STRINGSTRING
queA queA RNAN_0060 RNAN_0060 RNAN_0070 RNAN_0070 rpe rpe gpmI gpmI hemL hemL ppiB ppiB pgi pgi RNAN_0317 RNAN_0317 RNAN_0369 RNAN_0369 RNAN_0390 RNAN_0390 rluE rluE murI murI gmhA gmhA diaA diaA RNAN_0674 RNAN_0674 groL1 groL1 alr alr fkpB fkpB ppiC ppiC rluF rluF RNAN_1048 RNAN_1048 hisA hisA rfbC rfbC vipB vipB wecB wecB rfbC-2 rfbC-2 rfbG rfbG pheA pheA tyrA tyrA maiA maiA ppiD ppiD tig tig ppiB-2 ppiB-2 truA truA topA topA manB manB RNAN_1591 RNAN_1591 galE galE rluB rluB trpF trpF slyD slyD nnrD nnrD rluA rluA kdsD kdsD apaG apaG surA surA rluA-2 rluA-2 RNAN_1878 RNAN_1878 RNAN_1933 RNAN_1933 parE parE parC parC RNAN_2065 RNAN_2065 fabA fabA gyrA gyrA celB celB ppiC-2 ppiC-2 prsA-2 prsA-2 RNAN_2530 RNAN_2530 purE purE RNAN_2576 RNAN_2576 fadB fadB gyrB gyrB topB topB rotA rotA mtnC mtnC rluF-2 rluF-2 rsuA rsuA mtnA mtnA RNAN_2934 RNAN_2934 rluC rluC rluA-3 rluA-3 fkpA fkpA truD truD slyD-2 slyD-2 fklB fklB fadJ fadJ folX folX RNAN_3217 RNAN_3217 truC truC deoB deoB RNAN_3296 RNAN_3296 rluA-4 rluA-4 rluA-5 rluA-5 glmM glmM tpiA tpiA truB truB dapF dapF rluD rluD rpiA rpiA fbp-2 fbp-2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (346 aa)
RNAN_0060Hypothetical protein. (347 aa)
RNAN_0070Hypothetical protein. (384 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (426 aa)
ppiBPeptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (193 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (542 aa)
RNAN_0317Hypothetical protein. (118 aa)
RNAN_03693-hydroxyisobutyryl-CoA hydrolase, mitochondrial. (380 aa)
RNAN_0390Influenza virus NS1A-binding protein. (333 aa)
rluE23S rRNA pseudouridine2457 synthase; Belongs to the pseudouridine synthase RsuA family. (218 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (271 aa)
gmhAPhosphoheptose isomerase. (193 aa)
diaADnaA initiator-associating protein. (193 aa)
RNAN_0674L-Ala-D/L-Glu epimerase. (364 aa)
groL160 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (362 aa)
fkpBFKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase. (144 aa)
ppiCPeptidyl-prolyl cis-trans isomerase C. (255 aa)
rluFRibosomal large subunit pseudouridine synthase F; Belongs to the pseudouridine synthase RsuA family. (244 aa)
RNAN_1048Hypothetical protein. (166 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (177 aa)
vipBVi polysaccharide biosynthesis protein vipB/tviC. (334 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (374 aa)
rfbC-2dTDP-4-dehydrorhamnose 3,5-epimerase. (152 aa)
rfbGCDP-glucose 4,6-dehydratase. (363 aa)
pheAChorismate mutase. (384 aa)
tyrAChorismate mutase. (376 aa)
maiAMaleylacetoacetate isomerase. (212 aa)
ppiDPeptidyl-prolyl cis-trans isomerase D. (636 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (436 aa)
ppiB-2Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
truAtRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (262 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (861 aa)
manBPhosphomannomutase. (479 aa)
RNAN_1591Kelch motif domain-containing protein. (355 aa)
galEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
rluB23S rRNA pseudouridine2605 synthase; Belongs to the pseudouridine synthase RsuA family. (336 aa)
trpFIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (463 aa)
slyDFKBP-type peptidyl-prolyl cis-trans isomerase SlyD. (162 aa)
nnrDHypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (281 aa)
rluAtRNA pseudouridine32 synthase. (300 aa)
kdsDArabinose 5-phosphate isomerase. (322 aa)
apaGApaG protein. (125 aa)
surAPeptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (429 aa)
rluA-2tRNA pseudouridine32 synthase. (218 aa)
RNAN_187823S RNA-specific pseudouridylate synthases-like protein. (280 aa)
RNAN_1933Fatty acid cistrans isomerase. (789 aa)
parETopoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa)
parCTopoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (762 aa)
RNAN_2065Glucose-6-phosphate 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (279 aa)
fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (170 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (872 aa)
celBPhosphoglucomutase. (549 aa)
ppiC-2Peptidyl-prolyl cis-trans isomerase C. (91 aa)
prsA-2Foldase protein PrsA. (275 aa)
RNAN_2530PpiC-type peptidyl-prolyl cis-trans isomerase. (284 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
RNAN_2576Zn-finger domain associated with topoisomerase type I. (180 aa)
fadB3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (717 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (805 aa)
topBDNA topoisomerase III. (675 aa)
rotAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (253 aa)
mtnCEnolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (227 aa)
rluF-223S rRNA pseudouridine2604 synthase; Belongs to the pseudouridine synthase RsuA family. (252 aa)
rsuA16S rRNA pseudouridine516 synthase; Belongs to the pseudouridine synthase RsuA family. (231 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (341 aa)
RNAN_2934Hypothetical protein. (395 aa)
rluC23S rRNA pseudouridine955/2504/2580 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (317 aa)
rluA-3tRNA pseudouridine32 synthase. (234 aa)
fkpAFKBP-type peptidyl-prolyl cis-trans isomerase FkpA. (246 aa)
truDtRNA pseudouridine13 synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (345 aa)
slyD-2FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. (161 aa)
fklBFKBP-type peptidyl-prolyl cis-trans isomerase FklB. (204 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (710 aa)
folXD-erythro-7,8-dihydroneopterin triphosphate epimerase. (121 aa)
RNAN_3217Hypothetical protein. (146 aa)
truCtRNA pseudouridine65 synthase. (270 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (404 aa)
RNAN_3296Hypothetical protein. (217 aa)
rluA-4Ribosomal large subunit pseudouridine synthase A. (224 aa)
rluA-5tRNA pseudouridine32 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (229 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
truBtRNA pseudouridine55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (307 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
rluD23S rRNA pseudouridine1911/1915/1917 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (324 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa)
fbp-2FK506-binding protein. (113 aa)
Your Current Organism:
Rheinheimera nanhaiensis
NCBI taxonomy Id: 562729
Other names: R. nanhaiensis E407-8, Rheinheimera nanhaiensis E407-8, Rheinheimera nanhaiensis str. E407-8, Rheinheimera nanhaiensis strain E407-8, Rheinheimera sp. E407-8
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