(78 nodes) Sulfur compound biosynthetic process network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A2L2TG22	Uncharacterized protein. (176 aa)
	A0A2L2U578	Zn(2)-C6 fungal-type domain-containing protein. (563 aa)
	A0A2L2U2X5	Uncharacterized protein. (426 aa)
	A0A2L2U2L4	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (409 aa)
	A0A2L2TZ29	Flavodoxin-like domain-containing protein. (1535 aa)
	A0A2L2TZ17	Aminotran_5 domain-containing protein. (454 aa)
	A0A2L2TY41	Uncharacterized protein. (446 aa)
	A0A2L2TXL7	NMT1 domain-containing protein. (345 aa)
	ADI1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (220 aa)
	A0A2L2TUV8	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (402 aa)
	A0A2L2TS01	AB hydrolase-1 domain-containing protein. (504 aa)
	A0A2L2TRT1	Uncharacterized protein. (277 aa)
	A0A2L2TQX6	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family. (311 aa)
	A0A2L2TQU1	Uncharacterized protein. (468 aa)
	A0A2L2TQG9	PALP domain-containing protein. (311 aa)
	A0A2L2TQ15	Acetyl-coenzyme A synthetase. (662 aa)
	A0A2L2TPS3	Uncharacterized protein. (717 aa)
	A0A2L2TNY0	Probable acetate kinase. (415 aa)
	A0A2L2TNW4	Uncharacterized protein. (476 aa)
	A0A2L2TNN1	Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (322 aa)
	A0A2L2TNK8	Uncharacterized protein. (356 aa)
	A0A2L2TNF6	Uncharacterized protein. (272 aa)
	A0A2L2TMK1	Rhodanese domain-containing protein. (541 aa)
	A0A2L2TLB6	Acetyl-coenzyme A synthetase. (719 aa)
	A0A2L2TKX4	ACPS domain-containing protein. (292 aa)
	A0A2L2TK59	Semialdhyde_dh domain-containing protein. (364 aa)
	A0A2L2TJ52	Uncharacterized protein. (713 aa)
	A0A2L2THM8	Uncharacterized protein. (410 aa)
	A0A2L2TGS9	PALP domain-containing protein. (445 aa)
	A0A2L2TGL6	Uncharacterized protein. (766 aa)
	MDE1	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (256 aa)
	A0A2L2TEY7	Uncharacterized protein. (489 aa)
	A0A2L2TDU9	Uncharacterized protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (450 aa)
	A0A2L2TCV6	Glutathione synthetase. (516 aa)
	A0A2L2TCR8	Uncharacterized protein. (423 aa)
	A0A2L2TCG4	FAD-binding FR-type domain-containing protein. (616 aa)
	A0A2L2TC45	Uncharacterized protein. (863 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (388 aa)
	A0A2L2TBN3	Pyr_redox_2 domain-containing protein. (446 aa)
	A0A2L2TBD8	Uncharacterized protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (434 aa)
	A0A2L2TAX0	Uncharacterized protein. (702 aa)
	A0A2L2TAM9	Aldo_ket_red domain-containing protein. (312 aa)
	A0A2L2TAK9	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (517 aa)
	A0A2L2TA12	Uncharacterized protein. (568 aa)
	A0A2L2T8H6	Uncharacterized protein. (549 aa)
	A0A2L2T7U2	CsbD domain-containing protein. (181 aa)
	A0A2L2T6D5	Rhodanese domain-containing protein. (534 aa)
	A0A2L2T627	Hcy-binding domain-containing protein. (341 aa)
	A0A2L2T616	Uncharacterized protein. (944 aa)
	A0A2L2T5W0	Homoserine dehydrogenase. (365 aa)
	A0A2L2T5M0	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (672 aa)
	A0A2L2T5K3	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (207 aa)
	A0A2L2T581	UDPG_MGDP_dh_C domain-containing protein. (604 aa)
	A0A2L2T4E1	Uncharacterized protein. (604 aa)
	A0A2L2T418	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (132 aa)
	A0A2L2T2T9	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (617 aa)
	A0A2L2T2P3	Uncharacterized protein. (423 aa)
	A0A2L2T2I2	Zn(2)-C6 fungal-type domain-containing protein. (632 aa)
	A0A2L2T0C6	Uncharacterized protein. (149 aa)
