(35 nodes) Butanoate metabolism network (Geoglobus acetivorans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GACE_0093	3-ketoacyl-CoA thiolase. (424 aa)
	GACE_0444	Acetolactate synthase small subunit. (161 aa)
	GACE_0445	Acetolactate synthase large subunit. (555 aa)
	GACE_0594	4-hydroxyphenylacetate 3-monooxygenase. (461 aa)
	GACE_0686	2-oxoacid ferredoxin oxidoreductase, subunit beta. (269 aa)
	GACE_0687	2-oxoacid ferredoxin oxidoreductase, subunit alpha. (527 aa)
	GACE_0695	Pyruvate ferredoxin oxidoreductase, beta subunit. (281 aa)
	GACE_0696	Pyruvate ferredoxin oxidoreductase, alpha subunit. (371 aa)
	GACE_0697	Pyruvate ferredoxin oxidoreductase, delta subunit. (83 aa)
	GACE_0698	Pyruvate ferredoxin oxidoreductase, gamma subunit. (162 aa)
	GACE_0723	3-ketoacyl-CoA thiolase. (393 aa)
	GACE_0725	3-hydroxyacyl-CoA dehydrogenase. (286 aa)
	GACE_0766	3-ketoacyl-CoA thiolase. (398 aa)
	GACE_0791	3-hydroxyacyl-CoA dehydrogenase. (306 aa)
	GACE_0792	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
	GACE_0794	acetyl-CoA acetyltransferase. (391 aa)
	GACE_1175	3-ketoacyl-CoA thiolase. (384 aa)
	GACE_1176	Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (345 aa)
	GACE_1272	Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (555 aa)
	GACE_1311	Glutaconate CoA-transferase subunit B. (257 aa)
	GACE_1312	Glutaconate CoA-transferase subunit A. (320 aa)
	GACE_1316	Methylcrotonyl-CoA carboxylase biotin-containing subunit. (132 aa)
	GACE_1414	Pyruvate ferredoxin oxidoreductase, gamma subunit. (189 aa)
	GACE_1415	Pyruvate ferredoxin oxidoreductase, delta subunit. (97 aa)
	GACE_1416	Pyruvate ferredoxin oxidoreductase, alpha subunit. (387 aa)
	GACE_1417	Pyruvate ferredoxin oxidoreductase, beta subunit. (291 aa)
	GACE_1499	4-hydroxyphenylacetate 3-monooxygenase. (475 aa)
	GACE_1500	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
	GACE_1692	Acetyl-CoA C-acyltransferase. (394 aa)
	GACE_2122	Succinate dehydrogenase, subunit A. (568 aa)
	GACE_2123	Succinate dehydrogenase, subunit B. (238 aa)
	GACE_2124	Succinate dehydrogenase, subunit C. (125 aa)
	GACE_2125	Succinate dehydrogenase, subunit D. (116 aa)
	GACE_2153	2-ketoisovalerate ferredoxin oxidoreductase, fused subunits gamma and delta. (296 aa)
	GACE_2155	2-ketoisovalerate ferredoxin oxidoreductase, beta subunit. (275 aa)

Your Current Organism:

Geoglobus acetivorans

NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
GACE_0093	GACE_0686	3-ketoacyl-CoA thiolase.	2-oxoacid ferredoxin oxidoreductase, subunit beta.	0.907
GACE_0093	GACE_0687	3-ketoacyl-CoA thiolase.	2-oxoacid ferredoxin oxidoreductase, subunit alpha.	0.909
GACE_0093	GACE_0695	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, beta subunit.	0.676
GACE_0093	GACE_0696	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, alpha subunit.	0.684
GACE_0093	GACE_0697	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, delta subunit.	0.658
GACE_0093	GACE_0698	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, gamma subunit.	0.681
GACE_0093	GACE_0723	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.613
GACE_0093	GACE_0725	3-ketoacyl-CoA thiolase.	3-hydroxyacyl-CoA dehydrogenase.	0.992
GACE_0093	GACE_0766	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.612
GACE_0093	GACE_0791	3-ketoacyl-CoA thiolase.	3-hydroxyacyl-CoA dehydrogenase.	0.982
GACE_0093	GACE_0792	3-ketoacyl-CoA thiolase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.908
GACE_0093	GACE_0794	3-ketoacyl-CoA thiolase.	acetyl-CoA acetyltransferase.	0.612
GACE_0093	GACE_1175	3-ketoacyl-CoA thiolase.	3-ketoacyl-CoA thiolase.	0.612
GACE_0093	GACE_1176	3-ketoacyl-CoA thiolase.	Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.	0.990
GACE_0093	GACE_1311	3-ketoacyl-CoA thiolase.	Glutaconate CoA-transferase subunit B.	0.457
GACE_0093	GACE_1312	3-ketoacyl-CoA thiolase.	Glutaconate CoA-transferase subunit A.	0.420
GACE_0093	GACE_1414	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, gamma subunit.	0.681
GACE_0093	GACE_1415	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, delta subunit.	0.658
GACE_0093	GACE_1416	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, alpha subunit.	0.684
GACE_0093	GACE_1417	3-ketoacyl-CoA thiolase.	Pyruvate ferredoxin oxidoreductase, beta subunit.	0.676