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| | purT | Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (387 aa) |
| | Saut_0046 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: tdn:Suden_0034 2-hydroxyacid dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: C4M1N2 D-glycerate dehydrogenase, putative; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (311 aa) |
| | Saut_0048 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR001041:IPR001450:IPR017900:IPR004489; KEGG: tdn:Suden_0038 succinate dehydrogenase/fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; SPTR: A3IXM6 Succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (235 aa) |
| | Saut_0089 | Aminoglycoside phosphotransferase; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: csa:Csal_0546 homoserine kinase; PFAM: aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family. (266 aa) |
| | Saut_0098 | COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: tdn:Suden_0125 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Q9ZML7 Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. (251 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (357 aa) |
| | mqnD | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (287 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (421 aa) |
| | Saut_0117 | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR001962:IPR000583:IPR006426; KEGG: tdn:Suden_0163 asparagine synthase, glutamine-hydrolyzing; PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: A3I8W6 Asparagine synthetase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (599 aa) |
| | Saut_0119 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (285 aa) |
| | Saut_0133 | Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: har:HEAR1123 putative bifunctionnal protein: glutamate-1-semialdehyde 2,1-aminomutase, 3-deoxy-manno-octulosonate cytidylyltransferase; PFAM: aminotransferase class-III; SPTR: A0Y151 Acylneuraminate cytidylyltransferase:Aminotransferase class-III; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa) |
| | Saut_0150 | Aldose 1-epimerase; COGs: COG0676 protein related to aldose 1-epimerase; InterPro IPR008183; KEGG: tdn:Suden_2076 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: B9TGM5 Aldose 1-epimerase, putative (Fragment); PFAM: Aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (277 aa) |
| | mqnA | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (216 aa) |
| | Saut_0257 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa) |
| | Saut_0258 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (192 aa) |
| | Saut_0259 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (289 aa) |
| | Saut_0260 | dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR013120:IPR002225:IPR003869:IPR001509:IPR 002198:IPR005888; KEGG: abu:Abu_1816 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; SPTR: A3J370 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glu [...] (354 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500:IPR011784; KEGG: sun:SUN_1722 sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: A6QB13 Sulfate adenylyltransferase subunit 2; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit. (303 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (479 aa) |
| | panD | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (121 aa) |
| | Saut_0302 | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tdn:Suden_0337 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: B9SYX2 Geranyl geranyl pyrophosphate synthase, putative; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (283 aa) |
| | Saut_0303 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (640 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (273 aa) |
| | Saut_0338 | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR004113:IPR006094; KEGG: tdn:Suden_0372 FAD linked oxidase-like; PFAM: FAD linked oxidase domain protein; SPTR: A1HPQ0 FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (461 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (352 aa) |
| | Saut_0352 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: tdn:Suden_0384 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7I3X0 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. (187 aa) |
| | Saut_0353 | Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: tdn:Suden_0385 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: P56074 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa) |
| | Saut_0354 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (306 aa) |
| | Saut_0359 | Conserved hypothetical protein; COGs: COG1981 membrane protein; InterPro IPR005265:IPR014351; KEGG: tdn:Suden_0391 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Q9ZJD5 UPF0093 membrane protein jhp_1377; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: conserved hypothetical integral membrane protein. (140 aa) |
| | Saut_0364 | COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: tdn:Suden_0395 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: O30000 Xanthine-guanine phosphoribosyltransferase (GptA-1); PFAM: Phosphoribosyl transferase domain. (147 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (350 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (296 aa) |
| | Saut_0387 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: tdn:Suden_1811 prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: A1HNK5 4-hydroxybenzoate polyprenyltransferase, putative; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. (286 aa) |
| | Saut_0448 | KEGG: nis:NIS_1565 hypothetical protein; PFAM: RNA helicase. (263 aa) |
| | Saut_0461 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (804 aa) |
| | Saut_0463 | COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: sun:SUN_1211 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Fructose-bisphosphate aldolase; SPTR: Q46G31 Fructose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase. (300 aa) |
| | Saut_0466 | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: sun:SUN_1452 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q8KEG7 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (400 aa) |
| | Saut_0467 | COGs: COG0058 Glucan phosphorylase; InterPro IPR000811:IPR011834; KEGG: sun:SUN_1278 glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: A0B900 Alpha-glucan phosphorylases; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases. (710 aa) |
