125 items (Leishmania braziliensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LBRM_01_0470	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (200 aa)
	LBRM_02_0640	Uncharacterized protein. (906 aa)
	LBRM_03_0590	Uncharacterized protein. (2207 aa)
	LBRM_03_0810	Putative peter pan protein. (372 aa)
	LBRM_04_0170	Putative exosome complex exonuclease RRP40. (300 aa)
	LbrM04_V2.0780	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (670 aa)
	LBRM_05_0200	CP-type G domain-containing protein. (788 aa)
	LBRM_05_0470	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (640 aa)
	LBRM_07_0490	Uncharacterized protein. (780 aa)
	LBRM_08_0470	Uncharacterized protein. (1400 aa)
	LBRM_09_0020	Uncharacterized protein. (373 aa)
	LBRM_10_0210	Putative nucleolar protein. (471 aa)
	LBRM_10_0830	Uncharacterized protein. (943 aa)
	LBRM_10_1130	RNA-binding protein-like protein. (390 aa)
	LbrM11_V2.0090	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (743 aa)
	LBRM_11_0230	WD_REPEATS_REGION domain-containing protein. (680 aa)
	LBRM_11_0550	Putative 40S ribosomal protein S21. (165 aa)
	LBRM_13_0390	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (141 aa)
	LBRM_13_0500	Peptidase_M24 domain-containing protein. (534 aa)
	LBRM_13_1360	WD_REPEATS_REGION domain-containing protein. (758 aa)
	LBRM_14_0010	Putative exosome complex exonuclease. (303 aa)
	LBRM_14_0420	Uncharacterized protein. (1068 aa)
	LBRM_14_0550	Uncharacterized protein. (1156 aa)
	LBRM_15_0130	Putative ATP-dependent RNA helicase. (683 aa)
	LBRM_15_1380	Putative nucleolar RNA binding protein. (444 aa)
	LBRM_16_0060	Uncharacterized protein. (657 aa)
	LBRM_16_0890	Uncharacterized protein. (662 aa)
	LBRM_16_1450	Uncharacterized protein. (287 aa)
	LBRM_17_1410	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1080 aa)
	LBRM_17_1500	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (865 aa)
	LBRM_18_0920	Periodic tryptophan protein 2-like protein. (942 aa)
	LBRM_18_1000	Uncharacterized protein. (120 aa)
	LBRM_18_1020	Uncharacterized protein. (1268 aa)
	LBRM_18_1640	Uncharacterized protein. (654 aa)
	LBRM_19_0410	Putative fibrillarin. (433 aa)
	LBRM_19_0710	Putative 40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	LBRM_19_0990	Putative U3 snoRNA-associated protein UTP11. (360 aa)
	LBRM_19_1360	PINc domain-containing protein. (209 aa)
	LBRM_20_0670	Contig, possible fusion of chromosomes 20 and 34. (468 aa)
	RH	RH protein. (775 aa)
	RH-2	RH protein. (772 aa)
	LBRM_20_1540	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (803 aa)
	LBRM_20_2300	Contig, possible fusion of chromosomes 20 and 34. (425 aa)
	LBRM_20_2660	Contig, possible fusion of chromosomes 20 and 34. (735 aa)
	LBRM_22_1260	Protein MAK16 homolog; Belongs to the MAK16 family. (268 aa)
	LBRM_22_1490	Putative exosome complex exonuclease RRP45 homolog. (363 aa)
	LBRM_23_0040	Putative beta propeller protein. (478 aa)
	LBRM_23_0570	Ribosomal RNA methyltransferase-like protein. (285 aa)
	LBRM_23_1670	Putative Csl4p homologue. (281 aa)
	LBRM_24_0240	Putative ATP-dependent RNA helicase. (606 aa)
	LBRM_24_1360	WD_REPEATS_REGION domain-containing protein. (444 aa)
	LBRM_24_2340	Putative notchless homolog. (522 aa)
	LBRM_25_0380	Uncharacterized protein. (968 aa)
	PUF8	PUF8 protein. (577 aa)
	LbrM_25_2590	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (842 aa)
	LBRM_26_0030	Brix domain containing-like protein. (362 aa)
	LBRM_26_1270	Uncharacterized protein. (699 aa)
