STRINGSTRING
GACE_0136 GACE_0136 GACE_0137 GACE_0137 uppS uppS GACE_0471 GACE_0471 GACE_0595 GACE_0595 GACE_0601 GACE_0601 GACE_0651 GACE_0651 GACE_1576 GACE_1576 GACE_1692 GACE_1692 GACE_1694 GACE_1694 GACE_1860 GACE_1860 GACE_1907 GACE_1907 GACE_2008 GACE_2008 GACE_2065 GACE_2065 GACE_2118 GACE_2118 GACE_2172 GACE_2172 GACE_2173 GACE_2173 GACE_2182 GACE_2182 GACE_2183 GACE_2183 egsA egsA carS carS GACE_1665 GACE_1665 GACE_1691 GACE_1691 GACE_0053 GACE_0053 GACE_0072 GACE_0072 GACE_0093 GACE_0093 GACE_0135 GACE_0135 GACE_0690 GACE_0690 GACE_0723 GACE_0723 GACE_0724 GACE_0724 GACE_0725 GACE_0725 GACE_0747 GACE_0747 GACE_0748 GACE_0748 GACE_0750 GACE_0750 GACE_0765 GACE_0765 GACE_0766 GACE_0766 GACE_0790 GACE_0790 GACE_0791 GACE_0791 GACE_0792 GACE_0792 GACE_0794 GACE_0794 GACE_0804 GACE_0804 GACE_0822 GACE_0822 GACE_0950 GACE_0950 GACE_0951 GACE_0951 GACE_0958 GACE_0958 GACE_1175 GACE_1175 GACE_1176 GACE_1176 GACE_1179 GACE_1179 GACE_1245 GACE_1245 GACE_1287 GACE_1287 mvk mvk GACE_1301 GACE_1301 GACE_1310 GACE_1310 GACE_1316 GACE_1316 GACE_1337 GACE_1337 fni fni GACE_1413 GACE_1413 GACE_1418 GACE_1418 GACE_1500 GACE_1500 GACE_1575 GACE_1575
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GACE_0136Butyryl-CoA dehydrogenase. (378 aa)
GACE_0137Medium-chain-fatty-acid-CoA ligase. (550 aa)
uppSUndecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (243 aa)
GACE_0471Butyryl-CoA dehydrogenase. (434 aa)
GACE_0595Geranylgeranyl diphosphate reductase. (368 aa)
GACE_0601Undecaprenyl diphosphate synthase. (201 aa)
GACE_0651Medium-chain-fatty-acid--CoA ligase. (538 aa)
GACE_1576UbiA prenyltransferase. (280 aa)
GACE_1692Acetyl-CoA C-acyltransferase. (394 aa)
GACE_16943-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (652 aa)
GACE_1860Hydroxymethylglutaryl-CoA reductase. (420 aa)
GACE_1907CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (128 aa)
GACE_2008Hypothetical protein. (454 aa)
GACE_2065Bifunctional sugar nucleotidyltransferase/CDP-alcohol phosphatidyltransferase synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (407 aa)
GACE_2118Pimeloyl-CoA dehydrogenase, large subunit PimC. (397 aa)
GACE_2172Methylmalonyl-CoA mutase, N-terminal domain/subunit. (565 aa)
GACE_2173Pimeloyl-CoA dehydrogenase, small subunit PimD. (383 aa)
GACE_2182Butyryl-CoA dehydrogenase. (415 aa)
GACE_2183Medium-chain acyl-CoA ligase (alkK-3). (487 aa)
egsAGlycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (351 aa)
carSPhosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (179 aa)
GACE_1665Phytoene dehydrogenase. (386 aa)
GACE_1691Butyryl-CoA dehydrogenase. (390 aa)
GACE_0053Enoyl-CoA hydratase. (214 aa)
GACE_0072Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (390 aa)
GACE_00933-ketoacyl-CoA thiolase. (424 aa)
GACE_01353-hydroxyacyl-CoA dehydrogenase. (645 aa)
GACE_0690Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (301 aa)
GACE_07233-ketoacyl-CoA thiolase. (393 aa)
GACE_0724Butyryl-CoA dehydrogenase. (382 aa)
GACE_07253-hydroxyacyl-CoA dehydrogenase. (286 aa)
GACE_0747methylmalonyl-CoA mutase, subunit alpha, N-terminus. (548 aa)
GACE_0748methylmalonyl-CoA decarboxylase, subunit gamma. (218 aa)
GACE_0750methylmalonyl-CoA decarboxylase, subunit alpha. (518 aa)
GACE_0765Cyclohex-1-ene-1-carboxyl-CoA hydratase, BadK; Belongs to the enoyl-CoA hydratase/isomerase family. (659 aa)
GACE_07663-ketoacyl-CoA thiolase. (398 aa)
GACE_0790MaoC family protein. (147 aa)
GACE_07913-hydroxyacyl-CoA dehydrogenase. (306 aa)
GACE_0792Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
GACE_0794acetyl-CoA acetyltransferase. (391 aa)
GACE_0804Didehydro-pimeloyl-CoA hydratase, Dph. (253 aa)
GACE_0822Dehydrogenase (flavoprotein)-like protein. (322 aa)
GACE_0950CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (191 aa)
GACE_0951Phosphatidylserine decarboxylase. (188 aa)
GACE_0958Hypothetical protein. (287 aa)
GACE_11753-ketoacyl-CoA thiolase. (384 aa)
GACE_1176Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (345 aa)
GACE_1179Inositol-1-phosphate synthase. (392 aa)
GACE_1245Aldehyde dehydrogenase. (149 aa)
GACE_1287Enoyl-CoA hydratase. (251 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (293 aa)
GACE_1301Isopentenyl phosphate kinase. (235 aa)
GACE_1310Butyryl-CoA dehydrogenase. (364 aa)
GACE_1316Methylcrotonyl-CoA carboxylase biotin-containing subunit. (132 aa)
GACE_1337Hypothetical protein; Catalyzes the addition of 3 molecules of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranylgeranyl pyrophosphate (GGPP). Catalyzes the synthesis of geranylgeranyl pyrophosphate as a major product and of farnesyl pyrophosphate in smaller amounts. (319 aa)
fniIsopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (359 aa)
GACE_1413Glutaryl-CoA dehydrogenase. (398 aa)
GACE_1418Inositol-1-monophosphatase. (255 aa)
GACE_1500Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
GACE_1575(S)-3-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (228 aa)
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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