| | Saut_0469 | COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR000173:IPR006424; KEGG: sun:SUN_1212 glyceraldehyde 3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: A7I7U0 Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, [...] (335 aa) |
| | Saut_0471 | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterPro IPR005841:IPR005844:IPR005846:IPR005843:IPR 005845:IPR016066:IPR005852; KEGG: sun:SUN_1277 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: P38569 Phosphoglucomutase; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomuta [...] (553 aa) |
| | Saut_0472 | Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005844:IPR001451:IPR005835; KEGG: sun:SUN_1275 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; SPTR: A3ILX5 Mannose-1-phosphate guanyltransferase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Nucle [...] (833 aa) |
| | Saut_0474 | 4-alpha-glucanotransferase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR015178:IPR004300:IPR015179; KEGG: sun:SUN_1273 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1925; Domain of unknown function DUF1926; PRIAM: 4-alpha-glucanotransferase; SPTR: A9QMB3 Cyclodextrin glucanotransferase; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926). (666 aa) |
| | glgA | Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (452 aa) |
| | Saut_0477 | ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sun:SUN_1270 hypothetical protein; PFAM: ROK family protein; SPTR: C3ZTK3 Putative uncharacterized protein; PFAM: ROK family. (280 aa) |
| | glgA-2 | Glycogen synthase (ADP-glucose); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (492 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (639 aa) |
| | pgi | COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: sun:SUN_1276 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Q9PMD4 Probable glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (420 aa) |
| | Saut_0483 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: sun:SUN_0970 pyruvate/2-oxoglutarate dehydrogenase complex, E1 component, alpha subunit; PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: Q6B8T2 Pyruvate dehydrogenase E1 component alpha subunit; PFAM: Dehydrogenase E1 component. (318 aa) |
| | Saut_0484 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa) |
| | Saut_0485 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR001078:IPR003016:IPR000276; KEGG: sun:SUN_1209 pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; SPTR: A3XR08 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; PFAM: 2-oxoacid dehydrogenase [...] (422 aa) |
| | Saut_0486 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR000815:IPR001327:IPR004099:IPR 012999; KEGG: sun:SUN_1208 pyruvate/2-oxoglutarate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: P54533 Dihydrolipoyl dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide ox [...] (430 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (232 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (385 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | plsX | Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa) |
| | Saut_0522 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: tdn:Suden_1764 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: A3SV40 CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (185 aa) |
| | Saut_0531 | COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR000173:IPR006424; KEGG: tdn:Suden_1754 glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: A3I3G7 Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehyd [...] (333 aa) |
| | pgk | COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911; KEGG: tdn:Suden_1753 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Q30PQ4 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (234 aa) |
| | Saut_0534 | Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347; KEGG: tdn:Suden_1751 enoyl-(acyl carrier protein) reductase; SPTR: O24990 Enoyl-[acyl-carrier-protein] reductase [NADH]; PFAM: short chain dehydrogenase. (273 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa) |
| | Saut_0554 | Pyridine nucleotide-disulfide oxidoreductase dimerization region; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR000759:IPR013027:IPR000103:IPR000815:IPR 001327:IPR004099:IPR004792:IPR012999; KEGG: rbo:A1I_07480 dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; SPTR: P11959 Dihydrolipoyl dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxi [...] (445 aa) |
| | Saut_0556 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459:IPR000873; KEGG: sun:SUN_0967 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q0W3Y0 Acetyl-CoA synthetase (AMP-forming); PFAM: AMP-binding enzyme. (583 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (322 aa) |
| | Saut_0558 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) |
| | Saut_0559 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR000089:IPR001078:IPR003016; KEGG: sun:SUN_0968 pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: A3U7G2 Dihydrolipoamide acetyltransferase component (E2) of pyruvatedehydrogenase complex; PFA [...] (385 aa) |
| | Saut_0560 | Phosphopantetheine-binding protein; InterPro IPR006163:IPR009081; KEGG: sun:SUN_0969 acyl carrier protein ACP; PFAM: phosphopantetheine-binding; SPTR: A3EU90 Acyl carrier protein; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein. (80 aa) |
| | Saut_0563 | COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR002376:IPR001555; KEGG: tdn:Suden_1617 formyl transferase-like; PFAM: formyl transferase domain protein; SPTR: A1ZQX7 Phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. (187 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (491 aa) |
| | Saut_0566 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (75 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | trpF | COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: tdn:Suden_1606 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: A6QC86 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (194 aa) |
| | Saut_0572 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: tdn:Suden_1605 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: P56188 Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (213 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (392 aa) |
| | surE | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (337 aa) |
