STRINGSTRING
GACE_0108 GACE_0108 hemC hemC hemL hemL GACE_0111 GACE_0111 hemA hemA GACE_0152 GACE_0152 GACE_0288 GACE_0288 GACE_0319 GACE_0319 GACE_0320 GACE_0320 GACE_0398 GACE_0398 cobS cobS GACE_0518 GACE_0518 GACE_0529 GACE_0529 GACE_0567 GACE_0567 GACE_0580 GACE_0580 GACE_0625 GACE_0625 GACE_0626 GACE_0626 GACE_0627 GACE_0627 cobQ cobQ GACE_0744 GACE_0744 GACE_0753 GACE_0753 GACE_1083 GACE_1083 GACE_1084 GACE_1084 GACE_1085 GACE_1085 GACE_1086 GACE_1086 GACE_1087 GACE_1087 GACE_1088 GACE_1088 thiI thiI GACE_1090 GACE_1090 GACE_1092 GACE_1092 GACE_1093 GACE_1093 GACE_1094 GACE_1094 GACE_1095 GACE_1095 GACE_1096 GACE_1096 GACE_1097 GACE_1097 GACE_1098 GACE_1098 GACE_1100 GACE_1100 GACE_1101 GACE_1101 GACE_1102 GACE_1102 cysC cysC sat sat GACE_1206 GACE_1206 GACE_1215 GACE_1215 GACE_1217 GACE_1217 GACE_1218 GACE_1218 GACE_1219 GACE_1219 GACE_1222 GACE_1222 GACE_1223 GACE_1223 GACE_1224 GACE_1224 GACE_1225 GACE_1225 GACE_1226 GACE_1226 GACE_1260 GACE_1260 GACE_1320 GACE_1320 GACE_1358 GACE_1358 GACE_1368 GACE_1368 GACE_1483 GACE_1483 moaC moaC GACE_1547 GACE_1547 moaA moaA mobA mobA GACE_1690 GACE_1690 GACE_1738 GACE_1738 GACE_1739 GACE_1739 GACE_1757 GACE_1757 GACE_1783 GACE_1783 pyrI pyrI pyrB pyrB GACE_1786 GACE_1786 GACE_1787 GACE_1787 GACE_1788 GACE_1788 GACE_1790 GACE_1790 GACE_1791 GACE_1791 GACE_1792 GACE_1792 GACE_1793 GACE_1793 GACE_1794 GACE_1794 GACE_1795 GACE_1795 GACE_1796 GACE_1796 GACE_1798 GACE_1798 GACE_1799 GACE_1799 GACE_1800 GACE_1800 GACE_1801 GACE_1801 GACE_1802 GACE_1802 cbiN cbiN cbiM cbiM GACE_1805 GACE_1805 GACE_1806 GACE_1806 GACE_1807 GACE_1807 GACE_1851 GACE_1851 GACE_1852 GACE_1852 GACE_1853 GACE_1853 GACE_1855 GACE_1855 GACE_1856 GACE_1856 GACE_1857 GACE_1857 GACE_1858 GACE_1858 GACE_2007 GACE_2007 GACE_2169 GACE_2169
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GACE_0108Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (249 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (291 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (422 aa)
GACE_0111Porphobilinogen synthase; Belongs to the ALAD family. (302 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa)
GACE_0152Formate dehydrogenase family accessory protein FdhD. (222 aa)
GACE_0288Hypothetical protein. (105 aa)
GACE_0319Substrate-specific component BioY of biotin ECF transporter. (203 aa)
GACE_0320ABC transporter, ATP-binding protein. (356 aa)
GACE_0398Sulfur carrier protein adenylyltransferase ThiF. (251 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (241 aa)
GACE_0518Hypothetical protein. (218 aa)
GACE_0529Molybdenum cofactor biosynthesis protein MoaD. (88 aa)
GACE_0567tRNA modifying enzyme. (425 aa)
GACE_0580Hypothetical protein. (62 aa)
GACE_0625Substrate-specific component NikM of nickel ECF transporter. (294 aa)
GACE_0626Transmembrane component NikQ of energizing module of nickel ECF transporter. (243 aa)
GACE_0627ATPase component NikO of energizing module of nickel ECF transporter. (236 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (464 aa)
GACE_0744Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family. (349 aa)
GACE_0753Asparagine synthetase [glutamine-hydrolyzing]. (388 aa)
GACE_1083Aldehyde:ferredoxin oxidoreductase. (573 aa)
GACE_1084Alcohol dehydrogenase. (361 aa)
GACE_1085Hypothetical protein. (135 aa)
GACE_1086Iron-sulfur cluster assembly scaffold protein. (150 aa)
GACE_1087Cysteine desulfurase. (382 aa)
GACE_1088Rhodanese-like domain protein. (61 aa)
thiIThiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (376 aa)
GACE_1090Hypothetical protein. (308 aa)
GACE_1092Protein of unknown function DUF81. (257 aa)
GACE_1093Ferredoxin--nitrite reductase. (468 aa)
GACE_1094Hypothetical protein. (80 aa)
GACE_1095Adenylylsulfate reductase alpha-subunit. (517 aa)
GACE_1096Adenylylsulfate reductase beta-subunit. (97 aa)
