(148 nodes) Papain-like cysteine peptidase superfamily network (Neotoma lepida)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A6R68_08604	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (459 aa)
	A6R68_11987	USP domain-containing protein. (168 aa)
	A6R68_11214	ULP_PROTEASE domain-containing protein. (476 aa)
	A6R68_10348	USP domain-containing protein; Belongs to the peptidase C19 family. (360 aa)
	A6R68_10237	Inhibitor_I29 domain-containing protein. (157 aa)
	A6R68_10445	Uncharacterized protein; Belongs to the peptidase C2 family. (326 aa)
	A6R68_10160	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (777 aa)
	A6R68_09899	USP domain-containing protein. (153 aa)
	A6R68_09192	Pept_C1 domain-containing protein. (79 aa)
	A6R68_08946	Ubiquitin carboxyl-terminal hydrolase. (727 aa)
	A6R68_08482	TGc domain-containing protein. (348 aa)
	A6R68_09278	TGc domain-containing protein. (645 aa)
	A6R68_08487	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (80 aa)
	A6R68_09267	Uncharacterized protein. (527 aa)
	A6R68_13588	USP domain-containing protein. (648 aa)
	A6R68_13101	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (420 aa)
	A6R68_12782	BHD_1 domain-containing protein. (604 aa)
	A6R68_12869	USP domain-containing protein; Belongs to the peptidase C19 family. (1008 aa)
	A6R68_13419	Ubiquitinyl hydrolase 1. (780 aa)
	A6R68_13372	Uncharacterized protein; Belongs to the peptidase C2 family. (287 aa)
	A6R68_12135	USP domain-containing protein. (2367 aa)
	A6R68_12038	USP domain-containing protein; Belongs to the peptidase C19 family. (1164 aa)
	A6R68_15829	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (356 aa)
	A6R68_15996	ULP_PROTEASE domain-containing protein. (165 aa)
	A6R68_15842	Uncharacterized protein; Belongs to the peptidase C1 family. (294 aa)
	A6R68_15463	Ubiquitin carboxyl-terminal hydrolase. (132 aa)
	A6R68_15491	ULP_PROTEASE domain-containing protein. (759 aa)
	A6R68_15841	Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
	A6R68_15583	TGc domain-containing protein. (649 aa)
	A6R68_14631	USP domain-containing protein. (167 aa)
	A6R68_14245	Uncharacterized protein. (862 aa)
	A6R68_14468	ULP_PROTEASE domain-containing protein. (319 aa)
	A6R68_14148	SMB domain-containing protein; Belongs to the peptidase C1 family. (466 aa)
	A6R68_14098	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (427 aa)
	A6R68_17730	NLPC_P60 domain-containing protein. (120 aa)
	A6R68_14247	Uncharacterized protein. (233 aa)
	A6R68_17618	OTU domain-containing protein. (343 aa)
	A6R68_17583	Inhibitor_I29 domain-containing protein. (94 aa)
	A6R68_14195	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (218 aa)
	A6R68_17608	USP domain-containing protein. (586 aa)
	A6R68_17598	OTU domain-containing protein. (240 aa)
	A6R68_17581	Uncharacterized protein. (129 aa)
	A6R68_17049	Inhibitor_I29 domain-containing protein. (166 aa)
	A6R68_17304	Uncharacterized protein. (226 aa)
	A6R68_17245	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (824 aa)
	A6R68_17580	Uncharacterized protein; Belongs to the peptidase C1 family. (322 aa)
	A6R68_17855	USP domain-containing protein. (408 aa)
	A6R68_17067	USP domain-containing protein. (788 aa)
	A6R68_17052	Uncharacterized protein; Belongs to the peptidase C1 family. (320 aa)
	A6R68_17362	Uncharacterized protein. (177 aa)
	A6R68_17582	Inhibitor_I29 domain-containing protein. (125 aa)
	A6R68_17053	Uncharacterized protein; Belongs to the peptidase C1 family. (433 aa)
	A6R68_16334	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (430 aa)
	A6R68_19845	Uncharacterized protein. (196 aa)
	A6R68_19918	OTU domain-containing protein. (240 aa)
	A6R68_19266	Uncharacterized protein. (329 aa)
	A6R68_19814	Uncharacterized protein; Belongs to the peptidase C1 family. (343 aa)
	A6R68_18559	USP domain-containing protein. (264 aa)
	A6R68_18819	Uncharacterized protein. (98 aa)
	A6R68_18391	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (292 aa)
	A6R68_18290	Uncharacterized protein; Belongs to the peptidase C1 family. (165 aa)