| | Saut_0647 | COGs: COG1109 Phosphomannomutase; InterPro IPR005841:IPR005844:IPR005846:IPR005843:IPR 005845:IPR016066; KEGG: tdn:Suden_0623 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; PRIAM: Phosphomannomutase; SPTR: A3ERB6 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Ph [...] (456 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (345 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | Saut_0685 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR001732; KEGG: tdn:Suden_0659 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: A2TZW0 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. (276 aa) |
| | plsY | Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (204 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa) |
| | Saut_0704 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125:IPR004794; KEGG: tdn:Suden_0679 riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: O66534 Riboflavin biosynthesis protein ribD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. (339 aa) |
| | ubiE | Demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (241 aa) |
| | Saut_0709 | Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: tdn:Suden_0686 chlorohydrolase; PFAM: amidohydrolase; SPTR: A6UQD4 5-methylthioadenosine/S-adenosylhomocysteine deaminase; PFAM: Amidohydrolase family. (407 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (158 aa) |
| | trpC | COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001468; KEGG: tdn:Suden_0731 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Q30SM1 Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (267 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (253 aa) |
| | Saut_0786 | COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: tdn:Suden_1393 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: A1HN87 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (312 aa) |
| | Saut_0788 | Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (481 aa) |
| | Saut_0814 | COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: tdn:Suden_0789 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: Q9ZMX5 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (490 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (252 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | Saut_0826 | COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: tdn:Suden_1977 siroheme synthase CysG; PRIAM: Sirohydrochlorin ferrochelatase; SPTR: A3XKM2 Uroporphyrin-III C-methyltransferase-like; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain. (188 aa) |
| | Saut_0835 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003043:IPR006366; KEGG: tdn:Suden_1989 uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: A1HSI5 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (244 aa) |
| | Saut_0837 | Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: tdn:Suden_1987 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: A3LHW4 Heme d1 biosynthesis protein NirJ; PFAM: Radical SAM superfamily. (373 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (368 aa) |
| | Saut_0866 | AAA ATPase; InterPro IPR003593; KEGG: sun:SUN_1674 hypothetical protein; SMART: AAA ATPase; SPTR: A0XXQ3 Putative ATPase and membrane protein; PFAM: Uncharacterized conserved protein (DUF2075). (269 aa) |
| | argG | COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: tdn:Suden_1373 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Q30QT1 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | Saut_0886 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR015865:IPR002606; KEGG: tdn:Suden_1341 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SPTR: A2TY83 Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (273 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa) |
| | Saut_0904 | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tdn:Suden_0858 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: B6TA22 Decaprenyl-diphosphate synthase subunit 1; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (295 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (319 aa) |
| | Saut_0910 | COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: tdn:Suden_0864 3-octaprenyl-4hydroxybenzoate decarboxylase; PFAM: Carboxylyase-related protein; SPTR: Q9ZKF3 Uncharacterized protein jhp_0985; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. (604 aa) |
| | argH | COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR020557:IPR009049; KEGG: tdn:Suden_0866 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Q30S87 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (460 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (276 aa) |
| | Saut_0921 | COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR002912:IPR006140:IPR006236; KEGG: tdn:Suden_0875 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; SPTR: A7IAB7 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; T [...] (528 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (207 aa) |
| | Saut_0969 | COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tdn:Suden_0310 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: O25903 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (235 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (316 aa) |
| | Saut_1020 | HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: tdn:Suden_0919 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Q9HZ62 Phosphoglycolate phosphatase 2; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (210 aa) |
| | ribB | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (342 aa) |
| | Saut_1040 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (121 aa) |
| | Saut_1041 | COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: tdn:Suden_1181 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: A3IG76 Putative uncharacterized protein; PFAM: Saccharopine dehydrogenase. (392 aa) |
| | Saut_1049 | Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002489:IPR002932:IPR006982:IPR000583; KEGG: tdn:Suden_1176 glutamate synthase (NADPH) large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; PRIAM: Glutamate synthase (ferredoxin); SPTR: A2PA99 Glutamate synthase, large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1479 aa) |
| | Saut_1050 | Glutamate synthase (NADPH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759:IPR013027:IPR000103:IPR001327:IPR 006006; KEGG: tdn:Suden_1175 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A0Y0A0 Glutamate synthase, 4Fe-4S protein, small subunit; TIGRFAM: glutamate synthase, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial. (460 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (328 aa) |
