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LMJF_33_2600 LMJF_33_2600 LMJF_25_2130 LMJF_25_2130 LMJF_25_1020 LMJF_25_1020 LMJF_24_2030 LMJF_24_2030 LMJF_24_1820 LMJF_24_1820 LMJF_24_1810 LMJF_24_1810 LMJF_24_1640 LMJF_24_1640 LMJF_24_0770 LMJF_24_0770 LMJF_23_0860 LMJF_23_0860 LMJF_23_1600 LMJF_23_1600 LMJF_23_1590 LMJF_23_1590 LMJF_23_0360 LMJF_23_0360 gMDH gMDH LMJF_18_0080 LMJF_18_0080 GDH GDH INO1 INO1 LMJF_14_1280 LMJF_14_1280 LMJF_14_0290 LMJF_14_0290 P5CR P5CR LMJF_13_1350 LMJF_13_1350 LMJF_13_0720 LMJF_13_0720 LMJF_12_0390 LMJF_12_0390 LMJF_10_0570 LMJF_10_0570 LMJF_10_0560 LMJF_10_0560 LMJF_02_0730 LMJF_02_0730 LMJF_03_0030 LMJF_03_0030 GPD GPD LMJF_26_0320 LMJF_26_0320 LMJF_26_1550 LMJF_26_1550 LMJF_26_2230 LMJF_26_2230 LMJF_28_0380 LMJF_28_0380 LMJF_28_0940 LMJF_28_0940 cMDH cMDH LMJF_28_2910 LMJF_28_2910 LMJF_30_0180 LMJF_30_0180 LMJF_30_2970 LMJF_30_2970 LMJF_30_2980 LMJF_30_2980 LMJF_10_0090 LMJF_10_0090 LMJF_07_0260 LMJF_07_0260 LMJF_06_0350 LMJF_06_0350 LMJF_05_0520 LMJF_05_0520 gnd gnd L7836.05 L7836.05 LMJF_04_0290 LMJF_04_0290 LMJF_33_0520 LMJF_33_0520 LMJF_33_1590 LMJF_33_1590 LMJF_33_2300 LMJF_33_2300 LMJF_34_0010 LMJF_34_0010 G6PD G6PD LMJF_34_0130 LMJF_34_0130 LMJF_34_0140 LMJF_34_0140 LMJF_34_0150 LMJF_34_0150 mMDH mMDH LMJF_34_0760 LMJF_34_0760 LMJF_34_1400 LMJF_34_1400 LMJF_34_1410 LMJF_34_1410 LMJF_34_3190 LMJF_34_3190 QDPR-1 QDPR-1 QDPR-7 QDPR-7 LMJF_03_0570 LMJF_03_0570 KAR1 KAR1 LMJF_27_2650 LMJF_27_2650 LMJF_27_1950 LMJF_27_1950 LMJF_29_1010 LMJF_29_1010 LMJF_36_1140 LMJF_36_1140 LMJF_36_2340 LMJF_36_2340 LMJF_36_3410 LMJF_36_3410 LMJF_36_3910 LMJF_36_3910 LMJF_36_4170 LMJF_36_4170 PTR1 PTR1 LMJF_35_4750 LMJF_35_4750 LMJF_35_2170 LMJF_35_2170 LMJF_35_2150 LMJF_35_2150 LMJF_35_2020 LMJF_35_2020 LMJF_35_1230 LMJF_35_1230 LMJF_35_1220 LMJF_35_1220 LMJF_35_0330 LMJF_35_0330 LMJF_29_2080 LMJF_29_2080
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LMJF_33_2600Putative enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase. (934 aa)
LMJF_25_2130Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (299 aa)
LMJF_25_1020Dehydrogenase-like protein. (431 aa)
LMJF_24_2030Putative 3-oxoacyl-(Acyl-carrier protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
LMJF_24_1820Putative short chain dehydrogenase/reductase. (507 aa)
LMJF_24_1810Putative short chain dehydrogenase/reductase. (440 aa)
LMJF_24_1640Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (579 aa)
LMJF_24_0770Putative malic enzyme. (573 aa)
LMJF_23_0860Quinone oxidoreductase-like protein. (340 aa)
LMJF_23_1600Oxidoreductase-like protein. (369 aa)
LMJF_23_1590Oxidoreductase-like protein. (465 aa)
LMJF_23_0360Putative NADP-dependent alcohol dehydrogenase. (352 aa)
gMDHGlycosomal malate dehydrogenase; Belongs to the LDH/MDH superfamily. (322 aa)
LMJF_18_00803Beta_HSD domain-containing protein. (479 aa)
GDHNAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1020 aa)
INO1Inositol-3-phosphate synthase. (526 aa)
LMJF_14_1280F420_oxidored domain-containing protein. (578 aa)
LMJF_14_0290Uncharacterized protein. (280 aa)
P5CRPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (272 aa)
LMJF_13_1350Uncharacterized protein. (1146 aa)
LMJF_13_0720Oxidoreductase-like protein. (392 aa)
LMJF_12_0390Uncharacterized protein. (416 aa)
LMJF_10_0570Zinc-binding dehydrogenase-like protein. (478 aa)
LMJF_10_0560Zinc binding dehydrogenase-like protein. (371 aa)
LMJF_02_0730Dehydrogenase/oxidoreductase-like protein. (128 aa)
