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| | Saut_0566 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | Saut_0008 | Alcohol O-acetyltransferase; COGs: COG0429 hydrolase of the alpha/beta-hydrolase fold; InterPro IPR000073:IPR000952; KEGG: lpc:LPC_1051 alpha/beta hydrolase; PFAM: alpha/beta hydrolase fold; PRIAM: Alcohol O-acetyltransferase; SPTR: A0Y430 Putative enzyme with alpha/beta-hydrolase domain; PFAM: alpha/beta hydrolase fold. (323 aa) |
| | Saut_0049 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006067:IPR005117:IPR006066; KEGG: tdn:Suden_1241 ferredoxin--nitrite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: A0YL91 Nitrite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain. (571 aa) |
| | Saut_0058 | Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: tdn:Suden_0110 phosphoglycerate/bisphosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: P52086 Alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase family. (187 aa) |
| | Saut_0063 | InterPro IPR020003; KEGG: nis:NIS_0025 hypothetical protein; SPTR: O67918 Uncharacterized protein aq_2168. (422 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (462 aa) |
| | Saut_0088 | Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: gme:Gmet_0487 L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: O58115 328aa long hypothetical histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II. (336 aa) |
| | Saut_0089 | Aminoglycoside phosphotransferase; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: csa:Csal_0546 homoserine kinase; PFAM: aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family. (266 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (357 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (421 aa) |
| | Saut_0117 | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR001962:IPR000583:IPR006426; KEGG: tdn:Suden_0163 asparagine synthase, glutamine-hydrolyzing; PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: A3I8W6 Asparagine synthetase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (599 aa) |
| | Saut_0119 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (285 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (280 aa) |
| | Saut_0138 | LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: cla:Cla_1324 LmbE-like protein; PFAM: LmbE family protein; SPTR: A3W9N6 Putative LmbE-like protein; PFAM: GlcNAc-PI de-N-acetylase. (226 aa) |
| | Saut_0204 | Malate dehydrogenase (oxaloacetate-decarboxylating); COGs: COG0281 Malic enzyme; InterPro IPR012302:IPR012301:IPR015884; KEGG: sun:SUN_0515 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: A3LJ82 Malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (434 aa) |
| | Saut_0237 | Chorismate mutase; InterPro IPR002701; KEGG: tdn:Suden_0309 chorismate mutase; PFAM: Chorismate mutase; SPTR: Q64EM5 Putative uncharacterized protein; PFAM: Chorismate mutase type II. (97 aa) |
| | selD | Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (343 aa) |
| | panD | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (121 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (273 aa) |
| | Saut_0338 | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR004113:IPR006094; KEGG: tdn:Suden_0372 FAD linked oxidase-like; PFAM: FAD linked oxidase domain protein; SPTR: A1HPQ0 FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (461 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (352 aa) |
| | Saut_0345 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (339 aa) |
| | Saut_0354 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (306 aa) |
| | Saut_0356 | COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002306:IPR002305:IPR001412; KEGG: tdn:Suden_0389 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Q5HW79 Tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase. (321 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218:IPR006269; KEGG: tdn:Suden_0401 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: Q7VK53 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. (264 aa) |
| | glsA | L-glutaminase; COGs: COG2066 Glutaminase; InterPro IPR015868; KEGG: abu:Abu_2331 glutaminase A; PFAM: Glutaminase, core; PRIAM: Glutaminase; SPTR: A8EX66 Glutaminase; PFAM: Glutaminase; Belongs to the glutaminase family. (307 aa) |
| | argS | COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR015945:IPR005148:IPR008909:IPR001412:IPR 001278; KEGG: tdn:Suden_1794 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Q30PL3 Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. (531 aa) |
| | Saut_0459 | KEGG: sun:SUN_1032 hypothetical protein; PFAM: Protein of unknown function (DUF540). (315 aa) |
| | Saut_0461 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (804 aa) |
| | Saut_0463 | COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: sun:SUN_1211 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Fructose-bisphosphate aldolase; SPTR: Q46G31 Fructose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase. (300 aa) |
| | pgi | COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: sun:SUN_1276 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Q9PMD4 Probable glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (420 aa) |
| | Saut_0483 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: sun:SUN_0970 pyruvate/2-oxoglutarate dehydrogenase complex, E1 component, alpha subunit; PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: Q6B8T2 Pyruvate dehydrogenase E1 component alpha subunit; PFAM: Dehydrogenase E1 component. (318 aa) |