| | Saut_1089 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (400 aa) |
| | Saut_1091 | Acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012000:IPR011766:IPR012001:IPR000399:IPR 012846; KEGG: tdn:Suden_1141 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; SPTR: A3EQC3 Thiamine pyrophosphate-requiring enzyme; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme [...] (565 aa) |
| | Saut_1092 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR019455:IPR002912:IPR004789; KEGG: tdn:Suden_1140 acetolactate synthase 3 regulatory subunit; PFAM: amino acid-binding ACT domain protein; Acetolactate synthase, small subunit-like; SPTR: A3JEA4 Acetolactate synthase III small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (158 aa) |
| | Saut_1095 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839; KEGG: tdn:Suden_1134 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0ZGK4 Aminotransferase, class I and II; PFAM: Aminotransferase class I and II. (390 aa) |
| | Saut_1096 | COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR018357:IPR005881; KEGG: tdn:Suden_1133 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: Q2NH53 Predicted serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. (233 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (180 aa) |
| | Saut_1107 | Aconitase; COGs: COG1049 Aconitase B; InterPro IPR015929:IPR001030:IPR018136:IPR004406; KEGG: tdn:Suden_1040 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; SPTR: Q9ZL64 Aconitate hydratase 2; TIGRFAM: aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (849 aa) |
| | Saut_1113 | Isocitrate dehydrogenase, NADP-dependent; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: sun:SUN_0570 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A0YBV3 Isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type. (725 aa) |
| | mdh | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (318 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa) |
| | Saut_1118 | 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; InterPro IPR001450:IPR017900; KEGG: tdn:Suden_1052 2-oxoglutarate-acceptor oxidoreductase subunit OorD; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8D431 2-oxoglutarate ferredoxin oxidoreductase, delta subunit. (116 aa) |
| | Saut_1119 | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: nam:NAMH_1228 OorA subunit of 2-oxoglutarate:acceptor oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A1HMJ3 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain. (384 aa) |
| | Saut_1120 | 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tdn:Suden_1054 2-oxoglutarate-acceptor oxidoreductase subunit OorB; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: O29782 2-oxoglutarate synthase subunit korB; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (285 aa) |
| | Saut_1121 | COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: sun:SUN_0581 2-oxoglutarate-acceptor oxidoreductase subunit OorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: B5IFA2 2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit, putative; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa) |
| | Saut_1127 | glutamate--tRNA(Gln) ligase; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020060:IPR020058:IPR004527; KEGG: tdn:Suden_1059 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Q30RP4 Glutamyl-tRNA synthetase 2; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (423 aa) |
| | fbp | D-fructose 1,6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR013838; KEGG: tdn:Suden_1063 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: Q30RP0 Fructose-1,6-bisphosphatase class 1; PFAM: Fructose-1-6-bisphosphatase. (280 aa) |
| | Saut_1144 | COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: tdn:Suden_1075 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A1HLR7 GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family. (153 aa) |
| | hisB | COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565; KEGG: tdn:Suden_1080 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Q30RM3 Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (190 aa) |
| | Saut_1160 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: mlo:mlr5886 hypothetical protein; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: Q12XT4 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. (211 aa) |
| | Saut_1187 | 5'-nucleotidase; InterPro IPR010394; KEGG: mmw:Mmwyl1_2729 5'-nucleotidase; PFAM: 5-nucleotidase; PRIAM: 5'-nucleotidase; SPTR: A0YDF7 5-nucleotidase; PFAM: 5'-nucleotidase. (327 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa) |
| | adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa) |
| | hemL | COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR004639; KEGG: tdn:Suden_1109 glutamate-1-semialdehyde aminotransferase; PFAM: aminotransferase class-III; SPTR: Q30RJ4 Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (431 aa) |
| | Saut_1229 | COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: tdn:Suden_1116 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: B0E8R5 Ribose-5-phosphate isomerase B, putative; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. (143 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa) |
| | metE | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa) |
| | Saut_1252 | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (275 aa) |
| | Saut_1256 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027:IPR004112:IPR006076:IPR003953:IPR 003952:IPR014006; KEGG: tdn:Suden_1030 succinate dehydrogenase/fumarate reductase subunit A; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: A3IN99 Succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarat [...] (570 aa) |
| | Saut_1257 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR017907:IPR006058:IPR001041:IPR017900:IPR 004489; KEGG: tdn:Suden_1029 succinate dehydrogenase/fumarate reductase subunit B; PRIAM: Succinate dehydrogenase; SPTR: A0ZA48 Succinate dehydrogenase; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (326 aa) |
