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rpl19e rpl19e rpl32e rpl32e rps19p rps19p GACE_2127 GACE_2127 GACE_2022 GACE_2022 GACE_2007 GACE_2007 purQ purQ leuC-2 leuC-2 GACE_1871 GACE_1871 GACE_1870 GACE_1870 rps17e rps17e GACE_1830 GACE_1830 leuD leuD GACE_1786 GACE_1786 pyrB pyrB GACE_1739 GACE_1739 GACE_1738 GACE_1738 GACE_1719 GACE_1719 GACE_1718 GACE_1718 GACE_1702 GACE_1702 speH-2 speH-2 GACE_1620 GACE_1620 eno eno GACE_1570 GACE_1570 rps19e rps19e rpl31e rpl31e GACE_1559 GACE_1559 guaAA guaAA GACE_1547 GACE_1547 GACE_1537 GACE_1537 GACE_1521 GACE_1521 GACE_1483 GACE_1483 GACE_1463 GACE_1463 nusA nusA speH speH rpl21e rpl21e GACE_1352 GACE_1352 rpl24e rpl24e GACE_1323 GACE_1323 GACE_1320 GACE_1320 aroA-2 aroA-2 GACE_1245 GACE_1245 GACE_1230 GACE_1230 GACE_1227 GACE_1227 GACE_1222 GACE_1222 rps3ae rps3ae GACE_1123 GACE_1123 GACE_1116 GACE_1116 GACE_1102 GACE_1102 GACE_1100 GACE_1100 GACE_1094 GACE_1094 GACE_1088 GACE_1088 GACE_1087 GACE_1087 guaAB guaAB GACE_1077 GACE_1077 GACE_1075 GACE_1075 GACE_1029 GACE_1029 GACE_1024 GACE_1024 leuC leuC rps24e rps24e GACE_0790 GACE_0790 GACE_0789 GACE_0789 GACE_0762 GACE_0762 GACE_0700 GACE_0700 GACE_0671 GACE_0671 cheB cheB GACE_0648 GACE_0648 GACE_0592 GACE_0592 dut dut purE purE GACE_0532 GACE_0532 GACE_0529 GACE_0529 GACE_0516 GACE_0516 GACE_0385 GACE_0385 GACE_0371 GACE_0371 GACE_0344 GACE_0344 GACE_0288 GACE_0288 GACE_0240 GACE_0240 GACE_0225 GACE_0225 spt5 spt5 thi4 thi4 purM purM aroA aroA rpl37ae rpl37ae rpl15e rpl15e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl19eLSU ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa)
rpl32eLSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (137 aa)
rps19pSSU ribosomal protein S15e (S19p); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa)
GACE_2127Flavodoxin, putative. (151 aa)
GACE_2022TldE protein, part of TldE/TldD proteolytic complex. (393 aa)
GACE_2007Molybdopterin biosynthesis protein MoeA. (535 aa)
purQPhosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (277 aa)
leuC-2Aconitase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (422 aa)
GACE_1871Fumarate hydratase, subunit beta. (196 aa)
GACE_1870Fumarate hydratase, subunit alpha. (273 aa)
rps17eSSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa)
GACE_1830Xanthosine/inosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (179 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (191 aa)
GACE_1786Uroporphyrinogen-III synthase. (231 aa)
pyrBAspartate carbamoyltransferase. (297 aa)
GACE_1739Molybdenum cofactor biosynthesis protein MoaD. (78 aa)
GACE_1738Molybdopterin biosynthesis protein MoeA. (388 aa)
GACE_1719Hypothetical protein. (148 aa)
GACE_1718Hypothetical protein. (132 aa)
GACE_1702Ribonucleotide-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (756 aa)
speH-2S-adenosylmethionine decarboxylase proenzyme, prokaryotic class 1B; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (135 aa)
GACE_1620RNA methylase. (233 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (400 aa)
GACE_1570Hypothetical protein. (79 aa)
rps19eSSU ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (149 aa)
rpl31eLSU ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (89 aa)
GACE_1559Hypothetical protein. (123 aa)
guaAAGMP synthase [glutamine-hydrolyzing], amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (184 aa)
GACE_1547Phosphomethylpyrimidine kinase. (450 aa)
