(36 nodes) Pyruvate metabolism network (Geoglobus acetivorans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GACE_0093	3-ketoacyl-CoA thiolase. (424 aa)
	GACE_0133	Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (676 aa)
	GACE_0215	Phosphoenolpyruvate synthase. (753 aa)
	GACE_0262	Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (295 aa)
	GACE_0283	Phosphoenolpyruvate carboxylase. (468 aa)
	GACE_0351	Beta-lactamase domain protein. (213 aa)
	GACE_0422	NADP-dependent malic enzyme. (431 aa)
	GACE_0436	2-isopropylmalate synthase. (481 aa)
	GACE_0561	Biotin carboxylase of acetyl-CoA carboxylase. (517 aa)
	GACE_0686	2-oxoacid ferredoxin oxidoreductase, subunit beta. (269 aa)
	GACE_0687	2-oxoacid ferredoxin oxidoreductase, subunit alpha. (527 aa)
	GACE_0695	Pyruvate ferredoxin oxidoreductase, beta subunit. (281 aa)
	GACE_0696	Pyruvate ferredoxin oxidoreductase, alpha subunit. (371 aa)
	GACE_0697	Pyruvate ferredoxin oxidoreductase, delta subunit. (83 aa)
	GACE_0698	Pyruvate ferredoxin oxidoreductase, gamma subunit. (162 aa)
	GACE_0723	3-ketoacyl-CoA thiolase. (393 aa)
	GACE_0766	3-ketoacyl-CoA thiolase. (398 aa)
	GACE_0768	acetyl-CoA synthetase. (460 aa)
	GACE_0769	acetyl-CoA synthetase. (197 aa)
	GACE_0794	acetyl-CoA acetyltransferase. (391 aa)
	GACE_0921	acetyl-CoA synthetase. (631 aa)
	GACE_1175	3-ketoacyl-CoA thiolase. (384 aa)
	GACE_1414	Pyruvate ferredoxin oxidoreductase, gamma subunit. (189 aa)
	GACE_1415	Pyruvate ferredoxin oxidoreductase, delta subunit. (97 aa)
	GACE_1416	Pyruvate ferredoxin oxidoreductase, alpha subunit. (387 aa)
	GACE_1417	Pyruvate ferredoxin oxidoreductase, beta subunit. (291 aa)
	GACE_1545	Oxaloacetate decarboxylase subunit alpha. (478 aa)
	GACE_1591	Acylphosphate phosphohydrolase. (90 aa)
	GACE_1621	Beta-lactamase domain protein. (209 aa)
	GACE_1692	Acetyl-CoA C-acyltransferase. (394 aa)
	GACE_1870	Fumarate hydratase, subunit alpha. (273 aa)
	GACE_1871	Fumarate hydratase, subunit beta. (196 aa)
	GACE_1962	Hypothetical protein. (204 aa)
	GACE_1990	acetyl-CoA synthetase. (678 aa)
	GACE_2153	2-ketoisovalerate ferredoxin oxidoreductase, fused subunits gamma and delta. (296 aa)
	GACE_2155	2-ketoisovalerate ferredoxin oxidoreductase, beta subunit. (275 aa)

Your Current Organism:

Geoglobus acetivorans

NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
GACE_0093	GACE_0133	3-ketoacyl-CoA thiolase.	Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative.	0.916
GACE_0093	GACE_0436	3-ketoacyl-CoA thiolase.	2-isopropylmalate synthase.	0.939
GACE_0093	GACE_0686	3-ketoacyl-CoA thiolase.	2-oxoacid ferredoxin oxidoreductase, subunit beta.	0.907
GACE_0093	GACE_0687	3-ketoacyl-CoA thiolase.	2-oxoacid ferredoxin oxidoreductase, subunit alpha.	0.909
GACE_0093	GACE_0695	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, beta subunit.	0.676
GACE_0093	GACE_0696	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, alpha subunit.	0.684
GACE_0093	GACE_0697	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, delta subunit.	0.658
GACE_0093	GACE_0698	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, gamma subunit.	0.681
GACE_0093	GACE_0723	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.613
GACE_0093	GACE_0766	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.612
GACE_0093	GACE_0768	3-ketoacyl-CoA thiolase.	acetyl-CoA synthetase.	0.916
GACE_0093	GACE_0769	3-ketoacyl-CoA thiolase.	acetyl-CoA synthetase.	0.916
GACE_0093	GACE_0794	3-ketoacyl-CoA thiolase.	acetyl-CoA acetyltransferase.	0.612
GACE_0093	GACE_0921	3-ketoacyl-CoA thiolase.	acetyl-CoA synthetase.	0.942
GACE_0093	GACE_1175	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.612
GACE_0093	GACE_1414	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, gamma subunit.	0.681
GACE_0093	GACE_1415	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, delta subunit.	0.658
GACE_0093	GACE_1416	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, alpha subunit.	0.684
GACE_0093	GACE_1417	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, beta subunit.	0.676
GACE_0093	GACE_1692	3-ketoacyl-CoA thiolase.	Acetyl-CoA C-acyltransferase.	0.610