| | Saut_0484 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa) |
| | Saut_0485 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR001078:IPR003016:IPR000276; KEGG: sun:SUN_1209 pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; SPTR: A3XR08 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; PFAM: 2-oxoacid dehydrogenase [...] (422 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (277 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (232 aa) |
| | plsX | Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa) |
| | pgk | COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911; KEGG: tdn:Suden_1753 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Q30PQ4 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (234 aa) |
| | Saut_0534 | Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347; KEGG: tdn:Suden_1751 enoyl-(acyl carrier protein) reductase; SPTR: O24990 Enoyl-[acyl-carrier-protein] reductase [NADH]; PFAM: short chain dehydrogenase. (273 aa) |
| | Saut_0556 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459:IPR000873; KEGG: sun:SUN_0967 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q0W3Y0 Acetyl-CoA synthetase (AMP-forming); PFAM: AMP-binding enzyme. (583 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (322 aa) |
| | Saut_0558 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) |
| | Saut_0559 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR000089:IPR001078:IPR003016; KEGG: sun:SUN_0968 pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: A3U7G2 Dihydrolipoamide acetyltransferase component (E2) of pyruvatedehydrogenase complex; PFA [...] (385 aa) |
| | Saut_0560 | Phosphopantetheine-binding protein; InterPro IPR006163:IPR009081; KEGG: sun:SUN_0969 acyl carrier protein ACP; PFAM: phosphopantetheine-binding; SPTR: A3EU90 Acyl carrier protein; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein. (80 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (491 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (75 aa) |
| | Saut_0568 | 3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (405 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | trpF | COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: tdn:Suden_1606 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: A6QC86 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (194 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (392 aa) |
| | leuS | COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR002300:IPR001412; KEGG: tdn:Suden_1572 leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); SPTR: Q30Q82 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); tRNA synthetases class I (M); TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family. (823 aa) |
| | Saut_0590 | FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645; KEGG: tdn:Suden_1569 folylpolyglutamate synthetase; PRIAM: Tetrahydrofolate synthase; SPTR: P43775 Folylpolyglutamate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. (381 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (337 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | Saut_0685 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR001732; KEGG: tdn:Suden_0659 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: A2TZW0 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. (276 aa) |
| | Saut_0693 | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (332 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (158 aa) |
| | Saut_0712 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: tdn:Suden_0688 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: Q9PJ54 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrop [...] (162 aa) |
| | Saut_0726 | COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR006067:IPR005117; KEGG: nis:NIS_1436 ferredoxin--nitrite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Ferredoxin--nitrite reductase; SPTR: P39661 Ferredoxin--nitrite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain. (638 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (399 aa) |
| | trpC | COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001468; KEGG: tdn:Suden_0731 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Q30SM1 Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (267 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (366 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (253 aa) |
| | Saut_0786 | COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: tdn:Suden_1393 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: A1HN87 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (312 aa) |
| | Saut_0788 | Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (922 aa) |
| | Saut_0814 | COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: tdn:Suden_0789 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: Q9ZMX5 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (490 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (252 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | Saut_0831 | Glycosyl transferase, family 3; COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459; KEGG: tdn:Suden_1980 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 3-like; SPTR: O66585 Uncharacterized protein aq_209; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain. (297 aa) |
| | Saut_0837 | Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: tdn:Suden_1987 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: A3LHW4 Heme d1 biosynthesis protein NirJ; PFAM: Radical SAM superfamily. (373 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (368 aa) |
