(55 nodes) Regulation of cytoskeleton organization network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2TXK5	Uncharacterized protein. (299 aa)
	A0A2L2TW86	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (958 aa)
	A0A2L2TW78	WH2 domain-containing protein. (418 aa)
	A0A2L2TVU0	Uncharacterized protein. (480 aa)
	A0A2L2TVP0	Zn(2)-C6 fungal-type domain-containing protein. (435 aa)
	A0A2L2TV95	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	A0A2L2TUM4	Zn(2)-C6 fungal-type domain-containing protein. (452 aa)
	A0A2L2TUK1	Uncharacterized protein. (791 aa)
	A0A2L2SW04	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
	A0A2L2SW39	Uncharacterized protein. (610 aa)
	A0A2L2SUL0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	A0A2L2SUK8	Uncharacterized protein. (656 aa)
	A0A2L2STN8	Zn(2)-C6 fungal-type domain-containing protein. (889 aa)
	A0A2L2SSY6	ADF-H domain-containing protein. (146 aa)
	A0A2L2SSC6	Spindle pole body component. (967 aa)
	A0A2L2SND3	Uncharacterized protein. (1200 aa)
	A0A2L2SMV6	Uncharacterized protein. (240 aa)
	A0A2L2SW74	Uncharacterized protein. (396 aa)
	A0A2L2SYD0	AIP3 domain-containing protein. (1029 aa)
	A0A2L2T047	Uncharacterized protein. (199 aa)
	A0A2L2T0F9	Coronin; Belongs to the WD repeat coronin family. (594 aa)
	A0A2L2T0U0	DUF4045 domain-containing protein. (1558 aa)
	A0A2L2T107	SH3 domain-containing protein. (271 aa)
	A0A2L2T1P7	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (202 aa)
	A0A2L2T1Z9	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (323 aa)
	A0A2L2T331	Uncharacterized protein. (832 aa)
	A0A2L2T3P7	C2H2-type domain-containing protein. (629 aa)
	A0A2L2T3U7	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (192 aa)
	A0A2L2T4N2	N-acetyltransferase domain-containing protein. (190 aa)
	A0A2L2T5H4	Zn(2)-C6 fungal-type domain-containing protein. (434 aa)
	A0A2L2T7W9	Uncharacterized protein. (219 aa)
	A0A2L2T856	ADF-H domain-containing protein. (142 aa)
	A0A2L2T8K9	TYR_PHOSPHATASE_2 domain-containing protein. (634 aa)
	A0A2L2T9J0	Zn(2)-C6 fungal-type domain-containing protein. (406 aa)
	A0A2L2T9L3	Uncharacterized protein. (265 aa)
	A0A2L2T9N8	Uncharacterized protein. (332 aa)
	A0A2L2TAE4	WD_REPEATS_REGION domain-containing protein. (610 aa)
	A0A2L2TD69	Uncharacterized protein. (143 aa)
	A0A2L2TDB4	Uncharacterized protein. (1755 aa)
	A0A2L2TDP3	Helo_like_N domain-containing protein. (513 aa)
	A0A2L2TDY0	Uncharacterized protein. (332 aa)
	A0A2L2TFW7	Uncharacterized protein. (951 aa)
	A0A2L2TG86	Uncharacterized protein. (618 aa)
	A0A2L2THB1	Uncharacterized protein. (206 aa)
	A0A2L2TIN5	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (131 aa)
	A0A2L2TKJ1	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
	A0A2L2TL05	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1221 aa)
	A0A2L2TL93	Uncharacterized protein. (270 aa)
	A0A2L2TLE1	Ras-GAP domain-containing protein. (779 aa)
	A0A2L2TNB5	WD_REPEATS_REGION domain-containing protein. (317 aa)
	A0A2L2TNC9	E3 ubiquitin-protein ligase. (810 aa)
	A0A2L2TP07	Zn(2)-C6 fungal-type domain-containing protein. (465 aa)
	A0A2L2TQH7	Uncharacterized protein. (195 aa)
	A0A2L2TY33	Adenylyl cyclase-associated protein; Belongs to the CAP family. (565 aa)
	A0A2L2TUB5	Uncharacterized protein. (187 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SMV6	A0A2L2SYD0	Uncharacterized protein.	AIP3 domain-containing protein.	0.606
A0A2L2SMV6	A0A2L2TDB4	Uncharacterized protein.	Uncharacterized protein.	0.437
A0A2L2SMV6	A0A2L2TVU0	Uncharacterized protein.	Uncharacterized protein.	0.531
A0A2L2SMV6	A0A2L2TW86	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.946
A0A2L2SND3	A0A2L2SW04	Uncharacterized protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.819
A0A2L2SND3	A0A2L2T3P7	Uncharacterized protein.	C2H2-type domain-containing protein.	0.819
A0A2L2SND3	A0A2L2T9L3	Uncharacterized protein.	Uncharacterized protein.	0.819
A0A2L2SND3	A0A2L2TG86	Uncharacterized protein.	Uncharacterized protein.	0.819
A0A2L2SND3	A0A2L2TKJ1	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.967
A0A2L2SSY6	A0A2L2SW39	ADF-H domain-containing protein.	Uncharacterized protein.	0.683
A0A2L2SSY6	A0A2L2T1P7	ADF-H domain-containing protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.421
A0A2L2SSY6	A0A2L2T1Z9	ADF-H domain-containing protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.448
A0A2L2SSY6	A0A2L2TDY0	ADF-H domain-containing protein.	Uncharacterized protein.	0.491
A0A2L2SSY6	A0A2L2TIN5	ADF-H domain-containing protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.426
A0A2L2SSY6	A0A2L2TKJ1	ADF-H domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.706
A0A2L2SSY6	A0A2L2TL05	ADF-H domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.466
A0A2L2SSY6	A0A2L2TY33	ADF-H domain-containing protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.913
A0A2L2STN8	A0A2L2SW04	Zn(2)-C6 fungal-type domain-containing protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.464
A0A2L2STN8	A0A2L2T047	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.524
A0A2L2STN8	A0A2L2T3P7	Zn(2)-C6 fungal-type domain-containing protein.	C2H2-type domain-containing protein.	0.464