STRINGSTRING
EGW48857.1 EGW48857.1 EGW48870.1 EGW48870.1 dxs dxs EGW48993.1 EGW48993.1 EGW48981.1 EGW48981.1 udk udk EGW49075.1 EGW49075.1 EGW49087.1 EGW49087.1 EGW49116.1 EGW49116.1 EGW49167.1 EGW49167.1 EGW49176.1 EGW49176.1 EGW49182.1 EGW49182.1 EGW49181.1 EGW49181.1 EGW49195.1 EGW49195.1 pdxT pdxT pdxS pdxS EGW49269.1 EGW49269.1 EGW49245.1 EGW49245.1 EGW49233.1 EGW49233.1 EGW49298.1 EGW49298.1 EGW49376.1 EGW49376.1 pyrG pyrG EGW49486.1 EGW49486.1 EGW46204.1 EGW46204.1 lipA lipA guaB guaB EGW46328.1 EGW46328.1 pyrE pyrE dut dut ackA ackA dacA dacA EGW46352.1 EGW46352.1 EGW46360.1 EGW46360.1 apt apt polA polA EGW46444.1 EGW46444.1 purE purE EGW46436.1 EGW46436.1 EGW46435.1 EGW46435.1 EGW46433.1 EGW46433.1 EGW46423.1 EGW46423.1 EGW46422.1 EGW46422.1 EGW46542.1 EGW46542.1 rpoA rpoA rpoC rpoC rpoB rpoB nusG nusG EGW46553.1 EGW46553.1 priA priA EGW46740.1 EGW46740.1 EGW46722.1 EGW46722.1 EGW46721.1 EGW46721.1 folE folE xpt xpt EGW46678.1 EGW46678.1 pyrH pyrH EGW46661.1 EGW46661.1 tdk tdk EGW46652.1 EGW46652.1 EGW46644.1 EGW46644.1 ribBA ribBA EGW46618.1 EGW46618.1 adk adk EGW46611.1 EGW46611.1 EGW46788.1 EGW46788.1 EGW46787.1 EGW46787.1 queC queC EGW46902.1 EGW46902.1 nadA nadA EGW46900.1 EGW46900.1 EGW46862.1 EGW46862.1 EGW46836.1 EGW46836.1 EGW46814.1 EGW46814.1 EGW46813.1 EGW46813.1 EGW46959.1 EGW46959.1 pyrD pyrD folD folD EGW46976.1 EGW46976.1 EGW47071.1 EGW47071.1 tgt tgt EGW47006.1 EGW47006.1 carA carA EGW47145.1 EGW47145.1 EGW47138.1 EGW47138.1 EGW47136.1 EGW47136.1 EGW47106.1 EGW47106.1 EGW47102.1 EGW47102.1 EGW47099.1 EGW47099.1 EGW47097.1 EGW47097.1 guaA guaA EGW47191.1 EGW47191.1 EGW47190.1 EGW47190.1 EGW47275.1 EGW47275.1 cmk cmk EGW47356.1 EGW47356.1 EGW47341.1 EGW47341.1 EGW47405.1 EGW47405.1 EGW47404.1 EGW47404.1 dnaX dnaX EGW47509.1 EGW47509.1 queF queF EGW47492.1 EGW47492.1 coaE coaE EGW47476.1 EGW47476.1 dnaG dnaG EGW47625.1 EGW47625.1 EGW47644.1 EGW47644.1 EGW47641.1 EGW47641.1 EGW47721.1 EGW47721.1 EGW47704.1 EGW47704.1 EGW47685.1 EGW47685.1 EGW47806.1 EGW47806.1 EGW47803.1 EGW47803.1 EGW47776.1 EGW47776.1 EGW47774.1 EGW47774.1 EGW47884.1 EGW47884.1 purA purA pncB pncB thiL thiL coaD coaD EGW48085.1 EGW48085.1 EGW48076.1 EGW48076.1 EGW47997.1 EGW47997.1 nadK nadK EGW47968.1 EGW47968.1 nusA nusA EGW48128.1 EGW48128.1 EGW48127.1 EGW48127.1 nadD nadD gmk gmk murA murA purL purL EGW48265.1 EGW48265.1 EGW48256.1 EGW48256.1 EGW48342.1 EGW48342.1 thyA thyA EGW48334.1 EGW48334.1 kdsB kdsB EGW48327.1 EGW48327.1 pyrF pyrF purC purC rho rho EGW48295.1 EGW48295.1 purD purD EGW48280.1 EGW48280.1 EGW48367.1 EGW48367.1 EGW48360.1 EGW48360.1 serC serC nadE nadE EGW48429.1 EGW48429.1 EGW48425.1 EGW48425.1 EGW48424.1 EGW48424.1 pyrB pyrB pyrI pyrI EGW48400.1 EGW48400.1 purT purT EGW48384.1 EGW48384.1 fcl fcl EGW48485.1 EGW48485.1 EGW48484.1 EGW48484.1 EGW48462.1 EGW48462.1 ribH ribH EGW48535.1 EGW48535.1 EGW48611.1 EGW48611.1 dinB dinB EGW48645.1 EGW48645.1 EGW48680.1 EGW48680.1 atpD atpD EGW48225.1 EGW48225.1 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EGW48857.1Hypothetical protein. (332 aa)
EGW48870.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (158 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa)
EGW48993.1Hypothetical protein. (686 aa)
EGW48981.1Hypothetical protein. (570 aa)
udkUridine kinase. (211 aa)
EGW49075.1Hypothetical protein. (96 aa)
EGW49087.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (408 aa)
EGW49116.1Hypothetical protein. (219 aa)
EGW49167.1Hypothetical protein. (223 aa)
EGW49176.1Hypothetical protein. (287 aa)
EGW49182.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa)
EGW49181.1Hypothetical protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (866 aa)
EGW49195.1Hypothetical protein; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base; Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family. (139 aa)
pdxTHypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (195 aa)
pdxSPyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (290 aa)
EGW49269.1Hypothetical protein. (317 aa)
EGW49245.1Hypothetical protein. (272 aa)
EGW49233.1uroporphyrinogen-III synthase. (251 aa)
EGW49298.1Hypothetical protein. (419 aa)
