(15 nodes) Mitotic DNA integrity checkpoint signaling network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2TSC0	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (464 aa)
	A0A2L2TVE3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (719 aa)
	A0A2L2TXF0	HORMA domain-containing protein. (231 aa)
	A0A2L2TXW3	MRC1 domain-containing protein. (1290 aa)
	A0A2L2U1I8	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	A0A2L2T426	Protein kinase domain-containing protein. (494 aa)
	A0A2L2STJ5	FHA domain-containing protein. (846 aa)
	A0A2L2TSB0	Uncharacterized protein. (849 aa)
	A0A2L2TLL3	Uncharacterized protein. (1195 aa)
	A0A2L2TH12	Uncharacterized protein. (860 aa)
	A0A2L2TG87	Checkpoint protein; Belongs to the HUS1 family. (343 aa)
	A0A2L2TFR0	Uncharacterized protein. (346 aa)
	A0A2L2TBF4	Protein kinase domain-containing protein. (510 aa)
	A0A2L2TA17	Cell division control protein; Belongs to the CDC6/cdc18 family. (609 aa)
	A0A2L2T708	ERCC4 domain-containing protein. (676 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2STJ5	A0A2L2TBF4	FHA domain-containing protein.	Protein kinase domain-containing protein.	0.737
A0A2L2STJ5	A0A2L2TG87	FHA domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.781
A0A2L2STJ5	A0A2L2TH12	FHA domain-containing protein.	Uncharacterized protein.	0.836
A0A2L2STJ5	A0A2L2TLL3	FHA domain-containing protein.	Uncharacterized protein.	0.735
A0A2L2STJ5	A0A2L2TSB0	FHA domain-containing protein.	Uncharacterized protein.	0.881
A0A2L2STJ5	A0A2L2TSC0	FHA domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.784
A0A2L2STJ5	A0A2L2TVE3	FHA domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
A0A2L2STJ5	A0A2L2U1I8	FHA domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.513
A0A2L2T426	A0A2L2TA17	Protein kinase domain-containing protein.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.872
A0A2L2T426	A0A2L2TBF4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.867
A0A2L2T426	A0A2L2TH12	Protein kinase domain-containing protein.	Uncharacterized protein.	0.500
A0A2L2T426	A0A2L2TLL3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.985
A0A2L2T426	A0A2L2TSB0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.665
A0A2L2T426	A0A2L2TSC0	Protein kinase domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.484
A0A2L2T426	A0A2L2TXF0	Protein kinase domain-containing protein.	HORMA domain-containing protein.	0.539
A0A2L2T426	A0A2L2TXW3	Protein kinase domain-containing protein.	MRC1 domain-containing protein.	0.902
A0A2L2T708	A0A2L2TSB0	ERCC4 domain-containing protein.	Uncharacterized protein.	0.511
A0A2L2TA17	A0A2L2T426	Cell division control protein; Belongs to the CDC6/cdc18 family.	Protein kinase domain-containing protein.	0.872
A0A2L2TA17	A0A2L2TBF4	Cell division control protein; Belongs to the CDC6/cdc18 family.	Protein kinase domain-containing protein.	0.901
A0A2L2TA17	A0A2L2TH12	Cell division control protein; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.599