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RNAN_3349 RNAN_3349 RNAN_0032 RNAN_0032 pdhR pdhR aceE aceE aceF aceF lpdA lpdA RNAN_0068 RNAN_0068 RNAN_0075 RNAN_0075 acnB acnB RNAN_0087 RNAN_0087 glpE glpE metL metL metF metF rpe rpe argD argD yhfA yhfA gpmI gpmI RNAN_0188 RNAN_0188 glnA glnA rraA2 rraA2 maeB maeB fbp fbp ubiX ubiX RNAN_0233 RNAN_0233 gluQ gluQ RNAN_0248 RNAN_0248 hemL hemL fabV fabV nqrF nqrF apbE apbE RNAN_0279 RNAN_0279 thrA thrA thrB thrB thrC thrC pgi pgi tal tal ykfA ykfA fldB fldB RNAN_0317 RNAN_0317 RNAN_0336 RNAN_0336 RNAN_0337 RNAN_0337 gltX gltX ddh ddh lpsJ lpsJ scoA scoA RNAN_0360 RNAN_0360 thlA thlA mmsA mmsA RNAN_0369 RNAN_0369 RNAN_0425 RNAN_0425 nemA nemA RNAN_0429 RNAN_0429 RNAN_0435 RNAN_0435 RNAN_0467 RNAN_0467 pgk pgk fba fba icd icd bfd bfd rnfC rnfC RNAN_0568 RNAN_0568 thlA-2 thlA-2 frmA frmA yeiG yeiG argD-2 argD-2 gnl gnl RNAN_0674 RNAN_0674 RNAN_0675 RNAN_0675 prkB prkB nifP nifP fdx fdx yfgL yfgL accC accC accB accB queG queG ghrA ghrA RNAN_0814 RNAN_0814 lysA lysA RNAN_0876 RNAN_0876 RNAN_0909 RNAN_0909 narG narG narH narH narI narI norB norB RNAN_0935 RNAN_0935 RNAN_0936 RNAN_0936 RNAN_0945 RNAN_0945 RNAN_0956 RNAN_0956 RNAN_0979 RNAN_0979 RNAN_0994 RNAN_0994 tas tas RNAN_1081 RNAN_1081 doeB doeB gapA gapA RNAN_1230 RNAN_1230 RNAN_1240 RNAN_1240 RNAN_1251 RNAN_1251 prsA prsA exeA exeA cysC cysC RNAN_1402 RNAN_1402 acoB acoB maiA maiA RNAN_1501 RNAN_1501 hmgA hmgA folD folD RNAN_1548 RNAN_1548 RNAN_1557 RNAN_1557 accD accD asd asd manB manB yaeB yaeB scpB scpB hemA hemA prs prs RNAN_1720 RNAN_1720 RNAN_1780 RNAN_1780 RNAN_1792 RNAN_1792 RNAN_1807 RNAN_1807 fumC1 fumC1 mgsA mgsA RNAN_1851 RNAN_1851 mdh mdh hprA hprA RNAN_1910 RNAN_1910 RNAN_1929 RNAN_1929 gabD gabD RNAN_1968 RNAN_1968 RNAN_2065 RNAN_2065 gapA-2 gapA-2 yqjI yqjI gap gap fadH fadH RNAN_2101 RNAN_2101 ppsA ppsA pfkA pfkA pykA pykA hexR hexR zwf zwf pgl pgl edd edd glk glk eda eda sfcA sfcA chrB1 chrB1 RNAN_2180 RNAN_2180 serC serC RNAN_2213 RNAN_2213 gdhB gdhB bkdB-2 bkdB-2 bkdA bkdA RNAN_2248 RNAN_2248 RNAN_2250 RNAN_2250 celB celB ybgC ybgC blh blh accA accA udk udk gltB gltB gltD gltD rraA rraA RNAN_2427 RNAN_2427 RNAN_2440 RNAN_2440 RNAN_2445 RNAN_2445 RNAN_2446 RNAN_2446 acnA acnA oadB oadB oadA1 oadA1 apbE-2 apbE-2 nfuA nfuA pepQ pepQ fadB fadB fadA fadA mioC mioC cadC cadC RNAN_2648 RNAN_2648 calB calB RNAN_2672 RNAN_2672 RNAN_2686 RNAN_2686 RNAN_2699 RNAN_2699 rdoA rdoA hemB hemB fldA fldA RNAN_2828 RNAN_2828 cysJ cysJ cysI cysI cysH cysH cysG cysG cysD cysD cysN cysN cysC-2 cysC-2 cysQ cysQ ltaA ltaA ppc ppc acnA-2 acnA-2 acsA acsA sucD sucD sucC sucC sucB sucB sucA sucA sdhB sdhB sdhA sdhA sdhD sdhD sdhC sdhC gltA gltA pckA pckA cysQ-2 cysQ-2 eno eno RNAN_3130 RNAN_3130 fadJ fadJ fadI fadI RNAN_3158 RNAN_3158 damX damX RNAN_3183 RNAN_3183 paaK paaK dapE dapE RNAN_3211 RNAN_3211 RNAN_3217 RNAN_3217 dapA dapA lysC lysC dapD dapD mioC-2 mioC-2 RNAN_3280 RNAN_3280 aceA aceA aceB aceB fadR fadR nemA-2 nemA-2 vapC vapC RNAN_3367 RNAN_3367 dapB dapB tpiA tpiA RNAN_3428 RNAN_3428 RNAN_3457 RNAN_3457 RNAN_3468 RNAN_3468 hemD hemD hemC hemC lysA-2 lysA-2 dapF dapF RNAN_3480 RNAN_3480 RNAN_3496 RNAN_3496 pdxH pdxH serB serB RNAN_3506 RNAN_3506 glyA glyA RNAN_3567 RNAN_3567 RNAN_3575 RNAN_3575 RNAN_3586 RNAN_3586 alcA alcA rpiA rpiA serA serA RNAN_3749 RNAN_3749
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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RNAN_3349Hypothetical protein. (230 aa)
RNAN_0032Transcriptional regulator. (1084 aa)
pdhRGntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex. (252 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
aceFDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (540 aa)
lpdADihydrolipoyl dehydrogenase. (470 aa)
RNAN_0068Hypothetical protein. (247 aa)
RNAN_0075Malate synthase. (171 aa)
acnBAconitate hydratase 2 / 2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (865 aa)
RNAN_0087RpiR family transcriptional regulator. (289 aa)
glpEThiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (108 aa)
metLBifunctional aspartokinase / homoserine dehydrogenase 2. (790 aa)
metFMethylenetetrahydrofolate reductase; NADPH; Belongs to the methylenetetrahydrofolate reductase family. (299 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
argDacetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
yhfAProtein yhfA. (145 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
RNAN_0188Rhodanese domain-containing protein. (144 aa)
glnAGlutamine synthetase. (469 aa)
rraA2Regulator of ribonuclease activity A protein 2; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. (161 aa)
maeBMalate dehydrogenase; Oxaloacetate-decarboxylating, NADP+. (413 aa)
fbpFructose-1,6-bisphosphatase I; Belongs to the FBPase class 1 family. (323 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (212 aa)
RNAN_0233Glutamate decarboxylase. (549 aa)
gluQglutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (296 aa)
RNAN_0248Hypothetical protein. (716 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (426 aa)
fabVShort-chain alcohol dehydrogenase family enzyme; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
nqrFNa+-transporting NADH:ubiquinone oxidoreductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (410 aa)
apbEThiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (341 aa)
RNAN_0279Xanthine/uracil/vitamin C permease. (429 aa)
thrABifunctional aspartokinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (819 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (322 aa)
thrCThreonine synthase. (427 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (542 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)
ykfAProbable murein peptide carboxypeptidase. (349 aa)
fldBFlavodoxin II; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (172 aa)
RNAN_0317Hypothetical protein. (118 aa)
RNAN_0336Hypothetical protein. (347 aa)
RNAN_0337Fumarylacetoacetate (FAA) hydrolase. (221 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (469 aa)
ddh2-hydroxyacid dehydrogenase homolog; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
lpsJsuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit B. (219 aa)
scoA3-oxoacid CoA-transferase subunit A. (233 aa)
RNAN_03603-methylcrotonyl-CoA carboxylase alpha subunit. (661 aa)
thlAacetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
mmsAMethylmalonate-semialdehyde dehydrogenase. (498 aa)
RNAN_03693-hydroxyisobutyryl-CoA hydrolase, mitochondrial. (380 aa)
RNAN_0425ThiJ/PfpI domain-containing protein. (229 aa)
nemAN-ethylmaleimide reductase. (374 aa)
RNAN_0429Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
RNAN_0435Alpha/beta fold family hydrolase. (316 aa)
RNAN_0467Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa)
fbaFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
icdIsocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa)
bfdBacterioferritin-associated ferredoxin. (68 aa)
rnfCElectron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (713 aa)
RNAN_0568Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (509 aa)
thlA-2acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
frmAS-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (406 aa)
yeiGS-formylglutathione hydrolase yeiG; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
argD-2acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (438 aa)
gnlGluconolactonase. (337 aa)
RNAN_0674L-Ala-D/L-Glu epimerase. (364 aa)
RNAN_0675RpiR family transcriptional regulator. (280 aa)
prkBPhosphoribulokinase. (298 aa)
nifPProbable serine acetyltransferase. (269 aa)
fdxFerredoxin, 2Fe-2S. (112 aa)
yfgLLipoprotein yfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (393 aa)
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
queGHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (375 aa)
ghrAGlyoxylate/hydroxypyruvate reductase A. (306 aa)
RNAN_0814GCN5-related N-acetyltransferase. (197 aa)
lysADiaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (412 aa)
RNAN_0876FAD-binding protein. (527 aa)
RNAN_0909Collagenase family protease. (442 aa)
narGNitrate reductase 1, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1238 aa)
narHNitrate reductase 1, beta subunit. (511 aa)
narINitrate reductase 1, gamma subunit. (229 aa)
norBNitric oxide reductase subunit B. (755 aa)
RNAN_0935Collagenase. (330 aa)
RNAN_0936Collagenase. (290 aa)
RNAN_0945Hypothetical protein. (160 aa)
RNAN_0956Metal-dependent hydrolase. (618 aa)
RNAN_0979Zinc-binding dehydrogenase. (317 aa)
RNAN_09944,5-DOPA dioxygenase extradiol. (267 aa)
tasProtein tas. (350 aa)
