STRINGSTRING
zapB zapB metJ metJ ACT05028.1 ACT05028.1 ACT05069.1 ACT05069.1 ACT05070.1 ACT05070.1 ACT05192.1 ACT05192.1 slyX slyX ACT05676.1 ACT05676.1 ACT05862.1 ACT05862.1 ACT05881.1 ACT05881.1 ACT06211.1 ACT06211.1 dedD dedD ACT06248.1 ACT06248.1 lapA lapA lapB lapB proQ proQ ACT06696.1 ACT06696.1 fadR fadR lolB lolB ACT07286.1 ACT07286.1 ACT07287.1 ACT07287.1 ACT07288.1 ACT07288.1 ACT07410.1 ACT07410.1 seqA seqA syd syd rlmM rlmM ACT07999.1 ACT07999.1 ACT08000.1 ACT08000.1 mutH mutH ACT08084.1 ACT08084.1 ACT08272.1 ACT08272.1 rraB rraB ACT08665.1 ACT08665.1 ACT08948.1 ACT08948.1 yihI yihI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
zapBProtein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (80 aa)
metJMethionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa)
ACT05028.1PFAM: protein of unknown function DUF413; KEGG: eca:ECA4231 hypothetical protein. (112 aa)
ACT05069.1HemY protein; KEGG: eca:ECA4191 putative protoheme IX biogenesis protein; TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. (398 aa)
ACT05070.1Uroporphyrinogen-III C-methyltransferase; PFAM: protein of unknown function DUF513 hemX; KEGG: eca:ECA4190 putative uroporphyrinogen III C-methyltransferase. (377 aa)
ACT05192.1KEGG: eca:ECA4055 hypothetical protein. (64 aa)
slyXPFAM: SlyX family protein; KEGG: eta:ETA_31750 host factor for lysis of phiX174 infection SlyX; Belongs to the SlyX family. (72 aa)
ACT05676.1SMART: SH3 domain protein; KEGG: eca:ECA3587 putative signal transduction protein. (207 aa)
ACT05862.1PFAM: cytochrome c assembly protein; KEGG: eca:ECA3361 hypothetical protein. (264 aa)
ACT05881.1PFAM: Methyltransferase type 11; KEGG: spe:Spro_0910 methyltransferase type 11. (239 aa)
ACT06211.1PFAM: YfcL protein; KEGG: eca:ECA3065 hypothetical protein. (92 aa)
dedDSporulation domain protein; Non-essential cell division protein that could be required for efficient cell constriction. (285 aa)
ACT06248.1PFAM: protein of unknown function DUF412; KEGG: spe:Spro_3315 hypothetical protein. (151 aa)
lapAProtein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa)
lapBTetratricopeptide domain protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)
proQProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. (243 aa)
ACT06696.1KEGG: eca:ECA2459 carboxy-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family. (673 aa)
fadRFatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. (239 aa)
lolBOuter membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (206 aa)
ACT07286.1PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein NdpA. (336 aa)
ACT07287.1PFAM: protein of unknown function DUF1414; KEGG: spe:Spro_3256 hypothetical protein; Belongs to the UPF0352 family. (76 aa)
ACT07288.1PFAM: sulfatase; KEGG: eca:ECA2749 putative sulphatase. (590 aa)
ACT07410.1PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns; Belongs to the histone-like protein H-NS family. (133 aa)
seqASeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. (179 aa)
sydSyd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (182 aa)
rlmMPutative RNA 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa)
ACT07999.1PFAM: protein of unknown function DUF423; KEGG: eca:ECA1016 hypothetical protein. (128 aa)
ACT08000.1Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1015 DNA-binding transcriptional activator GcvA. (308 aa)
mutHDNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (228 aa)
ACT08084.1PFAM: protein of unknown function DUF526; KEGG: spe:Spro_4287 hypothetical protein. (94 aa)
ACT08272.1Tetratricopeptide TPR_2 repeat protein; May be involved in cell division. (294 aa)
rraBProtein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. (142 aa)
ACT08665.1PFAM: protein of unknown function DUF416; KEGG: eca:ECA0237 putative lipoprotein. (196 aa)
ACT08948.1TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0033 GNAT family acetyltransferase. (313 aa)
yihIProtein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (177 aa)
Your Current Organism:
Dickeya chrysanthemi
NCBI taxonomy Id: 561229
Other names: D. chrysanthemi Ech1591, Dickeya chrysanthemi Ech1591, Dickeya dadantii Ech1591, Dickeya zeae Ech1591
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