STRINGSTRING
LMJF_18_1450 LMJF_18_1450 LMJF_18_1610 LMJF_18_1610 LMJF_19_0100 LMJF_19_0100 LMJF_19_0420 LMJF_19_0420 LMJF_19_0660 LMJF_19_0660 LMJF_19_1210 LMJF_19_1210 LMJF_20_0420 LMJF_20_0420 LMJF_20_0650 LMJF_20_0650 LMJF_20_0920 LMJF_20_0920 LMJF_20_1360 LMJF_20_1360 LMJF_20_1670 LMJF_20_1670 LMJF_27_0050 LMJF_27_0050 LMJF_27_2250 LMJF_27_2250 LMJF_32_0570 LMJF_32_0570 LMJF_32_0690 LMJF_32_0690 LMJF_32_3460 LMJF_32_3460 LMJF_33_0235 LMJF_33_0235 LMJF_33_1350 LMJF_33_1350 LMJF_33_1870 LMJF_33_1870 LMJF_33_1910 LMJF_33_1910 LMJF_22_1380 LMJF_22_1380 LMJF_23_0030 LMJF_23_0030 LMJF_23_0290 LMJF_23_0290 LMJF_24_0250 LMJF_24_0250 LMJF_24_0540 LMJF_24_0540 LMJF_24_0550 LMJF_24_0550 AIP1 AIP1 LMJF_25_0140 LMJF_25_0140 LMJF_25_0430 LMJF_25_0430 LMJF_25_0620 LMJF_25_0620 PUF8 PUF8 LMJF_26_0010 LMJF_26_0010 LMJF_27_0450 LMJF_27_0450 LMJF_27_1980 LMJF_27_1980 LMJF_29_0750 LMJF_29_0750 LMJF_29_1400 LMJF_29_1400 LMJF_35_1090 LMJF_35_1090 LMJF_35_1400 LMJF_35_1400 LMJF_35_1820 LMJF_35_1820 LMJF_35_1990 LMJF_35_1990 LMJF_35_2480 LMJF_35_2480 LMJF_35_2990 LMJF_35_2990 LMJF_35_3540 LMJF_35_3540 LMJF_21_1230 LMJF_21_1230 LMJF_35_3880 LMJF_35_3880 LMJF_35_4030 LMJF_35_4030 LmjF22.0030 LmjF22.0030 RPS8A RPS8A FEN1 FEN1 LMJF_36_6520 LMJF_36_6520 LMJF_28_0720 LMJF_28_0720 LMJF_28_0470 LMJF_28_0470 LMJF_28_0120 LMJF_28_0120 LMJF_26_1790 LMJF_26_1790 LMJF_26_1250 LMJF_26_1250 LMJF_26_0490 LMJF_26_0490 L374.02 L374.02 L6586.01 L6586.01 LMJF_04_0120 LMJF_04_0120 L8530.04 L8530.04 P883.41 P883.41 LMJF_36_6400 LMJF_36_6400 LMJF_36_4895 LMJF_36_4895 LMJF_36_4710 LMJF_36_4710 LMJF_36_4650 LMJF_36_4650 LMJF_36_4580 LMJF_36_4580 LMJF_36_4400 LMJF_36_4400 LMJF_36_4210 LMJF_36_4210 LMJF_36_3650 LMJF_36_3650 LMJF_36_3070 LMJF_36_3070 LMJF_36_3020 LMJF_36_3020 LMJF_36_1880 LMJF_36_1880 LMJF_05_0360 LMJF_05_0360 LMJF_05_0460 LMJF_05_0460 LMJF_05_0660 LMJF_05_0660 LMJF_06_1020 LMJF_06_1020 LMJF_07_0470 LMJF_07_0470 LMJF_07_0580 LMJF_07_0580 LMJF_07_0700 LMJF_07_0700 LMJF_09_0005 LMJF_09_0005 LMJF_10_0100 LMJF_10_0100 LMJF_10_0210 LMJF_10_0210 LMJF_10_0483 LMJF_10_0483 LMJF_10_0700 LMJF_10_0700 LMJF_10_1030 LMJF_10_1030 LMJF_11_0190 LMJF_11_0190 LmjF11.0410 LmjF11.0410 LMJF_11_0900 LMJF_11_0900 LMJF_12_0570 LMJF_12_0570 LMJF_12_0590 LMJF_12_0590 RPL18-A RPL18-A LMJF_13_1120 LMJF_13_1120 LMJF_14_0260 LMJF_14_0260 LMJF_14_0410 LMJF_14_0410 LMJF_14_0570 LMJF_14_0570 LMJF_14_1240 LMJF_14_1240 LMJF_15_0130 LMJF_15_0130 LMJF_15_1380 LMJF_15_1380 LMJF_15_1470 LMJF_15_1470 LMJF_16_0050 LMJF_16_0050 LMJF_16_1350 LMJF_16_1350 LMJF_16_1390 LMJF_16_1390 GMPR GMPR LMJF_17_1250 LMJF_17_1250 LMJF_17_1370 LMJF_17_1370 LMJF_18_0780 LMJF_18_0780 LMJF_32_0150 LMJF_32_0150 LMJF_31_2370 LMJF_31_2370 LMJF_31_0520 LMJF_31_0520 LMJF_31_0200 LMJF_31_0200 LMJF_30_3250 LMJF_30_3250 LMJF_30_3020 LMJF_30_3020 LMJF_30_1290 LMJF_30_1290 LMJF_30_1150 LMJF_30_1150 LMJF_30_0620 LMJF_30_0620 LMJF_18_0790 LMJF_18_0790 LMJF_30_0480 LMJF_30_0480 LMJF_28_2060 LMJF_28_2060 LMJF_28_1880 LMJF_28_1880 