RNAN_1081FMN reductase, NADPH-dependent. (182 aa)
doeBN-alpha-acetyl-L-2,4-diaminobutyrate deacetylase. (351 aa)
gapAGlyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
RNAN_1230Probable NADPH:quinone oxidoreductase 1. (181 aa)
RNAN_1240Hypothetical protein. (132 aa)
RNAN_1251Hypothetical protein. (145 aa)
prsARibose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (295 aa)
exeAGeneral secretion pathway protein A. (301 aa)
cysCProbable adenylyl-sulfate kinase; Belongs to the APS kinase family. (188 aa)
RNAN_1402Hypothetical protein. (774 aa)
acoBAcetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (330 aa)
maiAMaleylacetoacetate isomerase. (212 aa)
RNAN_1501Hypothetical protein. (338 aa)
hmgAHomogentisate 1,2-dioxygenase. (377 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
RNAN_1548Conserved hypothetical protein. (252 aa)
RNAN_1557Gluconokinase. (170 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (238 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
manBPhosphomannomutase. (479 aa)
yaeBUPF0066 protein yaeB. (236 aa)
scpBSegregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (194 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (419 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
RNAN_1720Hypothetical protein. (357 aa)
RNAN_1780Hypothetical protein. (121 aa)
RNAN_1792Ketosteroid isomerase-like protein. (145 aa)
RNAN_1807Metal-dependent amidohydrolase with the TIM-barrel fold. (549 aa)
fumC1Fumarate hydratase class II 1; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (459 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (148 aa)
RNAN_1851Hypothetical protein. (308 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
hprAGlycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
RNAN_1910Glutathione-dependent formaldehyde-activating GFA. (139 aa)
RNAN_1929Deacylase/carboxypeptidase superfamily protein. (307 aa)
gabDSuccinate-semialdehyde dehydrogenase; NADP+; Belongs to the aldehyde dehydrogenase family. (483 aa)
RNAN_1968Hypothetical protein. (309 aa)
RNAN_2065Glucose-6-phosphate 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (279 aa)
gapA-2Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
yqjI6-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (509 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (483 aa)
fadH2,4-dienoyl-CoA reductase; NADPH2. (672 aa)
RNAN_2101Aminotransferase. (376 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (329 aa)
pykAPyruvate kinase II; Belongs to the pyruvate kinase family. (478 aa)
hexRHTH-type transcriptional regulator hexR. (285 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (230 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (610 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (324 aa)
eda2-dehydro-3-deoxyphosphogluconate aldolase. (215 aa)
sfcANAD-dependent malic enzyme. (560 aa)
chrB1Protein ChrB. (290 aa)
RNAN_2180ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (341 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (378 aa)
RNAN_2213FAD linked oxidase-like protein. (1012 aa)
gdhBNAD-specific glutamate dehydrogenase. (1612 aa)
bkdB-22-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (325 aa)
bkdA2-oxoisovalerate dehydrogenase E1 component, alpha subunit. (394 aa)
RNAN_2248Hypothetical protein. (261 aa)
RNAN_2250Hypothetical protein. (120 aa)
celBPhosphoglucomutase. (549 aa)
ybgCacyl-CoA thioester hydrolase. (144 aa)
blhBeta-lactamase hydrolase-like protein. (282 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
udkUridine kinase. (210 aa)
gltBGlutamate synthase (NADPH/NADH) large chain. (1486 aa)
gltDGlutamate synthase (NADPH/NADH) small chain. (470 aa)
rraARegulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (161 aa)
RNAN_2427Twin-arginine translocation pathway signal. (296 aa)
RNAN_2440Hypothetical protein. (190 aa)
RNAN_2445Hypothetical protein. (182 aa)
RNAN_2446Hypothetical protein. (141 aa)
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
oadBOxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa)
oadA1Oxaloacetate decarboxylase alpha chain. (596 aa)
apbE-2Thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (307 aa)
nfuAFe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (192 aa)
pepQXaa-Pro dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. (441 aa)
