(76 nodes) Actin cytoskeleton network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2SNS4	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (695 aa)
	A0A2L2SP78	Uncharacterized protein. (208 aa)
	A0A2L2SPZ3	Uncharacterized protein. (284 aa)
	A0A2L2SQN4	UDENN domain-containing protein. (729 aa)
	A0A2L2SR73	Uncharacterized protein. (891 aa)
	A0A2L2SRB1	Uncharacterized protein. (375 aa)
	A0A2L2SSH4	Uncharacterized protein. (397 aa)
	A0A2L2ST29	Uncharacterized protein. (668 aa)
	A0A2L2STH4	Uncharacterized protein. (194 aa)
	A0A2L2STK5	Uncharacterized protein. (1304 aa)
	A0A2L2STK8	Peptidase_M3 domain-containing protein. (739 aa)
	A0A2L2SU18	Uncharacterized protein. (1465 aa)
	A0A2L2SU92	Calponin-homology (CH) domain-containing protein. (674 aa)
	A0A2L2SUK8	Uncharacterized protein. (656 aa)
	A0A2L2SUL0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	A0A2L2SUZ3	SH3 domain-containing protein. (1270 aa)
	A0A2L2SW04	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
	A0A2L2SXC8	Uncharacterized protein. (423 aa)
	A0A2L2SY28	STAS domain-containing protein. (782 aa)
	A0A2L2T0F9	Coronin; Belongs to the WD repeat coronin family. (594 aa)
	A0A2L2T105	Uncharacterized protein; Belongs to the actin family. (555 aa)
	A0A2L2T1P7	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (202 aa)
	A0A2L2T1X4	MFS domain-containing protein. (542 aa)
	A0A2L2T1Z9	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (323 aa)
	A0A2L2T2T1	TGc domain-containing protein. (675 aa)
	A0A2L2T325	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1583 aa)
	A0A2L2T3U7	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (192 aa)
	A0A2L2T6J6	Uncharacterized protein. (161 aa)
	A0A2L2T6R3	Uncharacterized protein. (437 aa)
	A0A2L2T7A4	Uncharacterized protein. (419 aa)
	A0A2L2T7D6	Myosin motor domain-containing protein. (1781 aa)
	A0A2L2T7U0	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1864 aa)
	A0A2L2T856	ADF-H domain-containing protein. (142 aa)
	A0A2L2T8M3	Uncharacterized protein. (229 aa)
	A0A2L2T909	EH domain-containing protein. (614 aa)
	A0A2L2T9L3	Uncharacterized protein. (265 aa)
	A0A2L2T9P9	Uncharacterized protein. (922 aa)
	A0A2L2TAH2	Uncharacterized protein. (717 aa)
	A0A2L2TAQ3	Uncharacterized protein. (553 aa)
	A0A2L2TBX7	Protein kinase domain-containing protein. (1017 aa)
	A0A2L2TCX3	Uncharacterized protein. (808 aa)
	A0A2L2TDD4	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (393 aa)
	A0A2L2TDY0	Uncharacterized protein. (332 aa)
	A0A2L2TE86	Uncharacterized protein. (476 aa)
	A0A2L2TF17	SH3 domain-containing protein. (1255 aa)
	A0A2L2TF60	Uncharacterized protein. (743 aa)
	A0A2L2TFC5	Uncharacterized protein. (649 aa)
	A0A2L2TG86	Uncharacterized protein. (618 aa)
	A0A2L2THB0	Uncharacterized protein. (428 aa)
	A0A2L2THK4	Uncharacterized protein. (324 aa)
	A0A2L2TJF6	Uncharacterized protein. (686 aa)
	A0A2L2TJK5	Uncharacterized protein. (980 aa)
	A0A2L2TKJ1	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
	A0A2L2TKM3	Uncharacterized protein. (424 aa)
	A0A2L2TL05	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1221 aa)
	A0A2L2TMR6	Zn(2)-C6 fungal-type domain-containing protein. (739 aa)
	A0A2L2TN18	Uncharacterized protein. (388 aa)
	A0A2L2TNM0	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2398 aa)
	A0A2L2TNT6	SAC domain-containing protein. (1308 aa)
	A0A2L2TPU9	Uncharacterized protein. (452 aa)
	A0A2L2TQA5	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (455 aa)
	A0A2L2TQP9	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (390 aa)
	A0A2L2TR73	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (387 aa)
	A0A2L2TS67	Uncharacterized protein. (1247 aa)
	A0A2L2TSU9	C2 domain-containing protein. (869 aa)
	A0A2L2TUK1	Uncharacterized protein. (791 aa)
	A0A2L2TV95	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	A0A2L2TW56	Uncharacterized protein. (860 aa)
	A0A2L2TW78	WH2 domain-containing protein. (418 aa)
	A0A2L2TX98	Uncharacterized protein. (1758 aa)
	A0A2L2TYB8	Uncharacterized protein. (950 aa)
	A0A2L2TZC0	UBR-type domain-containing protein. (549 aa)
	A0A2L2U0J8	Uncharacterized protein. (737 aa)
	A0A2L2U1A3	Uncharacterized protein. (911 aa)
	A0A2L2U1D6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (506 aa)
	A0A2L2U300	Uncharacterized protein; Belongs to the actin family. (439 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SNS4	A0A2L2SRB1	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.567
A0A2L2SNS4	A0A2L2SU18	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.506
A0A2L2SNS4	A0A2L2TBX7	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Protein kinase domain-containing protein.	0.602
A0A2L2SNS4	A0A2L2TNT6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SAC domain-containing protein.	0.430
A0A2L2SNS4	A0A2L2TS67	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.506
A0A2L2SNS4	A0A2L2U0J8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.489
A0A2L2SP78	A0A2L2SRB1	Uncharacterized protein.	Uncharacterized protein.	0.408
A0A2L2SP78	A0A2L2TFC5	Uncharacterized protein.	Uncharacterized protein.	0.478
A0A2L2SPZ3	A0A2L2SR73	Uncharacterized protein.	Uncharacterized protein.	0.786
A0A2L2SPZ3	A0A2L2SRB1	Uncharacterized protein.	Uncharacterized protein.	0.914
A0A2L2SPZ3	A0A2L2STK5	Uncharacterized protein.	Uncharacterized protein.	0.538
A0A2L2SPZ3	A0A2L2SU92	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.788
A0A2L2SPZ3	A0A2L2T105	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.744
A0A2L2SPZ3	A0A2L2T2T1	Uncharacterized protein.	TGc domain-containing protein.	0.474
A0A2L2SPZ3	A0A2L2T325	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.748
A0A2L2SPZ3	A0A2L2T6J6	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A2L2SPZ3	A0A2L2TFC5	Uncharacterized protein.	Uncharacterized protein.	0.533
A0A2L2SPZ3	A0A2L2THK4	Uncharacterized protein.	Uncharacterized protein.	0.588
A0A2L2SPZ3	A0A2L2TL05	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.632
A0A2L2SPZ3	A0A2L2TNM0	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.997