| | Saut_0858 | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR001597:IPR000277:IPR006235; KEGG: tdn:Suden_0765 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: O-acetylhomoserine aminocarboxypropyltransferase; SPTR: A3LJA1 Homocysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (421 aa) |
| | argG | COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: tdn:Suden_1373 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Q30QT1 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (568 aa) |
| | argH | COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR020557:IPR009049; KEGG: tdn:Suden_0866 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Q30S87 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (460 aa) |
| | Saut_0914 | Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: tdn:Suden_0868 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: C4LYI2 Putative uncharacterized protein; PFAM: HIT domain. (118 aa) |
| | pheS | COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004188:IPR002319:IPR006195:IPR004529; KEGG: tdn:Suden_0869 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; PRIAM: Phenylalanine--tRNA ligase; SPTR: Q30S84 Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class [...] (334 aa) |
| | pheT | COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR002547:IPR005121:IPR005147:IPR004532; KEGG: tdn:Suden_0870 phenylalanyl-tRNA synthetase subunit beta; PFAM: ferredoxin-fold anticodon-binding; t-RNA-binding domain protein; tRNA synthetase B5; SPTR: Q30S83 Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; glutamate--cysteine ligase [...] (778 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (276 aa) |
| | Saut_0921 | COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR002912:IPR006140:IPR006236; KEGG: tdn:Suden_0875 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; SPTR: A7IAB7 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; T [...] (528 aa) |
| | Saut_0922 | Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: tdn:Suden_1227 7-alpha-hydroxysteroid dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: P71079 Enoyl-[acyl-carrier-protein] reductase [NADPH]; PFAM: short chain dehydrogenase. (255 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | cysS | COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015413:IPR002308; KEGG: tdn:Suden_1212 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); PRIAM: Cysteine--tRNA ligase; SPTR: Q30R91 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (207 aa) |
| | Saut_0997 | Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: nis:NIS_0439 hypothetical protein; PFAM: beta-lactamase domain protein; SPTR: A3JR14 Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. (302 aa) |
| | Saut_1020 | HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: tdn:Suden_0919 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Q9HZ62 Phosphoglycolate phosphatase 2; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (210 aa) |
| | Saut_1049 | Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002489:IPR002932:IPR006982:IPR000583; KEGG: tdn:Suden_1176 glutamate synthase (NADPH) large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; PRIAM: Glutamate synthase (ferredoxin); SPTR: A2PA99 Glutamate synthase, large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1479 aa) |
| | Saut_1050 | Glutamate synthase (NADPH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759:IPR013027:IPR000103:IPR001327:IPR 006006; KEGG: tdn:Suden_1175 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A0Y0A0 Glutamate synthase, 4Fe-4S protein, small subunit; TIGRFAM: glutamate synthase, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial. (460 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa) |
| | Saut_1071 | AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020459:IPR000873; KEGG: sun:SUN_1131 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: A3U7W0 Probable long chain fatty-acid CoA ligase; PFAM: AMP-binding enzyme. (554 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (328 aa) |
| | Saut_1089 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (400 aa) |
| | Saut_1091 | Acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012000:IPR011766:IPR012001:IPR000399:IPR 012846; KEGG: tdn:Suden_1141 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; SPTR: A3EQC3 Thiamine pyrophosphate-requiring enzyme; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme [...] (565 aa) |
| | Saut_1092 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR019455:IPR002912:IPR004789; KEGG: tdn:Suden_1140 acetolactate synthase 3 regulatory subunit; PFAM: amino acid-binding ACT domain protein; Acetolactate synthase, small subunit-like; SPTR: A3JEA4 Acetolactate synthase III small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (158 aa) |
| | Saut_1095 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839; KEGG: tdn:Suden_1134 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0ZGK4 Aminotransferase, class I and II; PFAM: Aminotransferase class I and II. (390 aa) |
| | Saut_1096 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR018357:IPR005881; KEGG: tdn:Suden_1133 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: Q2NH53 Predicted serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. (233 aa) |
| | Saut_1097 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (609 aa) |