LMJF_03_0030D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (511 aa)
GPDGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal. (367 aa)
LMJF_26_0320Putative C-1-tetrahydrofolate synthase,cytoplasmic. (298 aa)
LMJF_26_1550Trifunctional enzyme alpha subunit, mitochondrial-like protein. (726 aa)
LMJF_26_2230Putative GDP-mannose 4,6 dehydratase. (446 aa)
LMJF_28_0380Sacchrp_dh_NADP domain-containing protein. (392 aa)
LMJF_28_0940Oxidoreductase-like protein. (973 aa)
cMDHMalate dehydrogenase. (324 aa)
LMJF_28_2910Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (452 aa)
LMJF_30_0180Putative 2-hydroxy-3-oxopropionate reductase. (299 aa)
LMJF_30_2970Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
LMJF_30_2980Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
LMJF_10_0090Dehydrogenase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (412 aa)
LMJF_07_0260Homoserine dehydrogenase. (366 aa)
LMJF_06_0350NAD(P)-dependent steroid dehydrogenase-like protein; Belongs to the 3-beta-HSD family. (378 aa)
LMJF_05_0520Nuclear receptor binding factor-like protein. (340 aa)
gnd6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (479 aa)
L7836.05Oxidoreductase-like protein. (374 aa)
LMJF_04_0290ADH_N domain-containing protein. (447 aa)
LMJF_33_0520Putative d-xylulose reductase. (349 aa)
LMJF_33_1590Uncharacterized protein. (326 aa)
LMJF_33_2300UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (391 aa)
LMJF_34_0010Uncharacterized protein. (306 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (562 aa)
LMJF_34_0130Malate dehydrogenase. (342 aa)
LMJF_34_0140Malate dehydrogenase. (317 aa)
LMJF_34_0150Putative malate dehydrogenase; Belongs to the LDH/MDH superfamily. (331 aa)
mMDHMalate dehydrogenase. (325 aa)
LMJF_34_0760Uncharacterized protein. (470 aa)
LMJF_34_1400D-isomer specific 2-hydroxyacid dehydrogenase-protein. (326 aa)
LMJF_34_1410D-isomer specific 2-hydroxyacid dehydrogenase-like protein. (335 aa)
LMJF_34_3190Epimerase domain-containing protein. (510 aa)
QDPR-1Quinonoid dihydropteridine reductase. (229 aa)
QDPR-7Quinonoid dihydropteridine reductase. (229 aa)
LMJF_03_0570Putative quinone oxidoreductase. (332 aa)
KAR1Putative 3-oxoacyl-ACP reductase. (293 aa)
LMJF_27_2650Dehydrogenase/oxidoreductase-like protein. (128 aa)
LMJF_27_1950Uncharacterized protein. (1513 aa)
LMJF_29_1010PKS_ER domain-containing protein. (350 aa)
LMJF_36_1140Putative short chain 3-hydroxyacyl-CoA dehydrogenase. (305 aa)
LMJF_36_2340Uncharacterized protein. (409 aa)
LMJF_36_3410Short chain dehydrogenase-like protein. (376 aa)
LMJF_36_3910Adenosylhomocysteinase. (437 aa)
LMJF_36_4170Putative oxidoreductase. (340 aa)
PTR1Pteridine reductase 1; Exhibits a NADPH-dependent biopterin reductase activity. Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin. Confers resistance to methotrexate (MTX); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (288 aa)
LMJF_35_4750Glyceraldehyde-3-phosphate dehydrogenase-like protein. (349 aa)
LMJF_35_2170Uncharacterized protein. (484 aa)
LMJF_35_2150Uncharacterized protein. (440 aa)
LMJF_35_2020Uncharacterized protein. (369 aa)
LMJF_35_1230Putative short chain dehydrogenase. (254 aa)
LMJF_35_1220Putative short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (233 aa)
LMJF_35_03303-keto-dihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa)
LMJF_29_2080Uncharacterized protein. (451 aa)
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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