(35 nodes) RNA Polymerase II Promoter Escape network (Trichophyton rubrum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TERG_11861	Helicase ATP-binding domain-containing protein. (372 aa)
	TERG_00276	TATA-box-binding protein. (291 aa)
	TERG_01089	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (289 aa)
	TERG_00337	TFIIB-type domain-containing protein. (352 aa)
	TERG_02205	BTP domain-containing protein. (213 aa)
	TERG_02277	TFIIA_gamma_N domain-containing protein. (85 aa)
	TERG_01701	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (342 aa)
	TERG_02482	TFIID_20kDa domain-containing protein. (654 aa)
	TERG_02520	HELICc2 domain-containing protein. (290 aa)
	TERG_01941	Uncharacterized protein. (1241 aa)
	TERG_03378	DUF3591 domain-containing protein. (1126 aa)
	TERG_03436	HTH TFE/IIEalpha-type domain-containing protein. (472 aa)
	TERG_02860	Uncharacterized protein. (258 aa)
	TERG_02879	Uncharacterized protein. (190 aa)
	TERG_03831	RNA polymerase II transcription factor B subunit 5. (137 aa)
	TERG_03840	Uncharacterized protein. (337 aa)
	TERG_03108	Uncharacterized protein. (274 aa)
	TERG_04495	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (489 aa)
	TERG_04527	Uncharacterized protein. (615 aa)
	TERG_04573	TAFII28 domain-containing protein. (408 aa)
	TERG_04575	TAF domain-containing protein. (447 aa)
	TERG_03989	CYCLIN domain-containing protein. (458 aa)
	TERG_05100	Uncharacterized protein. (353 aa)
	TERG_05117	Uncharacterized protein. (413 aa)
	TERG_05590	Uncharacterized protein. (435 aa)
	TERG_05675	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (386 aa)
	TERG_05848	Uncharacterized protein. (243 aa)
	TERG_06203	WD_REPEATS_REGION domain-containing protein. (554 aa)
	TERG_06375	DUF4211 domain-containing protein. (388 aa)
	TERG_06789	CDK-activating kinase assembly factor MAT1. (400 aa)
	TERG_07105	Uncharacterized protein. (430 aa)
	TERG_07279	Uncharacterized protein. (625 aa)
	TERG_07401	Uncharacterized protein. (274 aa)
	TERG_07472	DNA repair helicase rad15. (790 aa)
	TERG_08534	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (487 aa)

Your Current Organism:

Trichophyton rubrum

NCBI taxonomy Id: 559305
Other names: T. rubrum CBS 118892, Trichophyton rubrum CBS 118892

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TERG_00276	TERG_00337	F2SEV7	F2SF70	TATA-box-binding protein.	TFIIB-type domain-containing protein.	0.999
TERG_00276	TERG_01089	F2SEV7	F2SEZ3	TATA-box-binding protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.989
TERG_00276	TERG_01701	F2SEV7	F2SHH1	TATA-box-binding protein.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.992
TERG_00276	TERG_01941	F2SEV7	F2SIV8	TATA-box-binding protein.	Uncharacterized protein.	0.999
TERG_00276	TERG_02205	F2SEV7	F2SG81	TATA-box-binding protein.	BTP domain-containing protein.	0.947
TERG_00276	TERG_02277	F2SEV7	F2SGF5	TATA-box-binding protein.	TFIIA_gamma_N domain-containing protein.	0.994
TERG_00276	TERG_02482	F2SEV7	F2SHI3	TATA-box-binding protein.	TFIID_20kDa domain-containing protein.	0.999
TERG_00276	TERG_02520	F2SEV7	F2SHM4	TATA-box-binding protein.	HELICc2 domain-containing protein.	0.897
TERG_00276	TERG_02860	F2SEV7	F2SL97	TATA-box-binding protein.	Uncharacterized protein.	0.944
TERG_00276	TERG_02879	F2SEV7	F2SLB6	TATA-box-binding protein.	Uncharacterized protein.	0.999
TERG_00276	TERG_03108	F2SEV7	F2SMK1	TATA-box-binding protein.	Uncharacterized protein.	0.946
TERG_00276	TERG_03378	F2SEV7	F2SK25	TATA-box-binding protein.	DUF3591 domain-containing protein.	0.999
TERG_00276	TERG_03436	F2SEV7	F2SK83	TATA-box-binding protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.992
TERG_00276	TERG_03831	F2SEV7	F2SMB0	TATA-box-binding protein.	RNA polymerase II transcription factor B subunit 5.	0.866
TERG_00276	TERG_03840	F2SEV7	F2SMB9	TATA-box-binding protein.	Uncharacterized protein.	0.995
TERG_00276	TERG_03989	F2SEV7	F2SPJ1	TATA-box-binding protein.	CYCLIN domain-containing protein.	0.941
TERG_00276	TERG_04495	F2SEV7	F2SNI6	TATA-box-binding protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.975
TERG_00276	TERG_04527	F2SEV7	F2SNL9	TATA-box-binding protein.	Uncharacterized protein.	0.986
TERG_00276	TERG_04573	F2SEV7	F2SNR3	TATA-box-binding protein.	TAFII28 domain-containing protein.	0.961
TERG_00276	TERG_04575	F2SEV7	F2SNR6	TATA-box-binding protein.	TAF domain-containing protein.	0.999