| | Saut_1258 | COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: tdn:Suden_1028 succinate dehydrogenase/fumarate reductase subunit C; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: A1HLP7 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (293 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (349 aa) |
| | Saut_1285 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (225 aa) |
| | Saut_1370 | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: tdn:Suden_1254 acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Q7MAE6 Acetylornithine aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (393 aa) |
| | Saut_1397 | COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: tdn:Suden_1269 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: A3LAE3 Putative uncharacterized protein; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. (449 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | Saut_1407 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999:IPR006805:IPR015890; KEGG: tdn:Suden_1277 anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; PRIAM: Anthranilate synthase; SPTR: O66849 Anthranilate synthase component 1; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region. (469 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (264 aa) |
| | Saut_1409 | Phospholipase A(2); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (298 aa) |
| | Saut_1425 | Ste24 endopeptidase; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: tdn:Suden_1320 STE24 endopeptidase; PFAM: peptidase M48 Ste24p; PRIAM: Ste24 endopeptidase; SPTR: A2VRV7 Peptidase M48; PFAM: Peptidase family M48. (419 aa) |
| | gpsA | NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128:IPR006109:IPR006168; KEGG: tdn:Suden_1330 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Q30QX3 Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (295 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | Saut_1490 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | Saut_1502 | COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005476:IPR005475; KEGG: gem:GM21_3397 transketolase central region; PFAM: Transketolase central region; Transketolase domain protein; SPTR: A6UX59 Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (306 aa) |
| | Saut_1503 | COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: gem:GM21_3398 transketolase domain protein; PFAM: Transketolase domain protein; SPTR: A6UX57 Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain. (263 aa) |
| | Saut_1509 | COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR013096:IPR005835:IPR001538:IPR001468:IPR 006375; KEGG: tdn:Suden_1734 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Q8U382 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase [...] (460 aa) |
| | Saut_1511 | COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: tdn:Suden_1472 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Q9PMD4 Probable glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase. (411 aa) |
| | Saut_1512 | COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: abu:Abu_0839 UTP--glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: A3L8K6 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase. (320 aa) |
| | mqnE | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (347 aa) |
| | ispDF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (374 aa) |
| | Saut_1527 | COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: tdn:Suden_1489 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: Q0W0B9 Sulfate adenylyltransferase (Sulfurylase); PFAM: Citrate lyase ligase C-terminal domain; ATP-sulfurylase. (396 aa) |
| | Saut_1549 | Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017900; KEGG: tdn:Suden_0607 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: A1HQY5 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (427 aa) |
| | Saut_1550 | COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR010723:IPR007197:IPR006638:IPR004558; KEGG: tdn:Suden_0606 coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q9ZLH0 Oxygen-independent coproporphyrinogen-III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyri [...] (456 aa) |
| | Saut_1573 | Asparaginase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: tdn:Suden_0575 asparaginase; SPTR: B9TP42 L-asparaginase, putative; PFAM: Asparaginase. (161 aa) |
| | Saut_1577 | ATP-citrate lyase/succinyl-CoA ligase; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR005811:IPR017440; KEGG: sun:SUN_0542 ATP citrate synthase, subunit 2; PFAM: ATP-citrate lyase/succinyl-CoA ligase; SPTR: A1Y9H8 ATP citrate lyase alpha subunit (Fragment); PFAM: CoA-ligase; Citrate synthase. (604 aa) |
| | Saut_1578 | ATP citrate lyase subunit 1; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650; KEGG: tdn:Suden_0570 ATP-dependent citrate lyase beta subunit; PFAM: ATP-grasp domain protein; SPTR: A1Y9H5 ATP citrate lyase beta subunit; PFAM: ATP-grasp domain. (446 aa) |
| | Saut_1580 | COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006220:IPR011702:IPR001317:IPR000991:IPR 006221; KEGG: tdn:Suden_0568 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: P00901 Anthranilate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (188 aa) |
| | purH | IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982:IPR002695; KEGG: tdn:Suden_0550 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: A7ZCZ7 Bifunctional purine biosynthesis protein purH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHa [...] (512 aa) |
| | Saut_1597 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (319 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (738 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (308 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa) |
| | purC | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236; KEGG: tdn:Suden_0491 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Q30TB0 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (237 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (79 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (224 aa) |
| | Saut_1633 | COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tdn:Suden_0487 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: O25903 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (232 aa) |
| | Saut_1639 | Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR001176:IPR004839; KEGG: tdn:Suden_0481 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: A3J880 Aminotransferase, class I and II; PFAM: Aminotransferase class I and II. (398 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (610 aa) |
