(22 nodes) Antioxidant activity network (Leishmania major)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRYP7	Thiol specific antioxidant. (199 aa)
	LMJF_35_1110	Uncharacterized protein. (329 aa)
	LMJF_36_3010	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (152 aa)
	LMJF_32_2630	Putative superoxide dismutase. (270 aa)
	SODB2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (208 aa)
	SODB1	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (195 aa)
	LMJF_23_0040	Peroxidoxin. (226 aa)
	TDPX-3	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (183 aa)
	LMJF_31_1970	Tryparedoxin-like protein. (180 aa)
	LMJF_31_1960	Tryparedoxin-like protein. (186 aa)
	TDPX-2	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
	TDPX	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (174 aa)
	LMJF_30_1010	Putative ubiquitin conjugation factor E4 B. (1022 aa)
	TRYR	Trypanothione reductase. (491 aa)
	LMJF_30_2770	Putative superoxide dismutase. (268 aa)
	TXN2	Tryparedoxin. (149 aa)
	FESODA	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (230 aa)
	TRYP1	Tryparedoxin peroxidase. (199 aa)
	TXN1	Tryparedoxin. (145 aa)
	LMJF_29_1140	Tryparedoxin-like protein. (275 aa)
	TRYP3	Tryparedoxin peroxidase. (199 aa)
	TRYP4	Tryparedoxin peroxidase. (190 aa)

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FESODA	LMJF_23_0040	Q4QIE0	Q4QBH2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxidoxin.	0.523
FESODA	TDPX	Q4QIE0	Q4Q9B2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.473
FESODA	TDPX-2	Q4QIE0	Q4Q9B3	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.587
FESODA	TDPX-3	Q4QIE0	Q4Q9B4	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.587
FESODA	TRYP1	Q4QIE0	Q4QF80	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Tryparedoxin peroxidase.	0.675
FESODA	TRYP3	Q4QIE0	Q4QF76	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Tryparedoxin peroxidase.	0.675
FESODA	TRYP4	Q4QIE0	Q4QF74	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Tryparedoxin peroxidase.	0.675
FESODA	TRYP7	Q4QIE0	Q4QF68	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Thiol specific antioxidant.	0.677
FESODA	TRYR	Q4QIE0	Q4QJG7	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Trypanothione reductase.	0.407
FESODA	TXN1	Q4QIE0	E9ADX4	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Tryparedoxin.	0.614
FESODA	TXN2	Q4QIE0	E9ADX3	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Tryparedoxin.	0.615
LMJF_23_0040	FESODA	Q4QBH2	Q4QIE0	Peroxidoxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.523
LMJF_23_0040	TRYR	Q4QBH2	Q4QJG7	Peroxidoxin.	Trypanothione reductase.	0.561
LMJF_23_0040	TXN1	Q4QBH2	E9ADX4	Peroxidoxin.	Tryparedoxin.	0.661
LMJF_23_0040	TXN2	Q4QBH2	E9ADX3	Peroxidoxin.	Tryparedoxin.	0.663
LMJF_30_1010	TRYR	Q4Q7K2	Q4QJG7	Putative ubiquitin conjugation factor E4 B.	Trypanothione reductase.	0.425
LMJF_36_3010	TRYP1	Q4Q1B8	Q4QF80	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Tryparedoxin peroxidase.	0.607
LMJF_36_3010	TRYP3	Q4Q1B8	Q4QF76	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Tryparedoxin peroxidase.	0.607
LMJF_36_3010	TRYP4	Q4Q1B8	Q4QF74	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Tryparedoxin peroxidase.	0.607
LMJF_36_3010	TRYP7	Q4Q1B8	Q4QF68	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Thiol specific antioxidant.	0.508