LMJF_28_1740 LMJF_28_1740 LMJF_28_1530 LMJF_28_1530 LMJF_28_1310 LMJF_28_1310 LMJF_28_0810 LMJF_28_0810 LMJF_02_0320 LMJF_02_0320 LMJF_02_0660 LMJF_02_0660 LMJF_25_1315 LMJF_25_1315 LMJF_33_2400 LMJF_33_2400 LMJF_34_0300 LMJF_34_0300 LMJF_34_0740 LMJF_34_0740 LMJF_34_0890 LMJF_34_0890 LMJF_34_1110 LMJF_34_1110 RH RH LMJF_34_2050 LMJF_34_2050 LMJF_34_2750 LMJF_34_2750 LMJF_34_2790 LMJF_34_2790 LMJF_34_3080 LMJF_34_3080 LMJF_34_3980 LMJF_34_3980 LMJF_34_4290 LMJF_34_4290 LMJF_36_0340 LMJF_36_0340 EIF6 EIF6 LMJF_18_0940 LMJF_18_0940
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LMJF_18_1450Uncharacterized protein. (1964 aa)
LMJF_18_1610Uncharacterized protein. (654 aa)
LMJF_19_0100Putative fibrillarin. (297 aa)
LMJF_19_0420DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (151 aa)
LMJF_19_0660Putative DNA-directed RNA polymerase,alpha subunit. (442 aa)
LMJF_19_1210PINc domain-containing protein. (209 aa)
LMJF_20_0420Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (374 aa)
LMJF_20_0650rRNA biogenesis protein-like protein. (738 aa)
LMJF_20_0920Uncharacterized protein. (595 aa)
LMJF_20_1360RNasePH-like protein. (406 aa)
LMJF_20_1670Putative ribosome biogenesis protein. (317 aa)
LMJF_27_0050RNA helicase. (788 aa)
LMJF_27_2250Uncharacterized protein. (246 aa)
LMJF_32_0570Putative RNA helicase. (580 aa)
LMJF_32_0690Ribosomal_S4 domain-containing protein. (226 aa)
LMJF_32_3460Putative exosome-associated protein 2. (312 aa)
LMJF_33_0235Adenosine deaminase-like protein. (601 aa)
LMJF_33_135060S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (181 aa)
LMJF_33_1870Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (652 aa)
LMJF_33_1910WD_REPEATS_REGION domain-containing protein. (584 aa)
LMJF_22_1380Protein MAK16 homolog; Belongs to the MAK16 family. (267 aa)
LMJF_23_0030Putative beta propeller protein. (533 aa)
LMJF_23_0290Checkpoint protein; Belongs to the HUS1 family. (331 aa)
LMJF_24_0250Putative ATP-dependent RNA helicase. (605 aa)
LMJF_24_0540TRM13 domain-containing protein. (462 aa)
LMJF_24_0550TRM13 domain-containing protein. (513 aa)
AIP1Actin-interacting protein 1. (522 aa)
LMJF_25_0140Uncharacterized protein. (129 aa)
LMJF_25_0430Uncharacterized protein. (1017 aa)
LMJF_25_0620DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1616 aa)
PUF8Putative pumillio protein 8. (573 aa)
LMJF_26_0010Brix domain containing-like protein. (362 aa)
LMJF_27_0450Ribosome biogenesis protein. (330 aa)
LMJF_27_1980Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (924 aa)
LMJF_29_0750Putative U3 small nucleolar ribonucleoprotein protein MPP10. (677 aa)
LMJF_29_1400Putative RNA binding protein. (316 aa)
LMJF_35_1090Kri1_C domain-containing protein. (1049 aa)
LMJF_35_1400RRM domain-containing protein. (232 aa)
LMJF_35_1820Uncharacterized protein. (273 aa)
LMJF_35_1990Uncharacterized protein. (1062 aa)
LMJF_35_2480Uncharacterized protein. (339 aa)
LMJF_35_2990Uncharacterized protein. (412 aa)