| | hisC | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR001917:IPR005861; KEGG: tdn:Suden_0471 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Q30TC9 Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa) |
| | Saut_1649 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912:IPR002701:IPR018528:IPR 010957; KEGG: tdn:Suden_0470 chorismate mutase, gamma, beta and epsilon; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; SPTR: A1ZLU9 P-protein; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2. (360 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (403 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (326 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | Saut_1689 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | Saut_1702 | COGs: COG0527 Aspartokinase; InterPro IPR002912:IPR001048:IPR018042:IPR005260:IPR 001341; KEGG: tdn:Suden_1650 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: Q9ZJZ7 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (403 aa) |
| | Saut_1704 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (351 aa) |
| | Saut_1721 | COGs: COG0560 Phosphoserine phosphatase; InterPro IPR005834:IPR006384:IPR004469:IPR006383; KEGG: tdn:Suden_1665 phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; PRIAM: Phosphoserine phosphatase; SPTR: Q58989 Phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. (207 aa) |
| | Saut_1722 | COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tdn:Suden_1666 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: A0ZJ41 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (303 aa) |
| | Saut_1730 | COGs: COG0688 Phosphatidylserine decarboxylase; KEGG: tdn:Suden_1669 putative phosphatidylserine decarboxylase; SPTR: Q39W75 Phosphatidylserine decarboxylase proenzyme; PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein. (210 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR006063; KEGG: tdn:Suden_1673 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Q30PY1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-car [...] (236 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (246 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (263 aa) |
| | Saut_1775 | COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR001216:IPR005856:IPR005859; KEGG: tdn:Suden_0433 cysteine synthase K/M/A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: A1HQ97 Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa) |
| | purD | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterPro IPR003135:IPR003806:IPR020560:IPR020562:IPR 020561:IPR011761:IPR020559:IPR000115; KEGG: tdn:Suden_0424 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Q5HTL1 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine [...] (421 aa) |
| | Saut_1785 | COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: tdn:Suden_0423 uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: A3J3E7 Uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen-III synthase HemD. (211 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa) |
| | Saut_1811 | COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR010140; KEGG: tdn:Suden_1866 histidinol phosphate phosphatase, HisJ; PFAM: PHP domain protein; SPTR: Q9RX45 Probable histidinol-phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily. (259 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (451 aa) |
| | hisI | COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496:IPR008179; KEGG: tdn:Suden_1875 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Q7MAQ8 Histidine biosynthesis bifunctional protein hisIE; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (226 aa) |
| | ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (306 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (555 aa) |
| | Saut_1911 | COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR002912:IPR005106:IPR000634; KEGG: tdn:Suden_1904 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Q9ZL20 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain. (420 aa) |
| | Saut_1933 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: tdn:Suden_1930 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: P51961 Riboflavin synthase alpha chain; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (204 aa) |
| | Saut_1939 | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tdn:Suden_0099 pyruvate flavodoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A6UWI8 Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (318 aa) |
| | Saut_1940 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR005476:IPR002880; KEGG: tdn:Suden_0098 pyruvate flavodoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: B8D474 Pyruvate synthase subunit porA; PFAM: domain; Transketolase, C-terminal domain. (407 aa) |
| | Saut_1941 | COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR001450:IPR017900:IPR011898; KEGG: tdn:Suden_0097 pyruvate flavodoxin oxidoreductase subunit delta; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q56316 Pyruvate synthase subunit porD; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (131 aa) |
| | Saut_1943 | HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: tdn:Suden_0095 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: A2SSS5 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (215 aa) |
| | ilvD | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR020558:IPR004404; KEGG: tdn:Suden_0065 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Q30UI5 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (563 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (463 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (357 aa) |
| | Saut_2111 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1162 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (252 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918:IPR000728:IPR004733; KEGG: tdn:Suden_2050 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Q21MC3 Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosyl [...] (331 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | Saut_2156 | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR019468:IPR020557:IPR004769; KEGG: tdn:Suden_2095 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: P56468 Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (443 aa) |
| | ppnP | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa) |
