(27 nodes) Transcription preinitiation complex assembly network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	A0A2L2TFQ4	TFIIB-type domain-containing protein. (350 aa)
	A0A2L2U167	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (120 aa)
	A0A2L2TYV6	Zn(2)-C6 fungal-type domain-containing protein. (686 aa)
	A0A2L2TXF2	TAFII28 domain-containing protein. (323 aa)
	A0A2L2TVV9	Uncharacterized protein. (254 aa)
	A0A2L2TVQ1	Uncharacterized protein. (439 aa)
	A0A2L2TUN7	PHD domain-containing protein. (715 aa)
	A0A2L2TTK1	Uncharacterized protein. (307 aa)
	A0A2L2TT12	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (674 aa)
	A0A2L2TMR0	Zn(2)-C6 fungal-type domain-containing protein. (738 aa)
	A0A2L2TMN2	TFIID_20kDa domain-containing protein. (698 aa)
	A0A2L2TMD9	Uncharacterized protein. (402 aa)
	A0A2L2TLK9	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (190 aa)
	A0A2L2TKJ7	CBFD_NFYB_HMF domain-containing protein. (329 aa)
	A0A2L2TK94	Uncharacterized protein. (364 aa)
	A0A2L2TGP8	DUF3591 domain-containing protein. (1221 aa)
	A0A2L2TDC4	Uncharacterized protein. (169 aa)
	A0A2L2SN37	SANT domain-containing protein. (592 aa)
	A0A2L2SRI3	CBFD_NFYB_HMF domain-containing protein. (150 aa)
	A0A2L2SXI1	Uncharacterized protein. (760 aa)
	A0A2L2SY99	TAF domain-containing protein. (463 aa)
	A0A2L2SZ21	Zn(2)-C6 fungal-type domain-containing protein. (657 aa)
	A0A2L2T287	TAFII55_N domain-containing protein. (476 aa)
	A0A2L2T469	Zn(2)-C6 fungal-type domain-containing protein. (709 aa)
	A0A2L2T490	Zn(2)-C6 fungal-type domain-containing protein. (710 aa)
	A0A2L2T4R0	Uncharacterized protein. (361 aa)
	A0A2L2T5A9	Fungal_trans domain-containing protein. (717 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SN37	A0A2L2SXI1	SANT domain-containing protein.	Uncharacterized protein.	0.996
A0A2L2SN37	A0A2L2TFQ4	SANT domain-containing protein.	TFIIB-type domain-containing protein.	0.428
A0A2L2SN37	A0A2L2TGP8	SANT domain-containing protein.	DUF3591 domain-containing protein.	0.446
A0A2L2SN37	A0A2L2TTK1	SANT domain-containing protein.	Uncharacterized protein.	0.741
A0A2L2SRI3	A0A2L2TFQ4	CBFD_NFYB_HMF domain-containing protein.	TFIIB-type domain-containing protein.	0.529
A0A2L2SRI3	A0A2L2TKJ7	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.987
A0A2L2SXI1	A0A2L2SN37	Uncharacterized protein.	SANT domain-containing protein.	0.996
A0A2L2SXI1	A0A2L2TFQ4	Uncharacterized protein.	TFIIB-type domain-containing protein.	0.528
A0A2L2SXI1	A0A2L2TMD9	Uncharacterized protein.	Uncharacterized protein.	0.457
A0A2L2SXI1	A0A2L2TTK1	Uncharacterized protein.	Uncharacterized protein.	0.808
A0A2L2SY99	A0A2L2T287	TAF domain-containing protein.	TAFII55_N domain-containing protein.	0.998
A0A2L2SY99	A0A2L2T4R0	TAF domain-containing protein.	Uncharacterized protein.	0.839
A0A2L2SY99	A0A2L2TDC4	TAF domain-containing protein.	Uncharacterized protein.	0.997
A0A2L2SY99	A0A2L2TFQ4	TAF domain-containing protein.	TFIIB-type domain-containing protein.	0.935
A0A2L2SY99	A0A2L2TGP8	TAF domain-containing protein.	DUF3591 domain-containing protein.	0.998
A0A2L2SY99	A0A2L2TK94	TAF domain-containing protein.	Uncharacterized protein.	0.909
A0A2L2SY99	A0A2L2TLK9	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.997
A0A2L2SY99	A0A2L2TMN2	TAF domain-containing protein.	TFIID_20kDa domain-containing protein.	0.998
A0A2L2SY99	A0A2L2TT12	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.648
A0A2L2SY99	A0A2L2TTK1	TAF domain-containing protein.	Uncharacterized protein.	0.832