LMJF_35_3540KH domain-containing protein. (221 aa)
LMJF_21_1230WD_REPEATS_REGION domain-containing protein. (638 aa)
LMJF_35_3880WD_REPEATS_REGION domain-containing protein. (444 aa)
LMJF_35_4030RNA helicase. (690 aa)
LmjF22.0030Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (671 aa)
RPS8A40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (220 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
LMJF_36_6520Uncharacterized protein. (629 aa)
LMJF_28_0720Sas10 domain-containing protein. (560 aa)
LMJF_28_0470WD_REPEATS_REGION domain-containing protein. (796 aa)
LMJF_28_0120Putative DNA-direcetd RNA polymerase II,subunit 9. (140 aa)
LMJF_26_1790Uncharacterized protein. (2766 aa)
LMJF_26_1250Uncharacterized protein. (695 aa)
LMJF_26_0490DNA polymerase sigma-like protein. (479 aa)
L374.02Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (361 aa)
L6586.01Conserved WD40 repeat domain protein. (680 aa)
LMJF_04_0120Putative exosome complex exonuclease RRP40. (300 aa)
L8530.04Uncharacterized protein L8530.04. (873 aa)
P883.41FtsJ-like methyltransferase. (335 aa)
LMJF_36_6400Putative 40S ribosomal protein S8. (260 aa)
LMJF_36_4895Putative exosome-associated protein 4. (221 aa)
LMJF_36_4710WD_REPEATS_REGION domain-containing protein. (727 aa)
LMJF_36_4650Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (227 aa)
LMJF_36_4580Uncharacterized protein. (452 aa)
LMJF_36_4400ATP-dependent RNA helicase-like protein. (964 aa)
LMJF_36_4210Uncharacterized protein. (976 aa)
LMJF_36_3650WD_REPEATS_REGION domain-containing protein. (392 aa)
LMJF_36_3070Fibrillarin. (234 aa)
LMJF_36_3020Putative exosome complex exonuclease rrp41. (246 aa)
LMJF_36_1880Uncharacterized protein. (634 aa)
LMJF_05_0360Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (625 aa)
LMJF_05_0460Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (627 aa)
LMJF_05_0660Nitroreductase-like protein. (323 aa)
LMJF_06_1020G-patch domain-containing protein. (230 aa)
LMJF_07_0470Uncharacterized protein. (807 aa)
LMJF_07_0580CLP1_P domain-containing protein. (1196 aa)
LMJF_07_0700Topoisomerase-related function protein-like protein. (916 aa)
LMJF_09_0005Uncharacterized protein. (373 aa)
LMJF_10_0100SRP40_C domain-containing protein. (257 aa)
LMJF_10_0210Putative nucleolar protein. (473 aa)
LMJF_10_0483Uncharacterized protein. (564 aa)
LMJF_10_0700Uncharacterized protein. (950 aa)
LMJF_10_1030RNA-binding protein-like protein. (379 aa)
LMJF_11_0190Putative DEAD-boc ATP-dependent (RNA) helicase. (609 aa)
LmjF11.0410Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (808 aa)
LMJF_11_0900Putative 60S ribosomal protein L24. (190 aa)
LMJF_12_0570Uncharacterized protein. (1874 aa)
LMJF_12_0590Uncharacterized protein. (1858 aa)
RPL18-A60S ribosomal protein L18. (198 aa)
LMJF_13_1120Putative DNA-directed RNA polymerase ii 8.2 Kdpolypeptide. (89 aa)
LMJF_14_0260VWFA domain-containing protein. (722 aa)
LMJF_14_0410Uncharacterized protein. (1066 aa)
LMJF_14_0570Uncharacterized protein. (1179 aa)