EGW49376.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa)
EGW49486.1Hypothetical protein. (149 aa)
EGW46204.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
lipAHypothetical protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (607 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa)
EGW46328.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (380 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (145 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (258 aa)
EGW46352.1Dihydropteroate synthase. (280 aa)
EGW46360.1Hypothetical protein. (557 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
polAHypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (920 aa)
EGW46444.1RNA polymerase sigma-54 factor. (504 aa)
purEAIR carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa)
EGW46436.1Hypothetical protein. (441 aa)
EGW46435.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa)
EGW46433.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
EGW46423.1Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (349 aa)
EGW46422.1Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (839 aa)
EGW46542.1Hypothetical protein. (460 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1456 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1269 aa)
nusGTranscription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (182 aa)
EGW46553.1ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (191 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (768 aa)
EGW46740.1Hypothetical protein. (322 aa)
EGW46722.1Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (394 aa)
EGW46721.17, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (136 aa)
folEGTP cyclohydrolase 1. (197 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
EGW46678.1Hypothetical protein. (1239 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
EGW46661.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (160 aa)
tdkHypothetical protein. (589 aa)
EGW46652.1Hypothetical protein. (379 aa)
EGW46644.1Hypothetical protein. (198 aa)
ribBARiboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa)
EGW46618.1Hypothetical protein. (393 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa)
EGW46611.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
EGW46788.1Hypothetical protein. (206 aa)
EGW46787.1Hypothetical protein. (211 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (218 aa)
EGW46902.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (536 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (330 aa)
EGW46900.1Nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family. (286 aa)
EGW46862.1Hypothetical protein. (140 aa)
EGW46836.1Hypothetical protein. (300 aa)
EGW46814.1Hypothetical protein. (217 aa)
EGW46813.1Ribose-phosphate pyrophosphokinase. (312 aa)
EGW46959.1Hypothetical protein. (258 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (302 aa)
folDfolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
EGW46976.1Hypothetical protein; Belongs to the PdxA family. (378 aa)
EGW47071.1Hypothetical protein. (330 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa)
EGW47006.1Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
carACarbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (358 aa)
EGW47145.1Hypothetical protein. (633 aa)
EGW47138.1Hypothetical protein. (418 aa)
EGW47136.1Hypothetical protein. (108 aa)
EGW47106.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (295 aa)
EGW47102.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
EGW47099.1Hypothetical protein; Belongs to the TrpF family. (214 aa)
EGW47097.1Hypothetical protein. (189 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (514 aa)
EGW47191.1Hypothetical protein. (350 aa)
EGW47190.1Hypothetical protein. (296 aa)
EGW47275.1Hypothetical protein. (298 aa)
cmkCytidylate kinase. (230 aa)
EGW47356.1Hypothetical protein. (455 aa)
EGW47341.1Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (310 aa)
EGW47405.1Hypothetical protein. (297 aa)
EGW47404.1Hypothetical protein. (54 aa)
dnaXHypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (603 aa)
EGW47509.1Hypothetical protein. (449 aa)
queFNADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (151 aa)
