STRINGSTRING
pilN pilN clpB clpB secG secG RNAN_3194 RNAN_3194 ftsB ftsB exeC exeC epsD-2 epsD-2 epsE-2 epsE-2 exeF exeF outG outG xcpU xcpU gspI gspI epsJ epsJ exeK exeK exeL exeL exeM exeM RNAN_2895 RNAN_2895 tatA tatA tatB tatB tatC tatC RNAN_2646 RNAN_2646 traN traN oxaA oxaA slt slt RNAN_2489 RNAN_2489 RNAN_2034 RNAN_2034 RNAN_2033 RNAN_2033 clpV1 clpV1 RNAN_2023 RNAN_2023 RNAN_2021 RNAN_2021 RNAN_2020 RNAN_2020 RNAN_2018 RNAN_2018 RNAN_2017 RNAN_2017 RNAN_2016 RNAN_2016 tolC tolC lptC lptC hlyD hlyD RNAN_1422 RNAN_1422 RNAN_1417 RNAN_1417 RNAN_1301 RNAN_1301 RNAN_1300 RNAN_1300 RNAN_1299 RNAN_1299 RNAN_1297 RNAN_1297 epsE epsE pilC pilC RNAN_1292 RNAN_1292 RNAN_1291 RNAN_1291 RNAN_1290 RNAN_1290 RNAN_1289 RNAN_1289 RNAN_1288 RNAN_1288 RNAN_1069 RNAN_1069 secD-2 secD-2 secF-2 secF-2 RNAN_0938 RNAN_0938 RNAN_0842 RNAN_0842 RNAN_0838 RNAN_0838 RNAN_0837 RNAN_0837 RNAN_0833 RNAN_0833 RNAN_0832 RNAN_0832 RNAN_0831 RNAN_0831 secA secA clpA clpA secB secB pilQ pilQ pilM pilM ftsY ftsY tapB tapB tapC tapC tapD tapD secF secF secD secD yajC yajC secE secE secY secY ffh ffh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pilNType IV pilus assembly protein PilN. (197 aa)
clpBATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (858 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (109 aa)
RNAN_3194SEC-C motif domain protein. (158 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (99 aa)
exeCGeneral secretion pathway protein C. (317 aa)
epsD-2General secretion pathway protein D. (706 aa)
epsE-2General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (502 aa)
exeFGeneral secretion pathway protein F. (407 aa)
outGGeneral secretion pathway protein G. (150 aa)
xcpUGeneral secretion pathway protein H. (197 aa)
gspIGeneral secretion pathway protein I. (122 aa)
epsJGeneral secretion pathway protein J. (207 aa)
exeKGeneral secretion pathway protein K. (331 aa)
exeLGeneral secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (395 aa)
exeMGeneral secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (156 aa)
RNAN_2895HlyD family secretion protein. (411 aa)
tatASec-independent protein translocase protein tatA/E homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (91 aa)
tatBSec-independent protein translocase protein tatB homolog. (111 aa)
tatCSec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (258 aa)
RNAN_2646Toxin secretion, membrane fusion protein. (416 aa)
traNConjugal transfer mating pair stabilization protein TraN. (929 aa)
oxaAInner membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (545 aa)
sltSoluble lytic murein transglycosylase. (631 aa)
RNAN_2489Rhs element Vgr protein. (595 aa)
RNAN_2034Type VI secretion system Vgr family protein. (604 aa)
RNAN_2033Hypothetical protein. (159 aa)
clpV1Protein ClpV1; Belongs to the ClpA/ClpB family. (866 aa)
RNAN_2023Protein phosphatase. (256 aa)
RNAN_2021Type VI secretion system protein ImpL. (1182 aa)
RNAN_2020Type VI secretion system protein ImpK. (436 aa)
RNAN_2018Type VI secretion system protein VasD. (160 aa)
RNAN_2017Type VI secretion system protein. (444 aa)
RNAN_2016Serine/threonine protein kinase, bacterial. (669 aa)
tolCOuter membrane channel protein TolC. (451 aa)
lptCHypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (184 aa)
hlyDHemolysin secretion protein D, chromosomal. (467 aa)
RNAN_1422Hypothetical protein. (482 aa)
RNAN_1417Hypothetical protein. (567 aa)
RNAN_1301Hypothetical protein. (303 aa)
RNAN_1300Hypothetical protein. (198 aa)
RNAN_1299Hypothetical protein. (216 aa)
RNAN_1297MSHA biogenesis protein MshL. (553 aa)
epsEGeneral secretion pathway protein E. (574 aa)
pilCType IV pilus assembly protein PilC. (409 aa)
RNAN_1292Hypothetical protein. (176 aa)
RNAN_1291Type II secretory pathway, pseudopilin. (170 aa)
RNAN_1290MSHA pilin protein MshC. (148 aa)
RNAN_1289Pilin protein. (182 aa)
RNAN_1288Tfp-like pilus assembly protein. (253 aa)
RNAN_1069Lytic transglycosylase. (229 aa)
secD-2Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (615 aa)
secF-2Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (312 aa)
RNAN_0938Protein serine/threonine phosphatase. (578 aa)
RNAN_0842Type IV pilus biogenesis protein, putative. (168 aa)
RNAN_0838Hypothetical protein. (316 aa)
RNAN_0837Hypothetical protein. (163 aa)
RNAN_0833Hypothetical protein. (328 aa)
RNAN_0832Pre-pilin leader sequence. (144 aa)
RNAN_0831Pre-pilin like leader sequence. (181 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (905 aa)
clpAATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (755 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (162 aa)
pilQType IV pilus assembly protein PilQ. (688 aa)
pilMType IV pilus assembly protein PilM. (359 aa)
ftsYFused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (396 aa)
tapBType IV pilus assembly protein tapB. (565 aa)
tapCType IV pilus assembly protein tapC. (410 aa)
tapDType 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (292 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (617 aa)
yajCPreprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (113 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (124 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (442 aa)
ffhSignal recognition particle subunit SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual co [...] (455 aa)
Your Current Organism:
Rheinheimera nanhaiensis
NCBI taxonomy Id: 562729
Other names: R. nanhaiensis E407-8, Rheinheimera nanhaiensis E407-8, Rheinheimera nanhaiensis str. E407-8, Rheinheimera nanhaiensis strain E407-8, Rheinheimera sp. E407-8
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