	A6R68_18390	Uncharacterized protein; Belongs to the peptidase C1 family. (286 aa)
	A6R68_18306	USP domain-containing protein. (112 aa)
	A6R68_18558	USP domain-containing protein. (137 aa)
	A6R68_18181	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (433 aa)
	A6R68_21871	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (129 aa)
	A6R68_21770	Ubiquitin carboxyl-terminal hydrolase. (170 aa)
	A6R68_21443	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (415 aa)
	A6R68_21534	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (657 aa)
	A6R68_21244	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (550 aa)
	A6R68_21952	Uncharacterized protein. (68 aa)
	A6R68_21870	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (175 aa)
	A6R68_21445	Uncharacterized protein; Belongs to the peptidase C2 family. (704 aa)
	A6R68_21151	Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
	A6R68_20918	ULP_PROTEASE domain-containing protein. (563 aa)
	A6R68_21372	TGc domain-containing protein. (558 aa)
	A6R68_20806	USP domain-containing protein; Belongs to the peptidase C19 family. (1150 aa)
	A6R68_20653	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (435 aa)
	A6R68_20612	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (402 aa)
	A6R68_20564	Uncharacterized protein. (515 aa)
	A6R68_21058	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (889 aa)
	A6R68_20301	Ubiquitin thioesterase. (271 aa)
	A6R68_20652	OTU domain-containing protein. (567 aa)
	A6R68_20601	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (666 aa)
	A6R68_24167	ULP_PROTEASE domain-containing protein. (165 aa)
	A6R68_24132	Uncharacterized protein; Belongs to the peptidase C1 family. (206 aa)
	A6R68_20273	Uncharacterized protein; Belongs to the peptidase C2 family. (683 aa)
	A6R68_23655	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (371 aa)
	A6R68_24060	Uncharacterized protein; Belongs to the peptidase C1 family. (480 aa)
	A6R68_23347	USP domain-containing protein; Belongs to the peptidase C19 family. (280 aa)
	A6R68_23274	Uncharacterized protein. (610 aa)
	A6R68_23473	Uncharacterized protein; Belongs to the peptidase C2 family. (694 aa)
	A6R68_23217	USP domain-containing protein. (94 aa)
	A6R68_23404	USP domain-containing protein. (63 aa)
	A6R68_23348	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (859 aa)
	A6R68_23507	Uncharacterized protein; Belongs to the peptidase C1 family. (435 aa)
	A6R68_23218	USP domain-containing protein. (177 aa)
	A6R68_23064	TGc domain-containing protein. (809 aa)
	A6R68_23128	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (360 aa)
	A6R68_23402	USP domain-containing protein. (1529 aa)
	A6R68_23315	Uncharacterized protein; Belongs to the peptidase C2 family. (1145 aa)
	A6R68_23244	USP domain-containing protein; Belongs to the peptidase C19 family. (609 aa)
	A6R68_22307	OTU domain-containing protein. (296 aa)
	A6R68_08636	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (306 aa)
	A6R68_08483	TGc domain-containing protein. (705 aa)
	A6R68_08488	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (446 aa)
	A6R68_08486	TGc domain-containing protein. (648 aa)
	A6R68_08460	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (404 aa)
	A6R68_08329	Uncharacterized protein. (602 aa)
	A6R68_07600	Uncharacterized protein. (229 aa)
	A6R68_07435	USP domain-containing protein. (882 aa)
	A6R68_07443	Uncharacterized protein. (1124 aa)
	A6R68_07782	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (116 aa)
	A6R68_07396	USP domain-containing protein. (179 aa)
	A6R68_07308	USP domain-containing protein. (273 aa)
	A6R68_06848	Bleomycin hydrolase; Belongs to the peptidase C1 family. (402 aa)
	A6R68_06663	OTU domain-containing protein. (395 aa)
	A6R68_05867	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (111 aa)
	A6R68_05909	Pept_C1 domain-containing protein. (65 aa)
	A6R68_05815	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
	A6R68_05878	Inhibitor_I29 domain-containing protein. (91 aa)
	A6R68_04979	PAW domain-containing protein. (1142 aa)
	A6R68_05064	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (77 aa)