	A0A2L2T020	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (456 aa)
	A0A2L2SZZ5	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (307 aa)
	A0A2L2SZY5	Uncharacterized protein. (510 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (574 aa)
	A0A2L2SUY3	Methyltransf_33 domain-containing protein. (326 aa)
	A0A2L2SUQ4	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (386 aa)
	A0A2L2SU90	Uncharacterized protein. (776 aa)
	A0A2L2STP9	PAPS_reduct domain-containing protein. (316 aa)
	A0A2L2STP5	RmlD_sub_bind domain-containing protein. (319 aa)
	A0A2L2STJ2	Methyltransf_33 domain-containing protein. (358 aa)
	A0A2L2ST70	Meth_synt_2 domain-containing protein. (397 aa)
	A0A2L2SSG4	PALP domain-containing protein. (313 aa)
	A0A2L2SSD3	Uncharacterized protein. (421 aa)
	A0A2L2SS03	Meth_synt_2 domain-containing protein. (404 aa)
	A0A2L2SR17	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (410 aa)
	A0A2L2SPR9	Uncharacterized protein. (2280 aa)
	A0A2L2SPE7	Fungal_trans domain-containing protein. (568 aa)
	A0A2L2SNY4	PALP domain-containing protein. (371 aa)
	A0A2L2SMM8	Pyr_redox_2 domain-containing protein. (316 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2L2SMM8	A0A2L2SPR9	A0A2L2SMM8	A0A2L2SPR9	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.618
A0A2L2SMM8	A0A2L2SSD3	A0A2L2SMM8	A0A2L2SSD3	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.607
A0A2L2SMM8	A0A2L2T020	A0A2L2SMM8	A0A2L2T020	Pyr_redox_2 domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.628
A0A2L2SMM8	A0A2L2TAX0	A0A2L2SMM8	A0A2L2TAX0	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.536
A0A2L2SMM8	A0A2L2TCR8	A0A2L2SMM8	A0A2L2TCR8	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.628
A0A2L2SMM8	A0A2L2TLB6	A0A2L2SMM8	A0A2L2TLB6	Pyr_redox_2 domain-containing protein.	Acetyl-coenzyme A synthetase.	0.536
A0A2L2SMM8	A0A2L2TQ15	A0A2L2SMM8	A0A2L2TQ15	Pyr_redox_2 domain-containing protein.	Acetyl-coenzyme A synthetase.	0.536
A0A2L2SMM8	A0A2L2TS01	A0A2L2SMM8	A0A2L2TS01	Pyr_redox_2 domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.422
A0A2L2SMM8	A0A2L2U2X5	A0A2L2SMM8	A0A2L2U2X5	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.607
A0A2L2SNY4	A0A2L2SPE7	A0A2L2SNY4	A0A2L2SPE7	PALP domain-containing protein.	Fungal_trans domain-containing protein.	0.480
A0A2L2SNY4	A0A2L2SPR9	A0A2L2SNY4	A0A2L2SPR9	PALP domain-containing protein.	Uncharacterized protein.	0.684
A0A2L2SNY4	A0A2L2SS03	A0A2L2SNY4	A0A2L2SS03	PALP domain-containing protein.	Meth_synt_2 domain-containing protein.	0.768
A0A2L2SNY4	A0A2L2SSG4	A0A2L2SNY4	A0A2L2SSG4	PALP domain-containing protein.	PALP domain-containing protein.	0.541
A0A2L2SNY4	A0A2L2ST70	A0A2L2SNY4	A0A2L2ST70	PALP domain-containing protein.	Meth_synt_2 domain-containing protein.	0.568
A0A2L2SNY4	A0A2L2STP9	A0A2L2SNY4	A0A2L2STP9	PALP domain-containing protein.	PAPS_reduct domain-containing protein.	0.460
A0A2L2SNY4	A0A2L2T2P3	A0A2L2SNY4	A0A2L2T2P3	PALP domain-containing protein.	Uncharacterized protein.	0.970
A0A2L2SNY4	A0A2L2T2T9	A0A2L2SNY4	A0A2L2T2T9	PALP domain-containing protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.558
A0A2L2SNY4	A0A2L2T4E1	A0A2L2SNY4	A0A2L2T4E1	PALP domain-containing protein.	Uncharacterized protein.	0.959
A0A2L2SNY4	A0A2L2T5K3	A0A2L2SNY4	A0A2L2T5K3	PALP domain-containing protein.	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.	0.593
A0A2L2SNY4	A0A2L2T5M0	A0A2L2SNY4	A0A2L2T5M0	PALP domain-containing protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.558