(66 nodes) Mixed, incl. Clathrin binding, and trans-Golgi Network Vesicle Budding network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2SP22	PX domain-containing protein. (947 aa)
	A0A2L2SQE8	Rad60-SLD_2 domain-containing protein. (262 aa)
	A0A2L2SSH4	Uncharacterized protein. (397 aa)
	A0A2L2SU18	Uncharacterized protein. (1465 aa)
	A0A2L2SU59	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (448 aa)
	A0A2L2SWK7	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (713 aa)
	A0A2L2SWZ3	Uncharacterized protein. (1054 aa)
	A0A2L2SXV5	PX domain-containing protein. (459 aa)
	A0A2L2SY81	Uncharacterized protein. (692 aa)
	A0A2L2T131	CFEM domain-containing protein. (154 aa)
	A0A2L2T1Q7	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (987 aa)
	A0A2L2T2R6	Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (610 aa)
	A0A2L2T3P0	Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (202 aa)
	A0A2L2T3X4	ENTH domain-containing protein. (622 aa)
	A0A2L2T510	PX domain-containing protein. (558 aa)
	A0A2L2T746	PX domain-containing protein. (739 aa)
	A0A2L2T909	EH domain-containing protein. (614 aa)
	A0A2L2T970	Uncharacterized protein. (269 aa)
	A0A2L2TA33	CFEM domain-containing protein. (95 aa)
	A0A2L2TA91	Clat_adaptor_s domain-containing protein. (219 aa)
	A0A2L2TA96	GED domain-containing protein. (400 aa)
	A0A2L2TAS3	Uncharacterized protein. (316 aa)
	A0A2L2TBU0	Zn(2)-C6 fungal-type domain-containing protein. (652 aa)
	A0A2L2TBX1	PX domain-containing protein. (617 aa)
	A0A2L2TBX7	Protein kinase domain-containing protein. (1017 aa)
	A0A2L2TC17	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	A0A2L2TCM9	CFEM domain-containing protein. (206 aa)
	A0A2L2TCR9	Cupin_2 domain-containing protein. (325 aa)
	A0A2L2TD71	Rab-GAP TBC domain-containing protein. (1120 aa)
	A0A2L2TE86	Uncharacterized protein. (476 aa)
	A0A2L2TEL8	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (208 aa)
	A0A2L2TEP1	Uncharacterized protein. (715 aa)
	A0A2L2TES3	UBA domain-containing protein. (908 aa)
	A0A2L2TF11	GH16 domain-containing protein. (374 aa)
	A0A2L2TF25	Cupin_2 domain-containing protein. (347 aa)
	A0A2L2TF31	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (732 aa)
	A0A2L2TFK8	Uncharacterized protein. (479 aa)
	A0A2L2TFN2	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (782 aa)
	A0A2L2TFS2	Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1511 aa)
	A0A2L2TGC1	ENTH domain-containing protein. (549 aa)
	A0A2L2TGH7	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (852 aa)
	A0A2L2TGW6	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1085 aa)
	A0A2L2TIG4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (747 aa)
	A0A2L2TJX1	AP-1 complex subunit gamma. (826 aa)
	A0A2L2TK52	ENTH domain-containing protein. (580 aa)
	A0A2L2TKC5	Uncharacterized protein. (318 aa)
	A0A2L2TM80	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (902 aa)
	A0A2L2TMJ9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (189 aa)
	A0A2L2TMR5	CFEM domain-containing protein. (190 aa)
	A0A2L2TNT6	SAC domain-containing protein. (1308 aa)
	A0A2L2TP53	PX domain-containing protein. (163 aa)
	A0A2L2TRT4	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (955 aa)
	A0A2L2TS67	Uncharacterized protein. (1247 aa)
	A0A2L2TSA5	Glycosidase; Belongs to the glycosyl hydrolase 16 family. (474 aa)
	A0A2L2TSH2	Uncharacterized protein. (462 aa)
	A0A2L2TSN1	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (539 aa)
	A0A2L2TT67	Uncharacterized protein. (1227 aa)
	A0A2L2TUU6	Uncharacterized protein. (922 aa)
	A0A2L2TVB0	Uncharacterized protein. (269 aa)
	A0A2L2TVY7	DUF1681 domain-containing protein. (254 aa)
	A0A2L2TWC6	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (584 aa)
	A0A2L2TWD8	BAR domain-containing protein. (403 aa)
	A0A2L2TY09	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (238 aa)
	A0A2L2TYB8	Uncharacterized protein. (950 aa)
	A0A2L2U200	MHD domain-containing protein. (886 aa)
	A0A2L2U384	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SP22	A0A2L2SQE8	PX domain-containing protein.	Rad60-SLD_2 domain-containing protein.	0.474
A0A2L2SP22	A0A2L2SWK7	PX domain-containing protein.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.474
A0A2L2SP22	A0A2L2SWZ3	PX domain-containing protein.	Uncharacterized protein.	0.574
A0A2L2SP22	A0A2L2SY81	PX domain-containing protein.	Uncharacterized protein.	0.521
A0A2L2SP22	A0A2L2T131	PX domain-containing protein.	CFEM domain-containing protein.	0.489
A0A2L2SP22	A0A2L2T3P0	PX domain-containing protein.	Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family.	0.637
A0A2L2SP22	A0A2L2T510	PX domain-containing protein.	PX domain-containing protein.	0.452
A0A2L2SP22	A0A2L2TA33	PX domain-containing protein.	CFEM domain-containing protein.	0.489
A0A2L2SP22	A0A2L2TA91	PX domain-containing protein.	Clat_adaptor_s domain-containing protein.	0.552
A0A2L2SP22	A0A2L2TA96	PX domain-containing protein.	GED domain-containing protein.	0.509
A0A2L2SP22	A0A2L2TAS3	PX domain-containing protein.	Uncharacterized protein.	0.636
A0A2L2SP22	A0A2L2TC17	PX domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.624
A0A2L2SP22	A0A2L2TCM9	PX domain-containing protein.	CFEM domain-containing protein.	0.489
A0A2L2SP22	A0A2L2TEP1	PX domain-containing protein.	Uncharacterized protein.	0.495
A0A2L2SP22	A0A2L2TES3	PX domain-containing protein.	UBA domain-containing protein.	0.520
A0A2L2SP22	A0A2L2TF31	PX domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.509
A0A2L2SP22	A0A2L2TFN2	PX domain-containing protein.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.489
A0A2L2SP22	A0A2L2TFS2	PX domain-containing protein.	Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.	0.610
A0A2L2SP22	A0A2L2TGH7	PX domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.509
A0A2L2SP22	A0A2L2TGW6	PX domain-containing protein.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.509