	LBRM_26_1720	Uncharacterized protein. (2767 aa)
	LBRM_27_0060	RNA helicase. (690 aa)
	LBRM_27_0540	Ribosome biogenesis protein. (330 aa)
	LBRM_27_1590	CBF domain-containing protein. (855 aa)
	LBRM_27_2160	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (927 aa)
	LBRM_27_2430	Uncharacterized protein. (246 aa)
	LBRM_28_0340	Putative rrp44p homologue; Belongs to the RNR ribonuclease family. (920 aa)
	LBRM_28_0460	Putative ribonuclease II-like protein; Belongs to the RNR ribonuclease family. (929 aa)
	LBRM_28_0480	WD_REPEATS_REGION domain-containing protein. (795 aa)
	LBRM_28_0750	Sas10 domain-containing protein. (551 aa)
	LBRM_28_1410	Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (897 aa)
	LBRM_28_2050	Bms1-type G domain-containing protein. (1256 aa)
	LBRM_29_0770	Putative U3 small nucleolar ribonucleoprotein protein MPP10. (682 aa)
	LBRM_29_1450	Uncharacterized protein. (621 aa)
	LBRM_29_2030	Uncharacterized protein. (1093 aa)
	LBRM_30_0220	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (366 aa)
	LBRM_30_0560	Putative bystin. (469 aa)
	LBRM_30_0700	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (216 aa)
	LBRM_30_1420	Putative U3 small nuclear ribonucleoprotein (SnRNP). (288 aa)
	LBRM_30_1480	RIO domain-containing protein. (486 aa)
	LBRM_30_3000	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (322 aa)
	LBRM_30_3290	Putative ATP-dependent RNA helicase. (1026 aa)
	LBRM_31_0300	Putative nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (625 aa)
	LBRM_31_0310	WD_REPEATS_REGION domain-containing protein. (448 aa)
	LBRM_31_1210	Uncharacterized protein. (753 aa)
	LBRM_31_2660	WD_REPEATS_REGION domain-containing protein. (482 aa)
	LBRM_31_3350	SMK-1 domain-containing protein. (988 aa)
	LBRM_32_0210	Uncharacterized protein. (993 aa)
	LBRM_32_0650	Putative RNA helicase. (584 aa)
	LBRM_32_0770	Uncharacterized protein. (63 aa)
	LBRM_32_2450	RNA helicase. (770 aa)
	LBRM_32_3050	Putative RNA-binding protein. (446 aa)
	LBRM_32_3750	Putative exosome-associated protein 2. (312 aa)
	LBRM_33_1620	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (181 aa)
	LBRM_33_2140	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (652 aa)
	LBRM_33_2190	WD_REPEATS_REGION domain-containing protein. (584 aa)
	LBRM_33_2430	WD_REPEATS_REGION domain-containing protein. (867 aa)
	LBRM_33_2680	Putative ras-like small GTPases. (565 aa)
	LBRM_33_2800	NUC173 domain-containing protein. (1299 aa)
	LBRM_34_0660	Uncharacterized protein. (4181 aa)
	LBRM_34_1610	Putative RNA 3'-terminal phosphate cyclase. (362 aa)
	LBRM_34_1730	Uncharacterized protein. (273 aa)
	LBRM_34_1900	Uncharacterized protein. (1058 aa)
	LBRM_34_2420	Uncharacterized protein. (340 aa)
	LBRM_34_2900	Uncharacterized protein. (412 aa)
	LBRM_34_3470	KH domain-containing protein. (221 aa)
	LBRM_34_3860	WD_REPEATS_REGION domain-containing protein. (444 aa)
	LBRM_34_4010	RNA helicase. (691 aa)
	LBRM_35_2030	Putative DEAD box RNA helicase; Belongs to the DEAD box helicase family. (654 aa)
	LBRM_35_2070	Uncharacterized protein. (633 aa)
	LBRM_35_3220	Putative ATP-dependent RNA helicase. (954 aa)
	LBRM_35_3240	Putative exosome complex exonuclease rrp41. (246 aa)
	LBRM_35_3290	Fibrillarin. (233 aa)
	LBRM_35_3880	Uncharacterized protein. (393 aa)
	LBRM_35_4460	Uncharacterized protein. (987 aa)
	LBRM_35_4640	ATP-dependent RNA helicase-like protein. (974 aa)
	LBRM_35_4830	Uncharacterized protein. (452 aa)