| | Saut_1098 | COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932; KEGG: tdn:Suden_1131 ferredoxin-dependent glutamate synthase; PFAM: ferredoxin-dependent glutamate synthase; SPTR: A3WNR1 Glutamate synthase, putative; PFAM: Conserved region in glutamate synthase; Belongs to the glutamate synthase family. (575 aa) |
| | hisS | COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR002314:IPR006195:IPR015807; KEGG: tdn:Suden_1130 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); PRIAM: Histidine--tRNA ligase; SPTR: Q30RH3 Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase. (404 aa) |
| | Saut_1113 | Isocitrate dehydrogenase, NADP-dependent; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: sun:SUN_0570 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A0YBV3 Isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type. (725 aa) |
| | mdh | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (318 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | glnS | COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020060:IPR018027:IPR020059:IPR020058:IPR 001412:IPR004514; KEGG: sun:SUN_1139 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; Asn/Gln amidotransferase; SPTR: A2WAW7 Glutamyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; GatB domain; TIGRFAM: glutaminyl-tRNA synthetase. (750 aa) |
| | Saut_1127 | glutamate--tRNA(Gln) ligase; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020060:IPR020058:IPR004527; KEGG: tdn:Suden_1059 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Q30RP4 Glutamyl-tRNA synthetase 2; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (423 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (647 aa) |
| | Saut_1144 | COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: tdn:Suden_1075 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A1HLR7 GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family. (153 aa) |
| | hisB | COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565; KEGG: tdn:Suden_1080 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Q30RM3 Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (190 aa) |
| | aspS | aspartate--tRNA(Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (584 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (399 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa) |
| | folD | 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa) |
| | metE | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa) |
| | Saut_1258 | COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: tdn:Suden_1028 succinate dehydrogenase/fumarate reductase subunit C; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: A1HLP7 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (293 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (349 aa) |
| | Saut_1284 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (424 aa) |
| | Saut_1294 | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: sun:SUN_1700 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Q5ZVA8 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC; PFAM: FAD dependent oxidoreductase; TIGRFAM: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain. (374 aa) |
| | glyS | COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR002311:IPR008909:IPR006194:IPR015944; KEGG: tdn:Suden_0991 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain protein; PRIAM: Glycine--tRNA ligase; SPTR: Q1CSQ2 Glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit. (672 aa) |
| | Saut_1370 | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: tdn:Suden_1254 acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Q7MAE6 Acetylornithine aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (393 aa) |
| | Saut_1397 | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: tdn:Suden_1269 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: A3LAE3 Putative uncharacterized protein; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. (449 aa) |
| | lysS | COGs: COG1190 Lysyl-tRNA synthetase (class II); InterPro IPR018149:IPR004364:IPR004365:IPR006195:IPR 002313; KEGG: tdn:Suden_1273 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: A8ESJ5 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family. (506 aa) |
| | Saut_1402 | Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR003135:IPR005482:IPR005479:IPR013651:IPR 005481:IPR011761:IPR011764; KEGG: tdn:Suden_0622 biotin carboxylase-like; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; SPTR: A6UVR2 Acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain [...] (475 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (264 aa) |
| | Saut_1414 | COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814:IPR005815; KEGG: tdn:Suden_1290 adenosylmethionine--8-amino-7-oxononanoate transaminase; PFAM: aminotransferase class-III; SPTR: A3LHM8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (127 aa) |
| | Saut_1458 | KEGG: tdn:Suden_0744 hypothetical protein; PFAM: Protein of unknown function (DUF540). (261 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (875 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | fabZ | 3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (149 aa) |
| | carB | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005483:IPR003135:IPR005479:IPR003806:IPR 011607:IPR005480:IPR005481:IPR011761:IPR006275; KEGG: tdn:Suden_1467 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; SPTR: Q9PIL7 Carbamoyl-phosphate synthase large chain; [...] (1085 aa) |
