(40 nodes) Branched-chain amino acid catabolism network (Fusarium venenatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A2L2SUM8	Uncharacterized protein. (340 aa)
	A0A2L2U3Q8	Uncharacterized protein. (262 aa)
	A0A2L2U177	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (333 aa)
	A0A2L2TTV6	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
	A0A2L2TTI0	Uncharacterized protein. (168 aa)
	A0A2L2TT40	Uncharacterized protein. (302 aa)
	A0A2L2TRI5	Uncharacterized protein. (290 aa)
	A0A2L2TQ31	Uncharacterized protein. (325 aa)
	A0A2L2TMK2	Uncharacterized protein. (262 aa)
	A0A2L2TMG0	Protein-serine/threonine kinase. (423 aa)
	A0A2L2TLB9	Uncharacterized protein. (294 aa)
	A0A2L2TKP5	Zn(2)-C6 fungal-type domain-containing protein. (683 aa)
	A0A2L2TJJ2	Uncharacterized protein. (412 aa)
	A0A2L2TI24	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (408 aa)
	A0A2L2THL9	Uncharacterized protein. (319 aa)
	A0A2L2TGY9	Uncharacterized protein. (274 aa)
	A0A2L2TGQ5	Protein-serine/threonine kinase. (451 aa)
	A0A2L2TGL8	Uncharacterized protein. (316 aa)
	A0A2L2TE74	Uncharacterized protein. (383 aa)
	A0A2L2TE28	Uncharacterized protein. (343 aa)
	A0A2L2TDV6	Uncharacterized protein. (380 aa)
	A0A2L2TCC0	Aldedh domain-containing protein. (520 aa)
	A0A2L2TAM3	NAD_binding_2 domain-containing protein. (296 aa)
	A0A2L2TAC8	Uncharacterized protein. (281 aa)
	A0A2L2T9U8	Uncharacterized protein. (452 aa)
	A0A2L2T9S1	Uncharacterized protein. (382 aa)
	A0A2L2T6F7	Uncharacterized protein. (585 aa)
	A0A2L2T600	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (458 aa)
	A0A2L2T3J5	Formyl_trans_C domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. (744 aa)
	A0A2L2T350	Aldedh domain-containing protein. (567 aa)
	A0A2L2T2Z2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (408 aa)
	A0A2L2T273	Beta_helix domain-containing protein. (399 aa)
	A0A2L2T1W3	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (505 aa)
	A0A2L2T1H7	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
	A0A2L2SY35	Uncharacterized protein. (317 aa)
	A0A2L2SWB9	Transket_pyr domain-containing protein. (404 aa)
	A0A2L2SVS7	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	A0A2L2SUV1	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (1204 aa)
	A0A2L2STN4	Uncharacterized protein. (426 aa)
	A0A2L2SMM8	Pyr_redox_2 domain-containing protein. (316 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2L2SMM8	A0A2L2SUM8	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.777
A0A2L2SMM8	A0A2L2SUV1	Pyr_redox_2 domain-containing protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.477
A0A2L2SMM8	A0A2L2SVS7	Pyr_redox_2 domain-containing protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.477
A0A2L2SMM8	A0A2L2T1W3	Pyr_redox_2 domain-containing protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.580
A0A2L2SMM8	A0A2L2T3J5	Pyr_redox_2 domain-containing protein.	Formyl_trans_C domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.477
A0A2L2SMM8	A0A2L2T6F7	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.714
A0A2L2SMM8	A0A2L2TAC8	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.477
A0A2L2SMM8	A0A2L2TAM3	Pyr_redox_2 domain-containing protein.	NAD_binding_2 domain-containing protein.	0.777
A0A2L2SMM8	A0A2L2TGL8	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.447
A0A2L2SMM8	A0A2L2TGY9	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.477
A0A2L2SMM8	A0A2L2THL9	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.447
A0A2L2SMM8	A0A2L2TLB9	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.447
A0A2L2SMM8	A0A2L2TMK2	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.607
A0A2L2SMM8	A0A2L2TRI5	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.477
A0A2L2SMM8	A0A2L2TT40	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.477
A0A2L2SMM8	A0A2L2TTV6	Pyr_redox_2 domain-containing protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.710
A0A2L2SMM8	A0A2L2U177	Pyr_redox_2 domain-containing protein.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.777
A0A2L2SMM8	A0A2L2U3Q8	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.580
A0A2L2STN4	A0A2L2SUV1	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.659
A0A2L2STN4	A0A2L2SVS7	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.948