Piso0_001147	G8YUE4	G8YPD7	Piso0_000053 protein.	Piso0_001147 protein.	0.800
Piso0_000053-2	Piso0_001351	G8YUE4	G8YMI6	Piso0_000053 protein.	Malate synthase; Belongs to the malate synthase family.	0.574
Piso0_000053-2	Piso0_001508	G8YUE4	G8YKZ5	Piso0_000053 protein.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.565
Piso0_000053-2	Piso0_001508-2	G8YUE4	G8YNC7	Piso0_000053 protein.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.565
Piso0_000053-2	Piso0_001551-2	G8YUE4	G8YNG8	Piso0_000053 protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.548
Piso0_000053-2	Piso0_001634	G8YUE4	G8YLB3	Piso0_000053 protein.	Piso0_001634 protein.	0.451
Piso0_000053-2	Piso0_002198	G8YUE4	G8YBZ0	Piso0_000053 protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.755
Piso0_000053-2	Piso0_002198-2	G8YUE4	G8YEE0	Piso0_000053 protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.755
Piso0_000053-2	Piso0_002511	G8YUE4	G8YCT5	Piso0_000053 protein.	Piso0_002511 protein.	0.770
Piso0_000053-2	Piso0_002511-2	G8YUE4	G8YF86	Piso0_000053 protein.	Piso0_002511 protein.	0.770
Piso0_000053-2	Piso0_002686-2	G8YUE4	G8YFP8	Piso0_000053 protein.	Piso0_002686 protein; Belongs to the aldehyde dehydrogenase family.	0.565
Piso0_000053-2	Piso0_002724-2	G8YUE4	G8YFT2	Piso0_000053 protein.	Piso0_002724 protein.	0.601
Piso0_000053-2	Piso0_002969	G8YUE4	G8YJZ7	Piso0_000053 protein.	Succinate-semialdehyde dehydrogenase.	0.565
Piso0_000053-2	Piso0_003268	G8YUE4	G8YHM9	Piso0_000053 protein.	Piso0_003268 protein.	0.821
Piso0_000053-2	Piso0_003640	G8YUE4	G8YGG9	Piso0_000053 protein.	Piso0_003640 protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.987
Piso0_000053-2	Piso0_003759	G8YUE4	G8Y881	Piso0_000053 protein.	Piso0_003759 protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.770
Piso0_000053-2	Piso0_003782	G8YUE4	G8Y6L1	Piso0_000053 protein.	Acetyl-coenzyme A synthetase.	0.818