STRINGSTRING
GACE_0250 GACE_0250 pdxT pdxT pdxS pdxS GACE_0363 GACE_0363 gap gap GACE_0805 GACE_0805 GACE_0806 GACE_0806 GACE_0807 GACE_0807 GACE_0818 GACE_0818 GACE_0934 GACE_0934 GACE_1049 GACE_1049 pgk pgk GACE_1179 GACE_1179 GACE_1230 GACE_1230 aroA-2 aroA-2 GACE_1288 GACE_1288 GACE_1418 GACE_1418 nadK nadK eno eno GACE_1758 GACE_1758 GACE_1907 GACE_1907 prs prs GACE_1913 GACE_1913 GACE_1914 GACE_1914 GACE_1915 GACE_1915 GACE_1916 GACE_1916 GACE_2065 GACE_2065 GACE_2137 GACE_2137 GACE_2145 GACE_2145 tpiA tpiA egsA egsA fbp fbp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GACE_0250Bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. (432 aa)
pdxTPyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (195 aa)
pdxSPyridoxine biosynthesis glutamine amidotransferase, synthase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (333 aa)
GACE_0363Glucose-6-phosphate isomerase. (236 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase NAD(P)-dependent, phosphorylating. (335 aa)
GACE_0805DNA mismatch repair protein MutS. (544 aa)
GACE_0806Hypothetical protein. (317 aa)
GACE_0807Ribokinase; Belongs to the carbohydrate kinase PfkB family. (297 aa)
GACE_08186-phospho-3-hexuloisomerase. (189 aa)
GACE_0934Glycerophosphoryl diester phosphodiesterase. (543 aa)
GACE_1049Fructose-bisphosphate aldolase. (182 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
GACE_1179Inositol-1-phosphate synthase. (392 aa)
GACE_1230Fructose-1,6-bisphosphate aldolase. (255 aa)
aroA-2Fructose-1,6-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa)
GACE_1288Carbohydrate kinase. (503 aa)
GACE_1418Inositol-1-monophosphatase. (255 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (258 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (400 aa)
GACE_1758Sugar phosphatase of the HAD superfamily. (266 aa)
GACE_1907CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (128 aa)
prsPhosphorybosyl pyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (277 aa)
GACE_19134-hydroxybenzoyl-CoA thioesterase. (129 aa)
GACE_1914Phosphate permease. (335 aa)
GACE_1915Phosphate transport regulator. (226 aa)
GACE_1916Phosphoglycerate mutase. (380 aa)
GACE_2065Bifunctional sugar nucleotidyltransferase/CDP-alcohol phosphatidyltransferase synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (407 aa)
GACE_2137ROK family protein. (257 aa)
GACE_2145Phosphorybosyl pyrophosphate synthase. (279 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (220 aa)
egsAGlycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (351 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (366 aa)
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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