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| | Piso0_000617 | Piso0_000617 protein. (308 aa) |
| | Piso0_001551-2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (324 aa) |
| | Piso0_001527-2 | Piso0_001527 protein. (436 aa) |
| | Piso0_001514-2 | Piso0_001514 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (422 aa) |
| | Piso0_001490-2 | Piso0_001490 protein. (581 aa) |
| | Piso0_001463-2 | DNA ligase. (759 aa) |
| | Piso0_001396-2 | Piso0_001396 protein. (351 aa) |
| | Piso0_001378-2 | Piso0_001378 protein. (2206 aa) |
| | Piso0_001306-2 | Piso0_001306 protein. (558 aa) |
| | Piso0_001238-2 | Piso0_001238 protein. (693 aa) |
| | Piso0_001306 | Piso0_001306 protein. (558 aa) |
| | Piso0_002035-2 | Piso0_002035 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (519 aa) |
| | Piso0_001910-2 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (716 aa) |
| | Piso0_001838 | Piso0_001838 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1086 aa) |
| | Piso0_001732 | Tyrosine--tRNA ligase. (515 aa) |
| | Piso0_001615 | Piso0_001615 protein. (545 aa) |
| | Piso0_001551 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (324 aa) |
| | Piso0_001527 | Piso0_001527 protein. (436 aa) |
| | Piso0_001514 | Piso0_001514 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (422 aa) |
| | Piso0_001490 | Piso0_001490 protein. (581 aa) |
| | Piso0_001463 | DNA ligase. (759 aa) |
| | Piso0_001396 | Piso0_001396 protein. (351 aa) |
| | Piso0_001378 | Piso0_001378 protein. (2206 aa) |
| | Piso0_003184 | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (300 aa) |
| | Piso0_003080 | Piso0_003080 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa) |
| | Piso0_003069 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (575 aa) |
| | Piso0_002974 | Piso0_002974 protein. (730 aa) |
| | Piso0_003531 | Piso0_003531 protein. (683 aa) |
| | Piso0_003416 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (428 aa) |
| | Piso0_003355 | ATP synthase subunit gamma. (286 aa) |
| | Piso0_003533 | Piso0_003533 protein. (508 aa) |
| | Piso0_003530 | Piso0_003530 protein. (552 aa) |
| | Piso0_003379 | Piso0_003379 protein. (429 aa) |
| | Piso0_003343 | Piso0_003343 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (987 aa) |
| | Piso0_003235 | Adenylyltransferase and sulfurtransferase Piso0_003235; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. [...] (447 aa) |
| | Piso0_003221 | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. (591 aa) |
| | Piso0_002992 | Piso0_002992 protein. (573 aa) |
| | Piso0_003646 | Piso0_003646 protein. (989 aa) |
| | Piso0_002874-2 | Piso0_002874 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa) |
| | Piso0_002866-2 | Piso0_002866 protein. (495 aa) |
| | Piso0_002738-2 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (425 aa) |
| | Piso0_002728-2 | Piso0_002728 protein. (946 aa) |
| | Piso0_002724-2 | Piso0_002724 protein. (313 aa) |
| | Piso0_002721-2 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (650 aa) |
| | Piso0_002692-2 | Piso0_002692 protein. (1347 aa) |
| | Piso0_002653-2 | Lysine--tRNA ligase. (589 aa) |
| | Piso0_002624-2 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (503 aa) |
| | Piso0_002532-2 | Tyrosine--tRNA ligase. (399 aa) |
| | Piso0_001615-2 | Piso0_001615 protein. (545 aa) |
| | Piso0_002346-2 | Piso0_002346 protein. (655 aa) |
| | Piso0_002263-2 | Piso0_002263 protein; Belongs to the ubiquitin-activating E1 family. (1021 aa) |
| | Piso0_002228-2 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (960 aa) |
| | Piso0_002163-2 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (519 aa) |