	LBRM_35_4900	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (227 aa)
	LBRM_35_5140	Putative exosome-associated protein 4. (221 aa)
	LBRM_35_5310	Uncharacterized protein; Belongs to the NOB1 family. (440 aa)
	LBRM_35_6730	Putative 40S ribosomal protein S8. (260 aa)
	LBRM_35_6860	Uncharacterized protein. (700 aa)
	LBRM_35_7290	Uncharacterized protein. (268 aa)
	LBRM_20_4880	Contig, possible fusion of chromosomes 20 and 34. (742 aa)
	LBRM_20_5100	Contig, possible fusion of chromosomes 20 and 34. (598 aa)
	LBRM_20_5570	Contig, possible fusion of chromosomes 20 and 34. (403 aa)
	LBRM_20_5830	Contig, possible fusion of chromosomes 20 and 34. (316 aa)
	LBRM_31_0820	FtsJ domain-containing protein. (331 aa)

Your Current Organism:

Leishmania braziliensis

NCBI taxonomy Id: 5660
Other names: L. braziliensis, Leishmania (V.) braziliensis, Leishmania (Viannia) braziliensis, Leishmania brasiliensis, Leishmania viannia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LBRM_01_0470	LBRM_02_0640	A4H368	A4H3F7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.932
LBRM_01_0470	LBRM_03_0590	A4H368	A4H3N0	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.617
LBRM_01_0470	LBRM_04_0170	A4H368	A4H3T3	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative exosome complex exonuclease RRP40.	0.720
LBRM_01_0470	LBRM_07_0490	A4H368	A4H4Z3	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.924
LBRM_01_0470	LBRM_10_0210	A4H368	A4H602	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative nucleolar protein.	0.945
LBRM_01_0470	LBRM_11_0230	A4H368	A4H6H1	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	WD_REPEATS_REGION domain-containing protein.	0.934
LBRM_01_0470	LBRM_11_0550	A4H368	A4H6K1	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative 40S ribosomal protein S21.	0.992
LBRM_01_0470	LBRM_13_0390	A4H368	A4H746	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.988
LBRM_01_0470	LBRM_13_0500	A4H368	A4H757	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Peptidase_M24 domain-containing protein.	0.589
LBRM_01_0470	LBRM_13_1360	A4H368	A4H7E0	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	WD_REPEATS_REGION domain-containing protein.	0.933
LBRM_01_0470	LBRM_14_0010	A4H368	A4H7G3	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative exosome complex exonuclease.	0.732
LBRM_01_0470	LBRM_14_0550	A4H368	A4H7L4	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.839
LBRM_01_0470	LBRM_15_1380	A4H368	A4H8A6	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative nucleolar RNA binding protein.	0.944
LBRM_01_0470	LBRM_16_1450	A4H368	A4H8R8	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.897
LBRM_01_0470	LBRM_17_1410	A4H368	A4H984	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.833
LBRM_01_0470	LBRM_18_0920	A4H368	A4H9J4	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Periodic tryptophan protein 2-like protein.	0.939
LBRM_01_0470	LBRM_18_1000	A4H368	A4H9K2	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.882
LBRM_01_0470	LBRM_18_1020	A4H368	A4H9K4	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Uncharacterized protein.	0.882
LBRM_01_0470	LBRM_19_0410	A4H368	A4H9W7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative fibrillarin.	0.894
LBRM_01_0470	LBRM_19_0710	A4H368	A4H9Z7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	Putative 40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.999

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