(21 nodes) RNA Polymerase II Transcription Elongation network (Trichophyton rubrum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TERG_00628	Uncharacterized protein. (489 aa)
	TERG_00346	Uncharacterized protein. (631 aa)
	TERG_02121	RPOL4c domain-containing protein. (150 aa)
	TERG_02516	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1340 aa)
	TERG_01753	RNA_pol_L_2 domain-containing protein. (160 aa)
	TERG_02559	Plus3 domain-containing protein. (637 aa)
	TERG_02034	S1 motif domain-containing protein. (191 aa)
	TERG_02089	Transcription elongation factor S-II. (297 aa)
	TERG_03429	RPOL9 domain-containing protein. (123 aa)
	TERG_03525	RPOLD domain-containing protein. (351 aa)
	TERG_02864	Uncharacterized protein. (449 aa)
	TERG_04080	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	TERG_04193	Uncharacterized protein. (1201 aa)
	TERG_04838	CDC73_C domain-containing protein. (485 aa)
	TERG_05208	Transcription factor iws1. (261 aa)
	TERG_05483	Uncharacterized protein. (889 aa)
	TERG_05742	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1258 aa)
	TERG_06461	FACT complex subunit spt16. (843 aa)
	TERG_06288	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (563 aa)
	TERG_07396	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1559 aa)
	TERG_08569	Uncharacterized protein. (339 aa)

Your Current Organism:

Trichophyton rubrum

NCBI taxonomy Id: 559305
Other names: T. rubrum CBS 118892, Trichophyton rubrum CBS 118892

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TERG_00346	TERG_00628	F2SF78	F2SCH3	Uncharacterized protein.	Uncharacterized protein.	0.501
TERG_00346	TERG_01753	F2SF78	F2SHS7	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.822
TERG_00346	TERG_02034	F2SF78	F2SJ50	Uncharacterized protein.	S1 motif domain-containing protein.	0.778
TERG_00346	TERG_02089	F2SF78	F2SJA6	Uncharacterized protein.	Transcription elongation factor S-II.	0.774
TERG_00346	TERG_02121	F2SF78	F2SFZ5	Uncharacterized protein.	RPOL4c domain-containing protein.	0.851
TERG_00346	TERG_02516	F2SF78	F2SHL9	Uncharacterized protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.871
TERG_00346	TERG_02559	F2SF78	F2SHW6	Uncharacterized protein.	Plus3 domain-containing protein.	0.954
TERG_00346	TERG_02864	F2SF78	F2SLA1	Uncharacterized protein.	Uncharacterized protein.	0.972
TERG_00346	TERG_03429	F2SF78	F2SK76	Uncharacterized protein.	RPOL9 domain-containing protein.	0.842
TERG_00346	TERG_03525	F2SF78	F2SKJ0	Uncharacterized protein.	RPOLD domain-containing protein.	0.925
TERG_00346	TERG_04080	F2SF78	F2SPT1	Uncharacterized protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.880
TERG_00346	TERG_04193	F2SF78	F2SQ44	Uncharacterized protein.	Uncharacterized protein.	0.971
TERG_00346	TERG_04838	F2SF78	F2SQH4	Uncharacterized protein.	CDC73_C domain-containing protein.	0.968
TERG_00346	TERG_05208	F2SF78	F2SRJ3	Uncharacterized protein.	Transcription factor iws1.	0.609
TERG_00346	TERG_05483	F2SF78	F2SSM9	Uncharacterized protein.	Uncharacterized protein.	0.801
TERG_00346	TERG_05742	F2SF78	F2STE4	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.881
TERG_00346	TERG_06288	F2SF78	F2SUZ2	Uncharacterized protein.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.952
TERG_00346	TERG_06461	F2SF78	F2STZ2	Uncharacterized protein.	FACT complex subunit spt16.	0.950
TERG_00346	TERG_07396	F2SF78	F2SXT8	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.520
TERG_00346	TERG_08569	F2SF78	F2T182	Uncharacterized protein.	Uncharacterized protein.	0.801