EGW47492.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (218 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (187 aa)
EGW47476.1Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (357 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (634 aa)
EGW47625.1Hypothetical protein. (353 aa)
EGW47644.1Hypothetical protein. (2520 aa)
EGW47641.1Hypothetical protein. (318 aa)
EGW47721.1Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (586 aa)
EGW47704.1Hypothetical protein. (354 aa)
EGW47685.1Hypothetical protein. (436 aa)
EGW47806.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (180 aa)
EGW47803.1Hypothetical protein. (382 aa)
EGW47776.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
EGW47774.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
EGW47884.1Hypothetical protein. (82 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (401 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (369 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (148 aa)
EGW48085.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa)
EGW48076.1Hypothetical protein. (223 aa)
EGW47997.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (296 aa)
EGW47968.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (421 aa)
EGW48128.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (454 aa)
EGW48127.1Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa)
nadDNicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
gmkHypothetical protein; Essential for recycling GMP and indirectly, cGMP. (367 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (437 aa)
purLHypothetical protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1248 aa)
EGW48265.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa)
EGW48256.1Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (228 aa)
EGW48342.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
EGW48334.1Hypothetical protein. (506 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (246 aa)
EGW48327.1Hypothetical protein. (387 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (275 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (316 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (650 aa)
EGW48295.1Hypothetical protein. (505 aa)
purDPhosphoribosylamine-glycine ligase; Belongs to the GARS family. (422 aa)
EGW48280.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (512 aa)
EGW48367.1Hypothetical protein; Belongs to the CinA family. (167 aa)
EGW48360.1Hypothetical protein. (268 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (356 aa)
nadEHypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (656 aa)
EGW48429.1Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (423 aa)
EGW48425.1Hypothetical protein. (331 aa)
EGW48424.1Hypothetical protein. (318 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa)
pyrIAspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (153 aa)
EGW48400.1Hypothetical protein. (206 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa)
EGW48384.1Riboflavin synthase, alpha subunit. (201 aa)
fclHypothetical protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (400 aa)
EGW48485.1Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (453 aa)
EGW48484.1Hypothetical protein. (276 aa)
EGW48462.1Hypothetical protein. (308 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (158 aa)
EGW48535.1Hypothetical protein. (277 aa)
EGW48611.1Hypothetical protein; Belongs to the folylpolyglutamate synthase family. (430 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (358 aa)
EGW48645.1Hypothetical protein. (531 aa)
EGW48680.1Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
atpDATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (507 aa)
EGW48225.1ATP synthase, Delta/Epsilon chain, beta-sandwich domain-containing protein. (79 aa)
atpBHypothetical protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (365 aa)
atpEHypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa)
atpFATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (527 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (325 aa)
Your Current Organism:
Prevotella sp. C561
NCBI taxonomy Id: 563031
Other names: P. sp. C561
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