STRINGSTRING
A6R68_09134 A6R68_09134 A6R68_11703 A6R68_11703 A6R68_11674 A6R68_11674 A6R68_12001 A6R68_12001 A6R68_11835 A6R68_11835 A6R68_11120 A6R68_11120 A6R68_11331 A6R68_11331 A6R68_10640 A6R68_10640 FEN1 FEN1 A6R68_09992 A6R68_09992 A6R68_09129 A6R68_09129 A6R68_01992 A6R68_01992 A6R68_02319 A6R68_02319 A6R68_02587 A6R68_02587 A6R68_01759 A6R68_01759 A6R68_01166 A6R68_01166 A6R68_00863 A6R68_00863 A6R68_00085 A6R68_00085 A6R68_00915 A6R68_00915 A6R68_00249 A6R68_00249 A6R68_12527 A6R68_12527 A6R68_12928 A6R68_12928 A6R68_15109 A6R68_15109 A6R68_14985 A6R68_14985 A6R68_15101 A6R68_15101 A6R68_15088 A6R68_15088 A6R68_14440 A6R68_14440 A6R68_17798 A6R68_17798 A6R68_17762 A6R68_17762 A6R68_17675 A6R68_17675 A6R68_17676 A6R68_17676 A6R68_17673 A6R68_17673 A6R68_16708 A6R68_16708 A6R68_16190 A6R68_16190 A6R68_19701 A6R68_19701 A6R68_19005 A6R68_19005 A6R68_18301 A6R68_18301 A6R68_22182 A6R68_22182 A6R68_18222 A6R68_18222 A6R68_21830 A6R68_21830 NTHL1 NTHL1 A6R68_20899 A6R68_20899 A6R68_20828 A6R68_20828 A6R68_20314 A6R68_20314 A6R68_20472 A6R68_20472 A6R68_24271 A6R68_24271 A6R68_24070 A6R68_24070 A6R68_23815 A6R68_23815 A6R68_23640 A6R68_23640 A6R68_23538 A6R68_23538 A6R68_23262 A6R68_23262 A6R68_23139 A6R68_23139 A6R68_23263 A6R68_23263 A6R68_22770 A6R68_22770 A6R68_22957 A6R68_22957 A6R68_23461 A6R68_23461 A6R68_23433 A6R68_23433 A6R68_22420 A6R68_22420 A6R68_22295 A6R68_22295 A6R68_07802 A6R68_07802 A6R68_07016 A6R68_07016 A6R68_06570 A6R68_06570 A6R68_06975 A6R68_06975 A6R68_05032 A6R68_05032 A6R68_05099 A6R68_05099 A6R68_04362 A6R68_04362 A6R68_04835 A6R68_04835 A6R68_02801 A6R68_02801 A6R68_02101 A6R68_02101
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A6R68_09134DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (254 aa)
A6R68_11703Uncharacterized protein. (470 aa)
A6R68_11674Uncharacterized protein. (339 aa)
A6R68_12001Uncharacterized protein. (410 aa)
A6R68_11835Uncharacterized protein. (859 aa)
A6R68_11120Histone H2B; Belongs to the histone H2B family. (119 aa)
A6R68_11331Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (77 aa)
A6R68_10640RPA_C domain-containing protein. (315 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (390 aa)
A6R68_09992RPA_C domain-containing protein. (174 aa)
A6R68_09129PARP alpha-helical domain-containing protein. (266 aa)
A6R68_01992ATPase_AAA_core domain-containing protein. (116 aa)
A6R68_02319ATPase_AAA_core domain-containing protein. (1581 aa)
A6R68_02587Uncharacterized protein. (1080 aa)
A6R68_01759Poly [ADP-ribose] polymerase. (160 aa)
A6R68_01166UDG domain-containing protein. (406 aa)
A6R68_00863VIT domain-containing protein. (1256 aa)
A6R68_00085Uncharacterized protein. (200 aa)
A6R68_00915BTB domain-containing protein. (479 aa)
A6R68_00249PCNA_C domain-containing protein. (96 aa)
A6R68_12527Uncharacterized protein. (107 aa)
A6R68_12928PCNA_C domain-containing protein. (242 aa)
A6R68_15109Histone H2B; Belongs to the histone H2B family. (126 aa)
A6R68_14985FHA_2 domain-containing protein. (473 aa)
A6R68_15101Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A6R68_15088Uncharacterized protein. (325 aa)
A6R68_14440Poly [ADP-ribose] polymerase. (548 aa)
A6R68_17798DNA_LIGASE_A3 domain-containing protein. (270 aa)
A6R68_17762Uncharacterized protein. (288 aa)
A6R68_17675VIT domain-containing protein. (171 aa)
A6R68_17676Uncharacterized protein. (132 aa)
A6R68_17673VIT domain-containing protein. (383 aa)
A6R68_16708Uncharacterized protein. (90 aa)
A6R68_16190Uncharacterized protein. (294 aa)
A6R68_19701Uncharacterized protein. (133 aa)
A6R68_19005Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
A6R68_18301VWFA domain-containing protein. (126 aa)
A6R68_22182Uncharacterized protein. (167 aa)
A6R68_18222ENDO3c domain-containing protein. (346 aa)
A6R68_21830Uncharacterized protein. (515 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (311 aa)
A6R68_20899Uncharacterized protein. (368 aa)
A6R68_20828Uncharacterized protein. (462 aa)
A6R68_20314DNA_LIGASE_A3 domain-containing protein. (42 aa)
A6R68_20472AAA domain-containing protein. (346 aa)
A6R68_24271VIT domain-containing protein. (391 aa)
A6R68_24070Uncharacterized protein. (153 aa)
A6R68_23815BTB domain-containing protein. (768 aa)
A6R68_23640DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (517 aa)
A6R68_23538Uncharacterized protein. (568 aa)
A6R68_23262Uncharacterized protein. (158 aa)
A6R68_23139FPG_CAT domain-containing protein. (304 aa)
A6R68_23263Uncharacterized protein. (182 aa)
A6R68_22770Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (526 aa)
A6R68_22957DNA_pol_B_exo1 domain-containing protein. (592 aa)
A6R68_23461Uncharacterized protein. (497 aa)
A6R68_23433DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2166 aa)
A6R68_22420Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (597 aa)
A6R68_22295Uncharacterized protein. (361 aa)
A6R68_07802Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
A6R68_07016Uncharacterized protein. (985 aa)
A6R68_06570MBD domain-containing protein. (466 aa)
A6R68_06975DNA_pol_E_B domain-containing protein. (276 aa)
A6R68_05032Replication factor C subunit 1. (963 aa)
A6R68_05099Uncharacterized protein. (96 aa)
A6R68_04362FPG_CAT domain-containing protein. (389 aa)
A6R68_04835Uncharacterized protein. (137 aa)
A6R68_02801Uncharacterized protein. (191 aa)
A6R68_02101Histone domain-containing protein; Belongs to the histone H2B family. (152 aa)
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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