GACE_1097Sulfate adenylyltransferase, dissimilatory-type. (374 aa)
GACE_1098Hypothetical protein. (126 aa)
GACE_1100Molybdopterin biosynthesis protein. (89 aa)
GACE_1101Sulfur carrier protein adenylyltransferase ThiF. (262 aa)
GACE_1102Hypothetical protein. (73 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (174 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (379 aa)
GACE_1206Molybdenum cofactor biosynthesis protein MoaE. (235 aa)
GACE_1215Thioredoxin-like protein. (77 aa)
GACE_1217Integral membrane protein. (323 aa)
GACE_1218Hypothetical protein. (340 aa)
GACE_1219Glycosyltransferase. (338 aa)
GACE_1222MolR family transcriptional regulator. (350 aa)
GACE_1223Tungstate ABC transporter, periplasmic substrate-binding protein WtpA. (345 aa)
GACE_1224Tungstate ABC transporter, permease protein WtpB. (247 aa)
GACE_1225Tungstate ABC transporter, ATP-binding protein WtpC. (344 aa)
GACE_1226Iron-sulfur cluster-binding protein. (226 aa)
GACE_1260Siroheme synthase. (230 aa)
GACE_1320Molybdenum cofactor biosynthesis protein MoaB. (169 aa)
GACE_1358Ferrous iron transport permease EfeU. (274 aa)
GACE_1368Thiamin biosynthesis protein ThiC. (426 aa)
GACE_1483Hypothetical protein. (69 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (142 aa)
GACE_1547Phosphomethylpyrimidine kinase. (450 aa)
moaAMolybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (294 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (205 aa)
GACE_1690HIT family hydrolase. (163 aa)
GACE_1738Molybdopterin biosynthesis protein MoeA. (388 aa)
GACE_1739Molybdenum cofactor biosynthesis protein MoaD. (78 aa)
GACE_1757Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (254 aa)
GACE_1783Hypothetical protein. (165 aa)
pyrIAspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (152 aa)
pyrBAspartate carbamoyltransferase. (297 aa)
GACE_1786Uroporphyrinogen-III synthase. (231 aa)
GACE_1787Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (167 aa)
GACE_1788Protein similar to polyadenylation specificity factor. (636 aa)
GACE_1790Cobalt-precorrin-6 synthase, anaerobic. (307 aa)
GACE_1791Cobalt-precorrin-8x methylmutase. (201 aa)
GACE_1792Cobalt-precorrin-3b C17-methyltransferase. (231 aa)
GACE_1793Cobalamin biosynthesis protein CbiG. (199 aa)
GACE_1794Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (235 aa)
GACE_1795Cobalt-precorrin-2 C20-methyltransferase. (196 aa)
GACE_1796Cobalt-precorrin-6y C15-methyltransferase [decarboxylating]. (179 aa)
GACE_1798Cobalt-precorrin-6y C5-methyltransferase. (182 aa)
GACE_1799Hypothetical protein. (132 aa)
GACE_1800Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (232 aa)
GACE_1801ATPase component CbiO of energizing module of cobalt ECF transporter; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (305 aa)
GACE_1802Transmembrane component CbiQ of energizing module of cobalt ECF transporter. (237 aa)
cbiNAdditional substrate-specific component CbiN of cobalt ECF transporter; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (90 aa)
cbiMSubstrate-specific component CbiM of cobalt ECF transporter; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (216 aa)
GACE_1805Cobyrinic acid A,C-diamide synthase. (424 aa)
GACE_1806Ferredoxin. (60 aa)
GACE_1807Hypothetical protein. (121 aa)
GACE_1851Hypothetical protein. (86 aa)
GACE_1852Hypothetical protein. (608 aa)
GACE_1853Hypothetical protein. (165 aa)
GACE_1855Vitamin B12 ABC transporter, permease component BtuC. (324 aa)
GACE_1856Vitamin B12 ABC transporter, ATPase component BtuD. (253 aa)
GACE_1857Adenosylcobinamide amidohydrolase. (184 aa)
GACE_1858Vitamin B12 ABC transporter, B12-binding component BtuF. (316 aa)
GACE_2007Molybdopterin biosynthesis protein MoeA. (535 aa)
GACE_2169ATP--cobalamin adenosyltransferase. (164 aa)
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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