55 items (Leishmania major) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LMJF_36_4210	Uncharacterized protein. (976 aa)
	LMJF_36_4400	ATP-dependent RNA helicase-like protein. (964 aa)
	LMJF_36_4580	Uncharacterized protein. (452 aa)
	UB-EP52	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
	LmjF22.0030	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (671 aa)
	LMJF_29_1400	Putative RNA binding protein. (316 aa)
	LMJF_29_0750	Putative U3 small nucleolar ribonucleoprotein protein MPP10. (677 aa)
	LMJF_25_1315	DNA-directed RNA polymerase ii. (84 aa)
	LMJF_35_4030	RNA helicase. (690 aa)
	LMJF_35_1990	Uncharacterized protein. (1062 aa)
	L8530.04	Uncharacterized protein L8530.04. (873 aa)
	LMJF_08_0410	WD_REPEATS_REGION domain-containing protein. (1407 aa)
	LMJF_10_0210	Putative nucleolar protein. (473 aa)
	LMJF_10_1030	RNA-binding protein-like protein. (379 aa)
	LmjF11.0410	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (808 aa)
	LMJF_13_1120	Putative DNA-directed RNA polymerase ii 8.2 Kdpolypeptide. (89 aa)
	LMJF_14_0410	Uncharacterized protein. (1066 aa)
	LMJF_14_0570	Uncharacterized protein. (1179 aa)
	LMJF_15_1380	Putative nucleolar RNA binding protein. (602 aa)
	LMJF_15_1470	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
	LMJF_16_0050	Uncharacterized protein. (657 aa)
	LMJF_16_1340	Uncharacterized protein. (3758 aa)
	LMJF_16_1350	Putative DNA-directed rna polymerase I largest subunit. (1809 aa)
	LMJF_18_0780	Putative DNA-directed RNA polymerases II. (239 aa)
	LMJF_18_0790	Putative DNA-directed RNA polymerase II. (342 aa)
	LMJF_18_0830	Periodic tryptophan protein 2-like protein. (942 aa)
	LMJF_18_0940	Uncharacterized protein. (1280 aa)
	LMJF_19_0100	Putative fibrillarin. (297 aa)
	LMJF_19_0660	Putative DNA-directed RNA polymerase,alpha subunit. (442 aa)
	LMJF_20_0920	Uncharacterized protein. (595 aa)
	LMJF_21_1760	Putative centromere/microtubule binding protein cbf5. (430 aa)
	LMJF_22_1380	Protein MAK16 homolog; Belongs to the MAK16 family. (267 aa)
	LMJF_23_1065	Uncharacterized protein. (484 aa)
	LMJF_24_0620	Ubiquitin carboxyl-terminal hydrolase. (809 aa)
	LMJF_24_1490	WD_REPEATS_REGION domain-containing protein. (434 aa)
	LMJF_25_0140	Uncharacterized protein. (129 aa)
	LMJF_25_0620	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1616 aa)
	LMJF_25_1210	Uncharacterized protein. (1063 aa)
	LMJF_26_1790	Uncharacterized protein. (2766 aa)
	LMJF_28_0810	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	LMJF_28_1740	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (587 aa)
	LMJF_28_2060	DNA-directed RNA polymerase-like protein. (137 aa)
	LMJF_30_0620	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (245 aa)
	LMJF_30_1290	Putative U3 small nuclear ribonucleoprotein (SnRNP). (288 aa)
	LMJF_32_0690	Ribosomal_S4 domain-containing protein. (226 aa)
	LMJF_32_2810	Putative RNA-binding protein. (447 aa)
	LMJF_32_3570	Uncharacterized protein. (1229 aa)
	LMJF_33_0580	Nkap_C domain-containing protein. (380 aa)
	LMJF_34_0890	Putative DNA-directed RNA polymerase subunit. (159 aa)
	LMJF_34_1155	Uncharacterized protein. (204 aa)
	LMJF_34_3980	Nucleolar protein family a member-like protein. (148 aa)
	LMJF_34_4290	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (220 aa)
	LMJF_36_0340	Putative nuclear protein family a (Nop10p). (63 aa)
	LMJF_36_3070	Fibrillarin. (234 aa)
	LMJF_36_4145	Transcription factor S-II-like protein. (254 aa)

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L8530.04	LMJF_08_0410	Q9GRN2	Q4QIC8	Uncharacterized protein L8530.04.	WD_REPEATS_REGION domain-containing protein.	0.658
L8530.04	LMJF_10_0210	Q9GRN2	Q4QHJ7	Uncharacterized protein L8530.04.	Putative nucleolar protein.	0.939
L8530.04	LMJF_10_1030	Q9GRN2	Q4QHB1	Uncharacterized protein L8530.04.	RNA-binding protein-like protein.	0.669
L8530.04	LMJF_14_0410	Q9GRN2	Q4QFU3	Uncharacterized protein L8530.04.	Uncharacterized protein.	0.571
L8530.04	LMJF_15_1380	Q9GRN2	Q4QF42	Uncharacterized protein L8530.04.	Putative nucleolar RNA binding protein.	0.943
L8530.04	LMJF_15_1470	Q9GRN2	Q4QF32	Uncharacterized protein L8530.04.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.842
L8530.04	LMJF_16_0050	Q9GRN2	Q4QF15	Uncharacterized protein L8530.04.	Uncharacterized protein.	0.410
L8530.04	LMJF_16_1350	Q9GRN2	Q4QEN2	Uncharacterized protein L8530.04.	Putative DNA-directed rna polymerase I largest subunit.	0.769
L8530.04	LMJF_18_0830	Q9GRN2	Q4QDV9	Uncharacterized protein L8530.04.	Periodic tryptophan protein 2-like protein.	0.987
L8530.04	LMJF_18_0940	Q9GRN2	Q4QDU8	Uncharacterized protein L8530.04.	Uncharacterized protein.	0.974
L8530.04	LMJF_19_0100	Q9GRN2	Q4QDL1	Uncharacterized protein L8530.04.	Putative fibrillarin.	0.849
L8530.04	LMJF_19_0660	Q9GRN2	Q4QDF5	Uncharacterized protein L8530.04.	Putative DNA-directed RNA polymerase,alpha subunit.	0.553
L8530.04	LMJF_20_0920	Q9GRN2	Q4QCV4	Uncharacterized protein L8530.04.	Uncharacterized protein.	0.941
L8530.04	LMJF_22_1380	Q9GRN2	Q4QBK9	Uncharacterized protein L8530.04.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.669
L8530.04	LMJF_24_1490	Q9GRN2	Q4QAI2	Uncharacterized protein L8530.04.	WD_REPEATS_REGION domain-containing protein.	0.658
L8530.04	LMJF_25_0620	Q9GRN2	Q4QA33	Uncharacterized protein L8530.04.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.768
L8530.04	LMJF_26_1790	Q9GRN2	Q4Q913	Uncharacterized protein L8530.04.	Uncharacterized protein.	0.979
L8530.04	LMJF_28_2060	Q9GRN2	Q4Q860	Uncharacterized protein L8530.04.	DNA-directed RNA polymerase-like protein.	0.408
L8530.04	LMJF_29_0750	Q9GRN2	E9ADS7	Uncharacterized protein L8530.04.	Putative U3 small nucleolar ribonucleoprotein protein MPP10.	0.938
L8530.04	LMJF_30_0620	Q9GRN2	Q4Q7P4	Uncharacterized protein L8530.04.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.566