Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGW46653.1 | EGW46862.1 | HMPREF0666_02144 | HMPREF0666_01964 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Hypothetical protein. | 0.410 |
| EGW46653.1 | EGW47274.1 | HMPREF0666_02144 | HMPREF0666_01581 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Hypothetical protein. | 0.924 |
| EGW46653.1 | EGW47508.1 | HMPREF0666_02144 | HMPREF0666_01385 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Hypothetical protein. | 0.990 |
| EGW46653.1 | EGW47642.1 | HMPREF0666_02144 | HMPREF0666_01201 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.548 |
| EGW46653.1 | EGW48319.1 | HMPREF0666_02144 | HMPREF0666_00567 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Hypothetical protein. | 0.726 |
| EGW46653.1 | EGW48342.1 | HMPREF0666_02144 | HMPREF0666_00590 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.476 |
| EGW46653.1 | EGW48364.1 | HMPREF0666_02144 | HMPREF0666_00502 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.996 |
| EGW46653.1 | fhs | HMPREF0666_02144 | HMPREF0666_00533 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.578 |
| EGW46653.1 | fmt | HMPREF0666_02144 | HMPREF0666_01685 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.518 |
| EGW46653.1 | folD | HMPREF0666_02144 | HMPREF0666_01889 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | folD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.885 |
| EGW46653.1 | glyA | HMPREF0666_02144 | HMPREF0666_01812 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.904 |
| EGW46653.1 | luxS | HMPREF0666_02144 | HMPREF0666_00186 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.534 |
| EGW46653.1 | metAA | HMPREF0666_02144 | HMPREF0666_01572 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.879 |
| EGW46653.1 | metK | HMPREF0666_02144 | HMPREF0666_02932 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.803 |
| EGW46653.1 | thyA | HMPREF0666_02144 | HMPREF0666_00588 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.760 |
| EGW46862.1 | EGW46653.1 | HMPREF0666_01964 | HMPREF0666_02144 | Hypothetical protein. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.410 |
| EGW46862.1 | EGW47508.1 | HMPREF0666_01964 | HMPREF0666_01385 | Hypothetical protein. | Hypothetical protein. | 0.554 |
| EGW46862.1 | EGW48319.1 | HMPREF0666_01964 | HMPREF0666_00567 | Hypothetical protein. | Hypothetical protein. | 0.549 |
| EGW46862.1 | EGW48364.1 | HMPREF0666_01964 | HMPREF0666_00502 | Hypothetical protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.554 |
| EGW46862.1 | EGW48611.1 | HMPREF0666_01964 | HMPREF0666_00255 | Hypothetical protein. | Hypothetical protein; Belongs to the folylpolyglutamate synthase family. | 0.410 |
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