STRINGSTRING
A6R68_00430 A6R68_00430 A6R68_01260 A6R68_01260 A6R68_00698 A6R68_00698 A6R68_00915 A6R68_00915 A6R68_00389 A6R68_00389 A6R68_00249 A6R68_00249 A6R68_00414 A6R68_00414 A6R68_13818 A6R68_13818 A6R68_13766 A6R68_13766 A6R68_12346 A6R68_12346 A6R68_12527 A6R68_12527 A6R68_13028 A6R68_13028 A6R68_12928 A6R68_12928 A6R68_12377 A6R68_12377 A6R68_12061 A6R68_12061 A6R68_12353 A6R68_12353 A6R68_15888 A6R68_15888 A6R68_15811 A6R68_15811 A6R68_15109 A6R68_15109 A6R68_15726 A6R68_15726 A6R68_15101 A6R68_15101 A6R68_17561 A6R68_17561 A6R68_17798 A6R68_17798 A6R68_17762 A6R68_17762 A6R68_17413 A6R68_17413 A6R68_17034 A6R68_17034 A6R68_17155 A6R68_17155 A6R68_17030 A6R68_17030 A6R68_17035 A6R68_17035 A6R68_16241 A6R68_16241 A6R68_16240 A6R68_16240 A6R68_11703 A6R68_11703 A6R68_11120 A6R68_11120 A6R68_11331 A6R68_11331 A6R68_10545 A6R68_10545 A6R68_11154 A6R68_11154 A6R68_10640 A6R68_10640 FEN1 FEN1 A6R68_09992 A6R68_09992 A6R68_09751 A6R68_09751 A6R68_09055 A6R68_09055 A6R68_09056 A6R68_09056 A6R68_08159 A6R68_08159 A6R68_08157 A6R68_08157 A6R68_08531 A6R68_08531 A6R68_07802 A6R68_07802 A6R68_07209 A6R68_07209 A6R68_07417 A6R68_07417 A6R68_06365 A6R68_06365 A6R68_06368 A6R68_06368 A6R68_06348 A6R68_06348 A6R68_06367 A6R68_06367 A6R68_06372 A6R68_06372 A6R68_05032 A6R68_05032 A6R68_05683 A6R68_05683 A6R68_05099 A6R68_05099 A6R68_03941 A6R68_03941 A6R68_04835 A6R68_04835 A6R68_04172 A6R68_04172 A6R68_04182 A6R68_04182 A6R68_04272 A6R68_04272 A6R68_03938 A6R68_03938 A6R68_02101 A6R68_02101 A6R68_01960 A6R68_01960 A6R68_01992 A6R68_01992 A6R68_01347 A6R68_01347 A6R68_01639 A6R68_01639 A6R68_01982 A6R68_01982 A6R68_01088 A6R68_01088 A6R68_19255 A6R68_19255 RTEL1 RTEL1 PIF1 PIF1 A6R68_18556 A6R68_18556 A6R68_18648 A6R68_18648 A6R68_22182 A6R68_22182 A6R68_20828 A6R68_20828 A6R68_20472 A6R68_20472 A6R68_20420 A6R68_20420 A6R68_24076 A6R68_24076 A6R68_20275 A6R68_20275 A6R68_23815 A6R68_23815 A6R68_23333 A6R68_23333 A6R68_23059 A6R68_23059 A6R68_22957 A6R68_22957 A6R68_23461 A6R68_23461 A6R68_22420 A6R68_22420 A6R68_22295 A6R68_22295 A6R68_19625 A6R68_19625
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A6R68_00430Protein kinase domain-containing protein. (273 aa)
A6R68_01260ANK_REP_REGION domain-containing protein. (190 aa)
A6R68_00698TruB_N domain-containing protein. (251 aa)
A6R68_00915BTB domain-containing protein. (479 aa)
A6R68_00389Uncharacterized protein. (156 aa)
A6R68_00249PCNA_C domain-containing protein. (96 aa)
A6R68_00414Uncharacterized protein. (149 aa)
A6R68_13818DNA polymerase. (930 aa)
A6R68_13766Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (402 aa)
A6R68_12346Uncharacterized protein. (159 aa)
A6R68_12527Uncharacterized protein. (107 aa)
A6R68_13028Uncharacterized protein. (137 aa)
A6R68_12928PCNA_C domain-containing protein. (242 aa)
A6R68_12377Uncharacterized protein. (571 aa)
A6R68_12061Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (291 aa)
A6R68_12353Uncharacterized protein. (237 aa)
A6R68_15888Uncharacterized protein. (295 aa)
A6R68_15811Uncharacterized protein. (103 aa)
A6R68_15109Histone H2B; Belongs to the histone H2B family. (126 aa)
A6R68_15726Uncharacterized protein. (79 aa)
A6R68_15101Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A6R68_17561PUA domain-containing protein. (486 aa)
A6R68_17798DNA_LIGASE_A3 domain-containing protein. (270 aa)
A6R68_17762Uncharacterized protein. (288 aa)
A6R68_17413H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (126 aa)
A6R68_17034ANK_REP_REGION domain-containing protein. (341 aa)
