14 items (Leishmania major) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LMJF_36_4650	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (227 aa)
	LMJF_27_0450	Ribosome biogenesis protein. (330 aa)
	LMJF_27_1980	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (924 aa)
	LMJF_35_1820	Uncharacterized protein. (273 aa)
	LmjF22.0030	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (671 aa)
	LMJF_36_6400	Putative 40S ribosomal protein S8. (260 aa)
	LMJF_33_1350	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (181 aa)
	LMJF_31_0200	WD_REPEATS_REGION domain-containing protein. (485 aa)
	LMJF_30_0620	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (245 aa)
	LMJF_22_1380	Protein MAK16 homolog; Belongs to the MAK16 family. (267 aa)
	LMJF_18_1610	Uncharacterized protein. (654 aa)
	LMJF_16_0890	Uncharacterized protein. (662 aa)
	LmjF11.0410	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (808 aa)
	P883.41	FtsJ-like methyltransferase. (335 aa)

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LMJF_16_0890	LMJF_18_1610	Q4QET0	Q4QDM8	Uncharacterized protein.	Uncharacterized protein.	0.953
LMJF_16_0890	LMJF_22_1380	Q4QET0	Q4QBK9	Uncharacterized protein.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.999
LMJF_16_0890	LMJF_27_0450	Q4QET0	E9AD22	Uncharacterized protein.	Ribosome biogenesis protein.	0.998
LMJF_16_0890	LMJF_27_1980	Q4QET0	E9ADH8	Uncharacterized protein.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.931
LMJF_16_0890	LMJF_30_0620	Q4QET0	Q4Q7P4	Uncharacterized protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.928
LMJF_16_0890	LMJF_31_0200	Q4QET0	Q4Q6P4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.976
LMJF_16_0890	LMJF_33_1350	Q4QET0	Q4Q453	Uncharacterized protein.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.975
LMJF_16_0890	LMJF_35_1820	Q4QET0	E9AF03	Uncharacterized protein.	Uncharacterized protein.	0.994
LMJF_16_0890	LMJF_36_4650	Q4QET0	Q4Q0U9	Uncharacterized protein.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.990
LMJF_16_0890	LMJF_36_6400	Q4QET0	Q4Q0B8	Uncharacterized protein.	Putative 40S ribosomal protein S8.	0.983
LMJF_16_0890	LmjF11.0410	Q4QET0	Q4QH39	Uncharacterized protein.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.996
LMJF_16_0890	LmjF22.0030	Q4QET0	O97209	Uncharacterized protein.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.995
LMJF_16_0890	P883.41	Q4QET0	Q9BHC8	Uncharacterized protein.	FtsJ-like methyltransferase.	0.931
LMJF_18_1610	LMJF_16_0890	Q4QDM8	Q4QET0	Uncharacterized protein.	Uncharacterized protein.	0.953
LMJF_18_1610	LMJF_22_1380	Q4QDM8	Q4QBK9	Uncharacterized protein.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.980
LMJF_18_1610	LMJF_27_0450	Q4QDM8	E9AD22	Uncharacterized protein.	Ribosome biogenesis protein.	0.992
LMJF_18_1610	LMJF_27_1980	Q4QDM8	E9ADH8	Uncharacterized protein.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.975
LMJF_18_1610	LMJF_30_0620	Q4QDM8	Q4Q7P4	Uncharacterized protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.951
LMJF_18_1610	LMJF_31_0200	Q4QDM8	Q4Q6P4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.991
LMJF_18_1610	LMJF_33_1350	Q4QDM8	Q4Q453	Uncharacterized protein.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.991