| | Piso0_002141-2 | tRNA ligase. (835 aa) |
| | Piso0_002109-2 | Piso0_002109 protein. (676 aa) |
| | Piso0_001238 | Piso0_001238 protein. (687 aa) |
| | Piso0_002874 | Piso0_002874 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa) |
| | Piso0_002866 | Piso0_002866 protein. (495 aa) |
| | Piso0_002738 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (425 aa) |
| | Piso0_002728 | Piso0_002728 protein. (946 aa) |
| | Piso0_002724 | Piso0_002724 protein. (313 aa) |
| | Piso0_002721 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (650 aa) |
| | Piso0_002692 | Piso0_002692 protein. (1347 aa) |
| | Piso0_002653 | Lysine--tRNA ligase. (589 aa) |
| | Piso0_002624 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (503 aa) |
| | Piso0_002532 | Tyrosine--tRNA ligase. (399 aa) |
| | Piso0_002346 | Piso0_002346 protein. (655 aa) |
| | Piso0_002263 | Piso0_002263 protein; Belongs to the ubiquitin-activating E1 family. (1021 aa) |
| | Piso0_002228 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (960 aa) |
| | Piso0_002163 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (519 aa) |
| | Piso0_002141 | tRNA ligase. (835 aa) |
| | Piso0_002109 | Piso0_002109 protein. (676 aa) |
| | Piso0_002035 | Piso0_002035 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (519 aa) |
| | Piso0_001910 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (716 aa) |
| | Piso0_004280 | Piso0_004280 protein. (653 aa) |
| | Piso0_004126 | Piso0_004126 protein. (528 aa) |
| | Piso0_003978 | Piso0_003978 protein. (234 aa) |
| | Piso0_003891 | Piso0_003891 protein. (757 aa) |
| | Piso0_004507 | Piso0_004507 protein. (1156 aa) |
| | Piso0_004361 | Piso0_004361 protein. (206 aa) |
| | Piso0_004354 | Acetyl-coenzyme A synthetase. (671 aa) |
| | Piso0_004219 | Piso0_004219 protein. (312 aa) |
| | Piso0_004005 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (566 aa) |
| | Piso0_003964 | Piso0_003964 protein. (591 aa) |
| | Piso0_003957 | Piso0_003957 protein. (1093 aa) |
| | Piso0_003782 | Acetyl-coenzyme A synthetase. (679 aa) |
| | Piso0_003754 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (544 aa) |
| | Piso0_004624 | Glutathione synthetase. (494 aa) |
| | Piso0_005355-2 | Glutamine synthetase. (368 aa) |
| | Piso0_005255-2 | Piso0_005255 protein. (2304 aa) |
| | Piso0_005188-2 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1170 aa) |
| | Piso0_005081-2 | Piso0_005081 protein. (759 aa) |
| | Piso0_005064-2 | Piso0_005064 protein. (795 aa) |
| | Piso0_004989-2 | Piso0_004989 protein. (464 aa) |
| | Piso0_004970-2 | Piso0_004970 protein. (101 aa) |
| | Piso0_004903-2 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (449 aa) |
| | Piso0_004862-2 | Piso0_004862 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (793 aa) |
| | Piso0_004853-2 | Piso0_004853 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (723 aa) |
| | Piso0_004834-2 | Piso0_004834 protein. (460 aa) |
| | Piso0_004767-2 | Piso0_004767 protein. (616 aa) |
| | Piso0_005870-2 | Piso0_005870 protein. (636 aa) |
| | Piso0_005849-2 | Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion; Belongs to the GatF family. (180 aa) |
| | Piso0_005835-2 | Piso0_005835 protein. (416 aa) |
| | Piso0_005767-2 | Piso0_005767 protein. (160 aa) |
| | Piso0_005757-2 | Piso0_005757 protein. (678 aa) |
| | Piso0_005635-2 | Piso0_005635 protein. (778 aa) |
| | Piso0_005355 | Glutamine synthetase. (368 aa) |
| | Piso0_005255 | Piso0_005255 protein. (2304 aa) |
| | Piso0_005188 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1170 aa) |
| | Piso0_005081 | Piso0_005081 protein. (759 aa) |
| | Piso0_005064 | Piso0_005064 protein. (795 aa) |
