(56 nodes) Adipose tissue development network (Neotoma lepida)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A6R68_12976	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (418 aa)
	A6R68_12982	Uncharacterized protein. (421 aa)
	A6R68_13393	VPS13_C domain-containing protein. (685 aa)
	A6R68_00554	Uncharacterized protein. (170 aa)
	A6R68_00005	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa)
	A6R68_01193	Uncharacterized protein. (192 aa)
	A6R68_00621	Uncharacterized protein. (605 aa)
	A6R68_01405	Uncharacterized protein. (792 aa)
	A6R68_01873	Senescence domain-containing protein. (335 aa)
	A6R68_02171	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (563 aa)
	A6R68_03172	FTO_NTD domain-containing protein. (275 aa)
	A6R68_02236	Uncharacterized protein. (145 aa)
	A6R68_03497	Arrestin_C domain-containing protein. (421 aa)
	A6R68_03298	IPT/TIG domain-containing protein. (284 aa)
	A6R68_03991	Uncharacterized protein. (165 aa)
	A6R68_04198	WD_REPEATS_REGION domain-containing protein. (255 aa)
	A6R68_05137	Uncharacterized protein. (119 aa)
	A6R68_04440	FTO_CTD domain-containing protein. (67 aa)
	A6R68_04932	Chorein_N domain-containing protein. (718 aa)
	A6R68_05136	Uncharacterized protein. (98 aa)
	A6R68_06249	Protein kinase domain-containing protein. (185 aa)
	A6R68_07038	Protein kinase domain-containing protein. (713 aa)
	A6R68_07772	Uncharacterized protein. (323 aa)
	A6R68_07763	MIT domain-containing protein. (340 aa)
	A6R68_08871	Uncharacterized protein. (1339 aa)
	A6R68_08414	Uncharacterized protein. (1111 aa)
	A6R68_22240	Uncharacterized protein. (440 aa)
	A6R68_22756	Uncharacterized protein. (1049 aa)
	A6R68_23227	Uncharacterized protein. (558 aa)
	A6R68_11636	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (376 aa)
	A6R68_11090	Uncharacterized protein. (82 aa)
	A6R68_10655	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (250 aa)
	A6R68_10973	PUM-HD domain-containing protein. (281 aa)
	A6R68_10117	Fibronectin type-III domain-containing protein. (566 aa)
	A6R68_09945	Uncharacterized protein. (128 aa)
	A6R68_09621	Uncharacterized protein. (344 aa)
	A6R68_09111	PX domain-containing protein. (80 aa)
	A6R68_09104	Uncharacterized protein. (830 aa)
	A6R68_23867	Uncharacterized protein. (251 aa)
	A6R68_24279	Uncharacterized protein. (127 aa)
	A6R68_24314	DUF3498 domain-containing protein. (82 aa)
	A6R68_20385	DUF3498 domain-containing protein. (73 aa)
	A6R68_21038	TPR_REGION domain-containing protein. (427 aa)
	A6R68_21591	BZIP domain-containing protein. (233 aa)
	A6R68_21315	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1033 aa)
	A6R68_21592	Uncharacterized protein. (216 aa)
	A6R68_18576	Aminotran_1_2 domain-containing protein. (508 aa)
	A6R68_18807	Uncharacterized protein. (112 aa)
	A6R68_19153	HMG box domain-containing protein. (463 aa)
	A6R68_18900	BHLH domain-containing protein. (134 aa)
	A6R68_19528	BZIP domain-containing protein. (294 aa)
	A6R68_16524	Sep15_SelM domain-containing protein. (80 aa)
	A6R68_16235	Uncharacterized protein. (1247 aa)
	A6R68_16226	Uncharacterized protein. (335 aa)
	A6R68_14565	BZIP domain-containing protein. (348 aa)
	A6R68_13100	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (215 aa)

Your Current Organism:

Neotoma lepida

NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A6R68_00005	A6R68_00554	A0A1A6GYM5	A0A1A6GZ65	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.582
A6R68_00005	A6R68_03991	A0A1A6GYM5	A0A1A6GMF7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.582
A6R68_00005	A6R68_05136	A0A1A6GYM5	A0A1A6GJD7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.582
A6R68_00005	A6R68_05137	A0A1A6GYM5	A0A1A6GLW1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.582
A6R68_00005	A6R68_10973	A0A1A6GYM5	A0A1A6FXJ8	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	PUM-HD domain-containing protein.	0.415
A6R68_00005	A6R68_23227	A0A1A6GYM5	A0A1A6HX15	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.415
A6R68_00554	A6R68_00005	A0A1A6GZ65	A0A1A6GYM5	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.582
A6R68_00554	A6R68_04198	A0A1A6GZ65	A0A1A6GM15	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.619
A6R68_00554	A6R68_06249	A0A1A6GZ65	A0A1A6GG38	Uncharacterized protein.	Protein kinase domain-containing protein.	0.427
A6R68_00554	A6R68_09104	A0A1A6GZ65	A0A1A6G1P4	Uncharacterized protein.	Uncharacterized protein.	0.783
A6R68_00554	A6R68_09111	A0A1A6GZ65	A0A1A6G0R6	Uncharacterized protein.	PX domain-containing protein.	0.783
A6R68_00554	A6R68_09621	A0A1A6GZ65	A0A1A6G077	Uncharacterized protein.	Uncharacterized protein.	0.847
A6R68_00554	A6R68_10655	A0A1A6GZ65	A0A1A6FXD5	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.427
A6R68_00554	A6R68_10973	A0A1A6GZ65	A0A1A6FXJ8	Uncharacterized protein.	PUM-HD domain-containing protein.	0.448
A6R68_00554	A6R68_18900	A0A1A6GZ65	A0A1A6HKA7	Uncharacterized protein.	BHLH domain-containing protein.	0.577
A6R68_00554	A6R68_20385	A0A1A6GZ65	A0A1A6HSH0	Uncharacterized protein.	DUF3498 domain-containing protein.	0.847
A6R68_00554	A6R68_21315	A0A1A6GZ65	A0A1A6HR53	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.977
A6R68_00554	A6R68_23227	A0A1A6GZ65	A0A1A6HX15	Uncharacterized protein.	Uncharacterized protein.	0.448
A6R68_00554	A6R68_24314	A0A1A6GZ65	A0A1A6HTW8	Uncharacterized protein.	DUF3498 domain-containing protein.	0.847
A6R68_00621	A6R68_21315	A0A1A6GXZ5	A0A1A6HR53	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.466