| | Saut_1511 | COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: tdn:Suden_1472 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Q9PMD4 Probable glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase. (411 aa) |
| | glmS | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa) |
| | ispDF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (374 aa) |
| | Saut_1531 | COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095:IPR006097:IPR006096; KEGG: dds:Ddes_1152 glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: P55990 NADP-specific glutamate dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa) |
| | Saut_1573 | Asparaginase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: tdn:Suden_0575 asparaginase; SPTR: B9TP42 L-asparaginase, putative; PFAM: Asparaginase. (161 aa) |
| | Saut_1597 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (319 aa) |
| | Saut_1619 | Conserved hypothetical protein; InterPro IPR000629; KEGG: tdn:Suden_1492 hypothetical protein. (141 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (224 aa) |
| | hisC | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR001917:IPR005861; KEGG: tdn:Suden_0471 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Q30TC9 Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa) |
| | Saut_1649 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912:IPR002701:IPR018528:IPR 010957; KEGG: tdn:Suden_0470 chorismate mutase, gamma, beta and epsilon; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; SPTR: A1ZLU9 P-protein; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. (360 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (403 aa) |
| | pyrB | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: tdn:Suden_0461 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Q30TD9 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TI [...] (289 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (215 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | Saut_1689 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | Saut_1702 | COGs: COG0527 Aspartokinase; InterPro IPR002912:IPR001048:IPR018042:IPR005260:IPR 001341; KEGG: tdn:Suden_1650 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: Q9ZJZ7 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (403 aa) |
| | Saut_1721 | COGs: COG0560 Phosphoserine phosphatase; InterPro IPR005834:IPR006384:IPR004469:IPR006383; KEGG: tdn:Suden_1665 phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; PRIAM: Phosphoserine phosphatase; SPTR: Q58989 Phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. (207 aa) |
| | Saut_1722 | COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tdn:Suden_1666 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: A0ZJ41 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (303 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (418 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR006063; KEGG: tdn:Suden_1673 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Q30PY1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-car [...] (236 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (246 aa) |
| | Saut_1748 | O-acetylhomoserineaminocarboxypropyltransferase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277; KEGG: tdn:Suden_0459 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: O-acetylhomoserine aminocarboxypropyltransferase; SPTR: Q0W485 O-acetyl-L-homoserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (411 aa) |
| | Saut_1754 | Peptidase dimerization domain protein; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR001261; KEGG: sun:SUN_1051 carboxypeptidase G2; PFAM: peptidase dimerisation domain protein; peptidase M20; SPTR: A0ZNS5 Putative carboxypeptidase G2; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain. (367 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (263 aa) |
| | Saut_1774 | Conserved hypothetical protein; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; KEGG: abu:Abu_0265 hypothetical protein; SPTR: P44118 Uncharacterized protein HI1169; PFAM: Aminotransferase class IV. (193 aa) |
| | Saut_1775 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: tdn:Suden_0433 cysteine synthase K/M/A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: A1HQ97 Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (516 aa) |
| | glyQ | COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; InterPro IPR002310:IPR006194; KEGG: tdn:Suden_1857 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Q30PF0 Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit. (294 aa) |
| | Saut_1811 | COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR010140; KEGG: tdn:Suden_1866 histidinol phosphate phosphatase, HisJ; PFAM: PHP domain protein; SPTR: Q9RX45 Probable histidinol-phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily. (259 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (451 aa) |
| | hisI | COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496:IPR008179; KEGG: tdn:Suden_1875 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Q7MAQ8 Histidine biosynthesis bifunctional protein hisIE; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (226 aa) |
| | ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (306 aa) |
| | Saut_1878 | COGs: COG0174 Glutamine synthetase; InterPro IPR008146:IPR008147:IPR002345:IPR004809; KEGG: sun:SUN_0353 glutamine synthase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: P94845 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (476 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (555 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (850 aa) |
