(15 nodes) Anaphase-promoting complex network (Leishmania major)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LMJF_35_3750	CULLIN_2 domain-containing protein; Belongs to the cullin family. (875 aa)
	LMJF_35_4500	Putative anaphase promoting complex subunit protein. (82 aa)
	LMJF_36_2035	WD_REPEATS_REGION domain-containing protein. (682 aa)
	LMJF_33_2770	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (243 aa)
	LMJF_33_0370	WD_REPEATS_REGION domain-containing protein. (728 aa)
	LMJF_30_1990	Cyclosome subunit-like protein. (2162 aa)
	LMJF_30_0710	Putative CDC16. (546 aa)
	LMJF_26_0370	Uncharacterized protein. (853 aa)
	LMJF_24_2130	Putative ubiquitin-conjugating enzyme e2; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)
	LMJF_24_1720	Putative cell division cycle protein. (838 aa)
	LMJF_16_0650	RING-type domain-containing protein. (105 aa)
	LMJF_15_0710	Uncharacterized protein. (3115 aa)
	LMJF_12_0610	TPR_REGION domain-containing protein. (1025 aa)
	LMJF_05_0410	TPR_REGION domain-containing protein. (920 aa)
	LMJF_04_0400	Anaphase promoting complex, subunit 10-like protein. (340 aa)

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LMJF_04_0400	LMJF_05_0410	Q9U198	Q4QJG1	Anaphase promoting complex, subunit 10-like protein.	TPR_REGION domain-containing protein.	0.952
LMJF_04_0400	LMJF_12_0610	Q9U198	Q4QGN2	Anaphase promoting complex, subunit 10-like protein.	TPR_REGION domain-containing protein.	0.980
LMJF_04_0400	LMJF_15_0710	Q9U198	Q4QFB4	Anaphase promoting complex, subunit 10-like protein.	Uncharacterized protein.	0.901
LMJF_04_0400	LMJF_16_0650	Q9U198	Q4QEV4	Anaphase promoting complex, subunit 10-like protein.	RING-type domain-containing protein.	0.952
LMJF_04_0400	LMJF_24_1720	Q9U198	Q4QAF9	Anaphase promoting complex, subunit 10-like protein.	Putative cell division cycle protein.	0.903
LMJF_04_0400	LMJF_24_2130	Q9U198	Q4QAB7	Anaphase promoting complex, subunit 10-like protein.	Putative ubiquitin-conjugating enzyme e2; Belongs to the ubiquitin-conjugating enzyme family.	0.831
LMJF_04_0400	LMJF_26_0370	Q9U198	Q4Q9F4	Anaphase promoting complex, subunit 10-like protein.	Uncharacterized protein.	0.733
LMJF_04_0400	LMJF_30_0710	Q9U198	Q4Q7N6	Anaphase promoting complex, subunit 10-like protein.	Putative CDC16.	0.980
LMJF_04_0400	LMJF_30_1990	Q9U198	Q4Q795	Anaphase promoting complex, subunit 10-like protein.	Cyclosome subunit-like protein.	0.980
LMJF_04_0400	LMJF_33_0370	Q9U198	Q4Q4H0	Anaphase promoting complex, subunit 10-like protein.	WD_REPEATS_REGION domain-containing protein.	0.903
LMJF_04_0400	LMJF_33_2770	Q9U198	Q4Q3Q8	Anaphase promoting complex, subunit 10-like protein.	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.785
LMJF_04_0400	LMJF_35_3750	Q9U198	E9AFJ9	Anaphase promoting complex, subunit 10-like protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.980
LMJF_04_0400	LMJF_35_4500	Q9U198	E9AFS7	Anaphase promoting complex, subunit 10-like protein.	Putative anaphase promoting complex subunit protein.	0.952
LMJF_04_0400	LMJF_36_2035	Q9U198	Q4Q1L9	Anaphase promoting complex, subunit 10-like protein.	WD_REPEATS_REGION domain-containing protein.	0.903
LMJF_05_0410	LMJF_04_0400	Q4QJG1	Q9U198	TPR_REGION domain-containing protein.	Anaphase promoting complex, subunit 10-like protein.	0.952
LMJF_05_0410	LMJF_12_0610	Q4QJG1	Q4QGN2	TPR_REGION domain-containing protein.	TPR_REGION domain-containing protein.	0.981
LMJF_05_0410	LMJF_16_0650	Q4QJG1	Q4QEV4	TPR_REGION domain-containing protein.	RING-type domain-containing protein.	0.952
LMJF_05_0410	LMJF_24_1720	Q4QJG1	Q4QAF9	TPR_REGION domain-containing protein.	Putative cell division cycle protein.	0.932
LMJF_05_0410	LMJF_24_2130	Q4QJG1	Q4QAB7	TPR_REGION domain-containing protein.	Putative ubiquitin-conjugating enzyme e2; Belongs to the ubiquitin-conjugating enzyme family.	0.863
LMJF_05_0410	LMJF_26_0370	Q4QJG1	Q4Q9F4	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.540