A6R68_17155ANK_REP_REGION domain-containing protein. (308 aa)
A6R68_17030ANK_REP_REGION domain-containing protein. (232 aa)
A6R68_17035ANK_REP_REGION domain-containing protein. (96 aa)
A6R68_16241Uncharacterized protein. (283 aa)
A6R68_16240Uncharacterized protein. (629 aa)
A6R68_11703Uncharacterized protein. (470 aa)
A6R68_11120Histone H2B; Belongs to the histone H2B family. (119 aa)
A6R68_11331Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (77 aa)
A6R68_10545Uncharacterized protein. (398 aa)
A6R68_11154Serine/threonine-protein phosphatase. (288 aa)
A6R68_10640RPA_C domain-containing protein. (315 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (390 aa)
A6R68_09992RPA_C domain-containing protein. (174 aa)
A6R68_097513'-5' exonuclease domain-containing protein. (152 aa)
A6R68_09055Uncharacterized protein. (910 aa)
A6R68_09056DNA_pol_B domain-containing protein. (201 aa)
A6R68_08159Helicase C-terminal domain-containing protein. (290 aa)
A6R68_08157Helicase ATP-binding domain-containing protein. (795 aa)
A6R68_08531RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (417 aa)
A6R68_07802Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
A6R68_07209Uncharacterized protein. (64 aa)
A6R68_07417Uncharacterized protein. (150 aa)
A6R68_06365PHD-type domain-containing protein. (1132 aa)
A6R68_06368Uncharacterized protein. (217 aa)
A6R68_063483'-5' exonuclease domain-containing protein. (496 aa)
A6R68_06367Uncharacterized protein. (167 aa)
A6R68_06372Helicase ATP-binding domain-containing protein. (267 aa)
A6R68_05032Replication factor C subunit 1. (963 aa)
A6R68_05683PHD-type domain-containing protein. (1133 aa)
A6R68_05099Uncharacterized protein. (96 aa)
A6R68_03941WD_REPEATS_REGION domain-containing protein. (376 aa)
A6R68_04835Uncharacterized protein. (137 aa)
A6R68_04172Uncharacterized protein. (153 aa)
A6R68_04182HTH myb-type domain-containing protein. (498 aa)
A6R68_04272Uncharacterized protein. (1136 aa)
A6R68_03938Uncharacterized protein. (1097 aa)
A6R68_02101Histone domain-containing protein; Belongs to the histone H2B family. (152 aa)
A6R68_01960Uncharacterized protein. (128 aa)
A6R68_01992ATPase_AAA_core domain-containing protein. (116 aa)
A6R68_01347Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (363 aa)
A6R68_01639Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1327 aa)
A6R68_01982Uncharacterized protein. (322 aa)
A6R68_01088Uncharacterized protein. (161 aa)
A6R68_19255Uncharacterized protein. (395 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1127 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (673 aa)
A6R68_18556RRM domain-containing protein. (180 aa)
A6R68_18648Uncharacterized protein. (708 aa)
A6R68_22182Uncharacterized protein. (167 aa)
A6R68_20828Uncharacterized protein. (462 aa)
A6R68_20472AAA domain-containing protein. (346 aa)
A6R68_20420Uncharacterized protein. (417 aa)
A6R68_24076Telo_bind domain-containing protein. (306 aa)
A6R68_20275DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (607 aa)
A6R68_23815BTB domain-containing protein. (768 aa)
A6R68_23333AAA domain-containing protein. (961 aa)
A6R68_23059Uncharacterized protein. (434 aa)
A6R68_22957DNA_pol_B_exo1 domain-containing protein. (592 aa)
A6R68_23461Uncharacterized protein. (497 aa)
A6R68_22420Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (597 aa)
A6R68_22295Uncharacterized protein. (361 aa)
A6R68_19625ANK_REP_REGION domain-containing protein. (178 aa)
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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