| | Saut_1887 | Beta-lactamase domain protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; InterPro IPR001279; KEGG: nam:NAMH_1777 metal-dependent hydrolase of the beta-lactamase superfamily; PFAM: beta-lactamase domain protein; SPTR: Q649I9 Metal-dependent hydrolases of the beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. (232 aa) |
| | Saut_1891 | 67 kDa myosin-cross-reactive antigen family protein; COGs: COG4716 Myosin-crossreactive antigen; InterPro IPR010354; KEGG: sun:SUN_1124 myosin-cross-reactive antigen; PFAM: 67 kDa myosin-cross-reactive antigen family protein; SPTR: A3I6F1 67 kDa Myosin-crossreactive antigen; PFAM: Streptococcal 67 kDa myosin-cross-reactive antigen like family. (570 aa) |
| | Saut_1911 | COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR002912:IPR005106:IPR000634; KEGG: tdn:Suden_1904 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Q9ZL20 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain. (420 aa) |
| | Saut_1939 | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tdn:Suden_0099 pyruvate flavodoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A6UWI8 Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (318 aa) |
| | Saut_1940 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR005476:IPR002880; KEGG: tdn:Suden_0098 pyruvate flavodoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: B8D474 Pyruvate synthase subunit porA; PFAM: domain; Transketolase, C-terminal domain. (407 aa) |
| | Saut_1941 | COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR001450:IPR017900:IPR011898; KEGG: tdn:Suden_0097 pyruvate flavodoxin oxidoreductase subunit delta; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q56316 Pyruvate synthase subunit porD; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (131 aa) |
| | Saut_1942 | Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752:IPR011894; KEGG: tdn:Suden_0096 pyruvate flavodoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: O05650 Pyruvate synthase subunit porC; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. (185 aa) |
| | carA | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006220:IPR011702:IPR001317:IPR002474:IPR 000991:IPR006274; KEGG: tdn:Suden_0080 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Q7VHS5 Carbamoyl-phosphate synthase small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (379 aa) |
| | Saut_1971 | tRNA synthetase class II (G H P and S); COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR002314; KEGG: tdn:Suden_0074 ATP phosphoribosyltransferase regulatory subunit; PFAM: tRNA synthetase class II (G H P and S); SPTR: Q7MQS0 ATP phosphoribosyltransferase regulatory subunit. (282 aa) |
| | Saut_1977 | COGs: COG3420 Nitrous oxidase accessory protein; InterPro IPR006626; KEGG: sun:SUN_0158 nitrous oxidase accessory protein NosD; SPTR: A0NZJ8 Nitrous oxide maturation protein NosD; PFAM: Periplasmic copper-binding protein (NosD). (402 aa) |
| | Saut_1986 | Periplasmic copper-binding protein; COGs: COG3420 Nitrous oxidase accessory protein; InterPro IPR007742:IPR006626; KEGG: tdn:Suden_1300 periplasmic copper-binding; PFAM: periplasmic copper-binding; SPTR: A0NZJ8 Nitrous oxide maturation protein NosD; PFAM: Periplasmic copper-binding protein (NosD). (410 aa) |
| | thrS | Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR018158:IPR002314:IPR004154:IPR012947:IPR 006195:IPR002320; KEGG: tdn:Suden_0066 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Threonyl/alanyl tRNA synthetase SAD; SPTR: A8FK07 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacy [...] (602 aa) |
| | ilvD | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR020558:IPR004404; KEGG: tdn:Suden_0065 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Q30UI5 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (563 aa) |
| | anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (362 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | Saut_2040 | Ni-Fe hydrogenase, membrane subunit HyfE; COGs: COG4237 Hydrogenase 4 membrane component (E); KEGG: sun:SUN_0261 Ni-Fe hydrogenase, membrane subunit HyfE; SPTR: Q0W2B7 Hydrogenase, membrane subunit 2-like protein. (198 aa) |
| | Saut_2041 | COGs: COG0650 Formate hydrogenlyase subunit 4; KEGG: sun:SUN_0260 Ni-Fe hydrogenase, membrane subunit HycD/HyfD; SPTR: Q0W2B6 Hydrogenase, membrane subunit 3-like protein (EchB-like); PFAM: NADH dehydrogenase. (306 aa) |
| | Saut_2069 | COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932; KEGG: sun:SUN_1468 hypothetical protein; PFAM: ferredoxin-dependent glutamate synthase; SPTR: A3TY83 Glutamate synthase family protein; PFAM: Conserved region in glutamate synthase. (583 aa) |
| | Saut_2086 | Cysteine desulfurase, NifS family; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR001597:IPR000192:IPR020578:IPR017773; KEGG: tdn:Suden_2008 aminotransferase, class V; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Cysteine desulfurase; SPTR: Q9ZML2 Cysteine desulfurase; TIGRFAM: cysteine desulfurase, NifS family; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase, NifS family, epsilon proteobacteria type; cysteine desulfurase NifS. (407 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (357 aa) |
| | Saut_2111 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1162 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (252 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (539 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
