STRINGSTRING
Saut_0047 Saut_0047 Saut_0048 Saut_0048 Saut_1107 Saut_1107 sucC sucC sucD sucD Saut_1256 Saut_1256 Saut_1257 Saut_1257 Saut_1258 Saut_1258 Saut_1577 Saut_1577 Saut_1578 Saut_1578
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Saut_0047COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027:IPR004112:IPR006076:IPR003953; KEGG: tdn:Suden_0037 succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: O29576 Succinate dehydrogenase, flavoprotein subunit A (SdhA); PFAM: domain; FAD binding domain; TIGRFAM: flavocytochrome c. (507 aa)
Saut_0048COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR001041:IPR001450:IPR017900:IPR004489; KEGG: tdn:Suden_0038 succinate dehydrogenase/fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; SPTR: A3IXM6 Succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (235 aa)
Saut_1107Aconitase; COGs: COG1049 Aconitase B; InterPro IPR015929:IPR001030:IPR018136:IPR004406; KEGG: tdn:Suden_1040 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; SPTR: Q9ZL64 Aconitate hydratase 2; TIGRFAM: aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (849 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
Saut_1256COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027:IPR004112:IPR006076:IPR003953:IPR 003952:IPR014006; KEGG: tdn:Suden_1030 succinate dehydrogenase/fumarate reductase subunit A; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: A3IN99 Succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarat [...] (570 aa)
Saut_1257COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR017907:IPR006058:IPR001041:IPR017900:IPR 004489; KEGG: tdn:Suden_1029 succinate dehydrogenase/fumarate reductase subunit B; PRIAM: Succinate dehydrogenase; SPTR: A0ZA48 Succinate dehydrogenase; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (326 aa)
Saut_1258COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: tdn:Suden_1028 succinate dehydrogenase/fumarate reductase subunit C; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: A1HLP7 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (293 aa)
Saut_1577ATP-citrate lyase/succinyl-CoA ligase; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR005811:IPR017440; KEGG: sun:SUN_0542 ATP citrate synthase, subunit 2; PFAM: ATP-citrate lyase/succinyl-CoA ligase; SPTR: A1Y9H8 ATP citrate lyase alpha subunit (Fragment); PFAM: CoA-ligase; Citrate synthase. (604 aa)
Saut_1578ATP citrate lyase subunit 1; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650; KEGG: tdn:Suden_0570 ATP-dependent citrate lyase beta subunit; PFAM: ATP-grasp domain protein; SPTR: A1Y9H5 ATP citrate lyase beta subunit; PFAM: ATP-grasp domain. (446 aa)
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
Server load: low (14%) [HD]