	A6R68_04147	Uncharacterized protein. (698 aa)
	A6R68_05066	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (485 aa)
	A6R68_03931	USP domain-containing protein; Belongs to the peptidase C19 family. (502 aa)
	A6R68_04163	USP domain-containing protein. (1017 aa)
	A6R68_03932	USP domain-containing protein; Belongs to the peptidase C19 family. (269 aa)
	A6R68_03889	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (641 aa)
	A6R68_03359	USP domain-containing protein. (307 aa)
	A6R68_02670	Ubiquitin carboxyl-terminal hydrolase. (236 aa)
	A6R68_03037	USP domain-containing protein; Belongs to the peptidase C19 family. (381 aa)
	A6R68_02962	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (883 aa)
	A6R68_03186	Uncharacterized protein. (686 aa)
	A6R68_02772	Uncharacterized protein; Belongs to the peptidase C1 family. (373 aa)
	A6R68_02392	TGc domain-containing protein. (680 aa)
	A6R68_01680	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (170 aa)
	A6R68_01118	USP domain-containing protein. (250 aa)
	A6R68_01754	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (501 aa)
	A6R68_01148	USP domain-containing protein. (975 aa)
	A6R68_01285	OTU domain-containing protein. (476 aa)
	A6R68_01091	ULP_PROTEASE domain-containing protein. (557 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1165 aa)
	A6R68_00060	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (437 aa)
	A6R68_00147	Uncharacterized protein; Belongs to the peptidase C19 family. (809 aa)
	A6R68_00172	Uncharacterized protein. (3131 aa)
	A6R68_00727	ULP_PROTEASE domain-containing protein. (218 aa)
	A6R68_13333	Pept_C1 domain-containing protein. (119 aa)

Your Current Organism:

Neotoma lepida

NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A6R68_00060	A6R68_00147	A0A1A6GYG4	A0A1A6GZA5	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.673
A6R68_00060	A6R68_02670	A0A1A6GYG4	A0A1A6GR43	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Ubiquitin carboxyl-terminal hydrolase.	0.450
A6R68_00060	A6R68_02962	A0A1A6GYG4	A0A1A6GS56	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.744
A6R68_00060	A6R68_03186	A0A1A6GYG4	A0A1A6GSF2	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein.	0.692
A6R68_00060	A6R68_03931	A0A1A6GYG4	A0A1A6GMK9	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.635
A6R68_00060	A6R68_03932	A0A1A6GYG4	A0A1A6GNT8	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.635
A6R68_00060	A6R68_04147	A0A1A6GYG4	A0A1A6GM13	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein.	0.635
A6R68_00060	A6R68_06663	A0A1A6GYG4	A0A1A6GEY1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	OTU domain-containing protein.	0.463
A6R68_00060	A6R68_07308	A0A1A6GYG4	A0A1A6GE72	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.623
A6R68_00060	A6R68_07396	A0A1A6GYG4	A0A1A6GDY1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.704
A6R68_00060	A6R68_07435	A0A1A6GYG4	A0A1A6GCR4	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.418
A6R68_00060	A6R68_08329	A0A1A6GYG4	A0A1A6G5D4	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein.	0.455
A6R68_00060	A6R68_09267	A0A1A6GYG4	A0A1A6G2K2	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein.	0.467
A6R68_00060	A6R68_11987	A0A1A6GYG4	A0A1A6FSF8	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.635
A6R68_00060	A6R68_12869	A0A1A6GYG4	A0A1A6H2N6	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.461
A6R68_00060	A6R68_13588	A0A1A6GYG4	A0A1A6H0R2	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.436
A6R68_00060	A6R68_14631	A0A1A6GYG4	A0A1A6H8B5	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.635
A6R68_00060	A6R68_15463	A0A1A6GYG4	A0A1A6H5X6	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Ubiquitin carboxyl-terminal hydrolase.	0.450
A6R68_00060	A6R68_17304	A0A1A6GYG4	A0A1A6HD99	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	Uncharacterized protein.	0.418
A6R68_00060	A6R68_17608	A0A1A6GYG4	A0A1A6HCD1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	USP domain-containing protein.	0.570