LMJF_14_1240Uncharacterized protein. (302 aa)
LMJF_15_0130Putative ATP-dependent RNA helicase. (648 aa)
LMJF_15_1380Putative nucleolar RNA binding protein. (602 aa)
LMJF_15_1470Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
LMJF_16_0050Uncharacterized protein. (657 aa)
LMJF_16_1350Putative DNA-directed rna polymerase I largest subunit. (1809 aa)
LMJF_16_1390Uncharacterized protein. (287 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily. (492 aa)
LMJF_17_1250RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1061 aa)
LMJF_17_1370Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (865 aa)
LMJF_18_0780Putative DNA-directed RNA polymerases II. (239 aa)
LMJF_32_0150Uncharacterized protein. (999 aa)
LMJF_31_2370WD_REPEATS_REGION domain-containing protein. (521 aa)
LMJF_31_0520CHHC U11-48K-type domain-containing protein. (626 aa)
LMJF_31_0200WD_REPEATS_REGION domain-containing protein. (485 aa)
LMJF_30_3250Putative ATP-dependent RNA helicase. (1025 aa)
LMJF_30_3020KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (321 aa)
LMJF_30_1290Putative U3 small nuclear ribonucleoprotein (SnRNP). (288 aa)
LMJF_30_1150MI domain-containing protein. (858 aa)
LMJF_30_0620Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (245 aa)
LMJF_18_0790Putative DNA-directed RNA polymerase II. (342 aa)
LMJF_30_0480Putative bystin. (469 aa)
LMJF_28_2060DNA-directed RNA polymerase-like protein. (137 aa)
LMJF_28_1880Bms1-type G domain-containing protein. (1261 aa)
LMJF_28_1740SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (587 aa)
LMJF_28_1530Putative ATP dependent DEAD-box helicase; Belongs to the DEAD box helicase family. (389 aa)
LMJF_28_1310Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (900 aa)
LMJF_28_0810DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
LMJF_02_0320Putative ribosomal RNA processing protein. (324 aa)
LMJF_02_0660Uncharacterized protein. (930 aa)
LMJF_25_1315DNA-directed RNA polymerase ii. (84 aa)
LMJF_33_2400Putative ras-like small GTPases. (567 aa)
LMJF_34_0300WD_REPEATS_REGION domain-containing protein. (757 aa)
LMJF_34_0740CBF domain-containing protein. (468 aa)
LMJF_34_0890Putative DNA-directed RNA polymerase subunit. (159 aa)
LMJF_34_1110Shwachman-Bodian-Diamond protein-like protein. (535 aa)
RHPutative ATP dependent DEAD-box helicase. (777 aa)
LMJF_34_2050ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (803 aa)
LMJF_34_2750Methyltransferase-like protein. (427 aa)
LMJF_34_2790Uncharacterized protein. (600 aa)
LMJF_34_3080Putative exosome subunit rrp6p homologue. (742 aa)
LMJF_34_3980Nucleolar protein family a member-like protein. (148 aa)
LMJF_34_4290H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (220 aa)
LMJF_36_0340Putative nuclear protein family a (Nop10p). (63 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (249 aa)
LMJF_18_0940Uncharacterized protein. (1280 aa)
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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