fadB3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (717 aa)
fadAacetyl-CoA acyltransferase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)
mioCMioC protein. (145 aa)
cadCTranscriptional activator of cad operon. (692 aa)
RNAN_2648Hypothetical protein. (708 aa)
calBProbable coniferyl aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
RNAN_2672Hypothetical protein. (650 aa)
RNAN_2686PepSY-associated TM helix domain-containing protein. (383 aa)
RNAN_2699N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D. (203 aa)
rdoAProtein rdoA; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (331 aa)
hemBPorphobilinogen synthase; Belongs to the ALAD family. (335 aa)
fldAFlavodoxin-1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa)
RNAN_2828Quinone oxidoreductase PIG3. (331 aa)
cysJSulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (604 aa)
cysISulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (572 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (253 aa)
cysGuroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (473 aa)
cysDSulfate adenylyltransferase subunit 2. (303 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (478 aa)
cysC-2Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (199 aa)
cysQ3'(2'), 5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (253 aa)
ltaAL-allo-threonine aldolase. (360 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa)
acnA-2Aconitate hydratase 1. (861 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucB2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (400 aa)
sucA2-oxoglutarate dehydrogenase E1 component. (936 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
sdhDSuccinate dehydrogenase membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhCSuccinate dehydrogenase cytochrome b556 subunit. (93 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (427 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (533 aa)
cysQ-23'(2'), 5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (276 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (430 aa)
RNAN_3130UPF0350 protein. (83 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (710 aa)
fadI3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
RNAN_3158Hypothetical protein. (330 aa)
damXDamX protein. (320 aa)
RNAN_3183Polysaccharide deacetylase. (282 aa)
paaKphenylacetate-CoA ligase. (452 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)
RNAN_3211Hypothetical protein. (69 aa)
RNAN_3217Hypothetical protein. (146 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (282 aa)
lysCAspartate kinase; Belongs to the aspartokinase family. (450 aa)
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (274 aa)
mioC-2MioC protein. (149 aa)
RNAN_3280Isocitrate dehydrogenase; NAD+. (335 aa)
aceAIsocitrate lyase. (531 aa)
aceBMalate synthase A. (534 aa)
fadRFatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism. (260 aa)
nemA-2N-ethylmaleimide reductase. (351 aa)
vapCPIN (PilT N terminus) domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa)
RNAN_3367D-lactate dehydrogenase, putative. (923 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
RNAN_3428DoxX family protein. (200 aa)
RNAN_3457Class II aldolase/adducin family protein. (213 aa)
RNAN_3468Hypothetical protein. (371 aa)
hemDuroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (253 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
RNAN_3480DoxD-like family protein. (148 aa)
RNAN_3496Polyketide synthase 1/15. (335 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (212 aa)
serBPhosphoserine phosphatase. (358 aa)
RNAN_3506Esterase/lipase. (298 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
RNAN_3567Hypothetical protein. (252 aa)
RNAN_3575Hypothetical protein. (162 aa)
RNAN_3586Hypothetical protein. (110 aa)
alcAAlcaligin biosynthesis enzyme. (446 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa)
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (408 aa)
RNAN_3749ThiJ/PfpI. (254 aa)
Your Current Organism:
Rheinheimera nanhaiensis
NCBI taxonomy Id: 562729
Other names: R. nanhaiensis E407-8, Rheinheimera nanhaiensis E407-8, Rheinheimera nanhaiensis str. E407-8, Rheinheimera nanhaiensis strain E407-8, Rheinheimera sp. E407-8
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