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AWRI3579_g503 AWRI3579_g503 AWRI3579_g1781 AWRI3579_g1781 AWRI3579_g2441 AWRI3579_g2441 AWRI3579_g3117 AWRI3579_g3117 AWRI3579_g1995 AWRI3579_g1995 AWRI3579_g1855 AWRI3579_g1855 AWRI3579_g1677 AWRI3579_g1677 PIF1-2 PIF1-2 AWRI3579_g1069 AWRI3579_g1069 AWRI3579_g1218 AWRI3579_g1218 AWRI3579_g1504 AWRI3579_g1504 AWRI3579_g1448 AWRI3579_g1448 AWRI3579_g598 AWRI3579_g598 AWRI3579_g407 AWRI3579_g407 AWRI3579_g2018 AWRI3579_g2018 AWRI3579_g476 AWRI3579_g476 AWRI3579_g412 AWRI3579_g412 AWRI3579_g551 AWRI3579_g551 AWRI3579_g191 AWRI3579_g191 PIF1 PIF1 AWRI3579_g3955 AWRI3579_g3955 AWRI3579_g2474 AWRI3579_g2474 AWRI3579_g4251 AWRI3579_g4251 AWRI3579_g4384 AWRI3579_g4384 AWRI3579_g3575 AWRI3579_g3575 AWRI3579_g3793 AWRI3579_g3793 AWRI3579_g3749 AWRI3579_g3749 AWRI3579_g3671 AWRI3579_g3671 AWRI3579_g3153 AWRI3579_g3153 MCM7 MCM7 AWRI3579_g4561 AWRI3579_g4561 AWRI3579_g4076 AWRI3579_g4076
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AWRI3579_g503DNA helicase; Belongs to the MCM family. (980 aa)
AWRI3579_g1781Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
AWRI3579_g2441ATP-dependent DNA helicase CHL1. (869 aa)
AWRI3579_g3117ATP-dependent DNA helicase SRS2. (1078 aa)
AWRI3579_g1995DNA helicase; Belongs to the MCM family. (859 aa)
AWRI3579_g1855RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (491 aa)
AWRI3579_g1677ATP-dependent DNA helicase II subunit 1. (617 aa)
PIF1-2ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (931 aa)
AWRI3579_g1069DNA replication ATP-dependent helicase/nuclease DNA2. (1601 aa)
AWRI3579_g1218Helicase SEN1. (2178 aa)
AWRI3579_g1504Replication factor A protein 3. (152 aa)
AWRI3579_g1448ATP-dependent DNA helicase II subunit 2. (702 aa)
AWRI3579_g598DNA-dependent ATPase MGS1. (611 aa)
AWRI3579_g407Putative ATP-dependent RNA helicase ECM32. (1245 aa)
AWRI3579_g2018ATP-dependent helicase SGS1. (1330 aa)
AWRI3579_g476DNA helicase; Belongs to the MCM family. (1048 aa)
AWRI3579_g412DNA repair helicase RAD3. (778 aa)
AWRI3579_g551Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (630 aa)
AWRI3579_g191DNA helicase; Belongs to the MCM family. (1008 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (781 aa)
AWRI3579_g3955ATP-dependent helicase HRQ1. (1079 aa)
AWRI3579_g2474DNA polymerase alpha-associated DNA helicase A. (727 aa)
AWRI3579_g4251DNA repair and recombination protein RDH54. (961 aa)
AWRI3579_g4384ATP-dependent DNA helicase MER3. (1179 aa)
AWRI3579_g3575DNA repair helicase RAD25. (812 aa)
AWRI3579_g3793ATP-dependent DNA helicase HMI1, mitochondrial. (572 aa)
AWRI3579_g3749Replication factor A protein 2. (281 aa)
AWRI3579_g3671ATP-dependent DNA helicase MPH1. (1169 aa)
AWRI3579_g3153RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (461 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (859 aa)
AWRI3579_g4561DNA helicase; Belongs to the MCM family. (1032 aa)
AWRI3579_g4076Helicase SWR1. (1625 aa)
Your Current Organism:
Hanseniaspora osmophila
NCBI taxonomy Id: 56408
Other names: ATCC 24231, CBS 313, CCRC 21475, CCRC:21475, DBVPG 6795, H. osmophila, IFO 10832, KCTC 7680, Kloeckeraspora osmophila
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