26 items (Leishmania major) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	LMJF_27_0450	Ribosome biogenesis protein. (330 aa)
	LMJF_27_1450	CBF domain-containing protein. (853 aa)
	LMJF_27_1980	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (924 aa)
	LMJF_35_1820	Uncharacterized protein. (273 aa)
	LmjF22.0030	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (671 aa)
	LMJF_36_6920	Uncharacterized protein. (275 aa)
	LMJF_36_6400	Putative 40S ribosomal protein S8. (260 aa)
	LMJF_36_4650	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (227 aa)
	LMJF_36_1880	Uncharacterized protein. (634 aa)
	LMJF_33_2400	Putative ras-like small GTPases. (567 aa)
	LMJF_33_1870	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (652 aa)
	LMJF_33_1350	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (181 aa)
	LMJF_31_0200	WD_REPEATS_REGION domain-containing protein. (485 aa)
	LMJF_31_0190	Putative nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (629 aa)
	LMJF_30_0620	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (245 aa)
	LMJF_26_0010	Brix domain containing-like protein. (362 aa)
	LMJF_25_1500	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (708 aa)
	LMJF_22_1380	Protein MAK16 homolog; Belongs to the MAK16 family. (267 aa)
	LMJF_20_1670	Putative ribosome biogenesis protein. (317 aa)
	LMJF_18_1610	Uncharacterized protein. (654 aa)
	LMJF_16_0890	Uncharacterized protein. (662 aa)
	LmjF11.0410	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (808 aa)
	LMJF_10_1030	RNA-binding protein-like protein. (379 aa)
	LMJF_09_0005	Uncharacterized protein. (373 aa)
	LMJF_05_0460	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (627 aa)
	P883.41	FtsJ-like methyltransferase. (335 aa)

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LMJF_05_0460	LMJF_09_0005	Q4QJF6	Q4QI35	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.912
LMJF_05_0460	LMJF_10_1030	Q4QJF6	Q4QHB1	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	RNA-binding protein-like protein.	0.985
LMJF_05_0460	LMJF_16_0890	Q4QJF6	Q4QET0	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.776
LMJF_05_0460	LMJF_18_1610	Q4QJF6	Q4QDM8	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.889
LMJF_05_0460	LMJF_20_1670	Q4QJF6	Q4QCN5	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Putative ribosome biogenesis protein.	0.883
LMJF_05_0460	LMJF_22_1380	Q4QJF6	Q4QBK9	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.852
LMJF_05_0460	LMJF_25_1500	Q4QJF6	Q4Q9U1	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.787
LMJF_05_0460	LMJF_26_0010	Q4QJF6	Q4Q9J0	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Brix domain containing-like protein.	0.989
LMJF_05_0460	LMJF_27_0450	Q4QJF6	E9AD22	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Ribosome biogenesis protein.	0.792
LMJF_05_0460	LMJF_27_1450	Q4QJF6	E9ADC6	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	CBF domain-containing protein.	0.881
LMJF_05_0460	LMJF_27_1980	Q4QJF6	E9ADH8	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.866
LMJF_05_0460	LMJF_30_0620	Q4QJF6	Q4Q7P4	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.974
LMJF_05_0460	LMJF_31_0190	Q4QJF6	Q4Q6P5	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Putative nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.787
LMJF_05_0460	LMJF_31_0200	Q4QJF6	Q4Q6P4	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.943
LMJF_05_0460	LMJF_33_1350	Q4QJF6	Q4Q453	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.871
LMJF_05_0460	LMJF_33_1870	Q4QJF6	Q4Q401	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.999
LMJF_05_0460	LMJF_33_2400	Q4QJF6	Q4Q3U7	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Putative ras-like small GTPases.	0.987
LMJF_05_0460	LMJF_35_1820	Q4QJF6	E9AF03	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.956
LMJF_05_0460	LMJF_36_1880	Q4QJF6	Q4Q1N6	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.929
LMJF_05_0460	LMJF_36_4650	Q4QJF6	Q4Q0U9	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.984