GACE_1537Hypothetical protein. (260 aa)
GACE_1521prolyl-tRNA synthetase. (150 aa)
GACE_1483Hypothetical protein. (69 aa)
GACE_1463LSU ribosomal protein L30e. (87 aa)
nusANusA family KH domain; Participates in transcription termination. Belongs to the NusA family. (139 aa)
speHS-adenosylmethionine decarboxylase proenzyme, prokaryotic class 1B; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (114 aa)
rpl21eLSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa)
GACE_1352Phosphoglycolate phosphatase, archaeal type; Catalyzes the dephosphorylation of 2-phosphoglycolate. (221 aa)
rpl24eLSU ribosomal protein L24e; Binds to the 23S rRNA. (62 aa)
GACE_1323BioD-like N-terminal domain of phosphotransacetylase. (354 aa)
GACE_1320Molybdenum cofactor biosynthesis protein MoaB. (169 aa)
aroA-2Fructose-1,6-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa)
GACE_1245Aldehyde dehydrogenase. (149 aa)
GACE_1230Fructose-1,6-bisphosphate aldolase. (255 aa)
GACE_1227Chorismate mutase/prephenate dehydratase. (635 aa)
GACE_1222MolR family transcriptional regulator. (350 aa)
rps3aeSSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (215 aa)
GACE_1123dTDP-4-dehydrorhamnose 3,5-epimerase. (165 aa)
GACE_1116Glucose-1-phosphate thymidylyltransferase. (351 aa)
GACE_1102Hypothetical protein. (73 aa)
GACE_1100Molybdopterin biosynthesis protein. (89 aa)
GACE_1094Hypothetical protein. (80 aa)
GACE_1088Rhodanese-like domain protein. (61 aa)
GACE_1087Cysteine desulfurase. (382 aa)
guaABGMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (304 aa)
GACE_1077Hypothetical protein. (62 aa)
GACE_10753-isopropylmalate dehydratase small subunit. (135 aa)
GACE_1029rRNA methylase. (227 aa)
GACE_1024Hypothetical protein. (268 aa)
leuCAconitase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa)
rps24eSSU ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (99 aa)
GACE_0790MaoC family protein. (147 aa)
GACE_07892-ketocyclohexane-carboxyl-CoA hydrolase, BadI. (310 aa)
GACE_0762Amidohydrolase 2. (274 aa)
GACE_0700Putative ATPase (PP-loop superfamily). (292 aa)
GACE_0671Chemotaxis protein methyltransferase CheR. (267 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (328 aa)
GACE_0648Hypothetical protein. (131 aa)
GACE_0592Hypothetical protein. (58 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (167 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (156 aa)
GACE_0532Rhodanese-like domain protein. (78 aa)
GACE_0529Molybdenum cofactor biosynthesis protein MoaD. (88 aa)
GACE_0516Xylose isomerase. (254 aa)
GACE_0385Hypothetical protein. (94 aa)
GACE_0371Hypothetical protein. (156 aa)
GACE_0344Glutamine amidotransferase class-I. (220 aa)
GACE_0288Hypothetical protein. (105 aa)
GACE_0240Alkylsuccinate synthase/(1-methylalkyl) succinate synthase, catalytic subunit (AssA/MasD). (770 aa)
GACE_0225tRNA(U54)-2-thioribothymidine synthetase. (289 aa)
spt5Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (145 aa)
thi4Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (257 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (326 aa)
aroA5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (419 aa)
rpl37aeLSU ribosomal protein L37Ae; Binds to the 23S rRNA. (88 aa)
rpl15eLSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (193 aa)
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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