| | Piso0_004989 | Piso0_004989 protein. (464 aa) |
| | Piso0_004970 | Piso0_004970 protein. (101 aa) |
| | Piso0_004903 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (449 aa) |
| | Piso0_004862 | Piso0_004862 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (793 aa) |
| | Piso0_004853 | Piso0_004853 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (723 aa) |
| | Piso0_004834 | Piso0_004834 protein. (460 aa) |
| | Piso0_004767 | Piso0_004767 protein. (616 aa) |
| | Piso0_005870 | Piso0_005870 protein. (636 aa) |
| | Piso0_005849 | Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion; Belongs to the GatF family. (179 aa) |
| | Piso0_005835 | Piso0_005835 protein. (416 aa) |
| | Piso0_005767 | Piso0_005767 protein. (160 aa) |
| | Piso0_005757 | Piso0_005757 protein. (678 aa) |
| | Piso0_005635 | Piso0_005635 protein. (777 aa) |
| | Piso0_001732-2 | Tyrosine--tRNA ligase. (515 aa) |
| | Piso0_001838-2 | Piso0_001838 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1086 aa) |
| | Piso0_000754 | Piso0_000754 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (942 aa) |
| | Piso0_000773 | Piso0_000773 protein. (546 aa) |
| | Piso0_000810 | Piso0_000810 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1081 aa) |
| | Piso0_000811 | Piso0_000811 protein. (490 aa) |
| | Piso0_000848 | Piso0_000848 protein. (437 aa) |
| | Piso0_000901 | Piso0_000901 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (375 aa) |
| | Piso0_000927 | Piso0_000927 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (627 aa) |
| | Piso0_000992 | Piso0_000992 protein. (697 aa) |
| | Piso0_001035 | Piso0_001035 protein. (470 aa) |
| | Piso0_001068 | DNA ligase. (940 aa) |
| | Piso0_000617-2 | Piso0_000617 protein. (308 aa) |
| | Piso0_000754-2 | Piso0_000754 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (942 aa) |
| | Piso0_000773-2 | Piso0_000773 protein. (546 aa) |
| | Piso0_000810-2 | Piso0_000810 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1081 aa) |
| | Piso0_000811-2 | Piso0_000811 protein. (490 aa) |
| | Piso0_000848-2 | Piso0_000848 protein. (437 aa) |
| | Piso0_000901-2 | Piso0_000901 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (375 aa) |
| | Piso0_000281-2 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (209 aa) |
| | Piso0_000240-2 | Piso0_000240 protein. (1821 aa) |
| | Piso0_000206-2 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (519 aa) |
| | Piso0_000188-2 | Piso0_000188 protein. (465 aa) |
| | Piso0_000090-2 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (482 aa) |
| | Piso0_000089-2 | Piso0_000089 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (754 aa) |
| | Piso0_000084-2 | Piso0_000084 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (580 aa) |
| | Piso0_000068-2 | Piso0_000068 protein. (328 aa) |
| | Piso0_000337 | Piso0_000337 protein. (661 aa) |
| | Piso0_000281 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (209 aa) |
| | Piso0_000240 | Piso0_000240 protein. (1821 aa) |
| | Piso0_000206 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (519 aa) |
| | Piso0_000188 | Piso0_000188 protein. (464 aa) |
| | Piso0_000090 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (482 aa) |
| | Piso0_000089 | Piso0_000089 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (754 aa) |
| | Piso0_000084 | Piso0_000084 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (580 aa) |
| | Piso0_000068 | Piso0_000068 protein. (328 aa) |
| | Piso0_001141 | Piso0_001141 protein. (108 aa) |
| | Piso0_001027 | Piso0_001027 protein. (423 aa) |
| | Piso0_000927-2 | Piso0_000927 protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (627 aa) |
