(34 nodes) Nervous system development network (Fusarium venenatum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

Your Input:
	A0A2L2TWC6	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (584 aa)
	A0A2L2TX71	Uncharacterized protein. (227 aa)
	A0A2L2TY09	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (238 aa)
	A0A2L2TYC9	Uncharacterized protein. (139 aa)
	A0A2L2SMH6	Amidohydro-rel domain-containing protein. (453 aa)
	A0A2L2SQE8	Rad60-SLD_2 domain-containing protein. (262 aa)
	A0A2L2STN8	Zn(2)-C6 fungal-type domain-containing protein. (889 aa)
	A0A2L2SUE2	Zn(2)-C6 fungal-type domain-containing protein. (741 aa)
	A0A2L2SUV8	Protein kinase domain-containing protein. (526 aa)
	A0A2L2SV62	Zn(2)-C6 fungal-type domain-containing protein. (484 aa)
	A0A2L2SW39	Uncharacterized protein. (610 aa)
	A0A2L2SWI0	Protein kinase domain-containing protein. (646 aa)
	A0A2L2U472	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (172 aa)
	A0A2L2U384	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	A0A2L2U341	Amidohydro-rel domain-containing protein. (530 aa)
	A0A2L2SWK7	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (713 aa)
	A0A2L2SYW4	PH domain-containing protein. (417 aa)
	A0A2L2T1Q7	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (987 aa)
	A0A2L2T3F7	Uncharacterized protein. (114 aa)
	A0A2L2T560	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (139 aa)
	A0A2L2TZ74	HET domain-containing protein. (1229 aa)
	A0A2L2TA81	Protein kinase domain-containing protein. (520 aa)
	A0A2L2TBH1	Homeobox domain-containing protein. (495 aa)
	A0A2L2TC17	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	A0A2L2TDK8	Uncharacterized protein. (199 aa)
	A0A2L2TGF3	Amidohydro-rel domain-containing protein. (452 aa)
	A0A2L2THI8	Zn(2)-C6 fungal-type domain-containing protein. (524 aa)
	A0A2L2TIG4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (747 aa)
	A0A2L2TIY7	Uncharacterized protein. (490 aa)
	A0A2L2TNU5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (136 aa)
	A0A2L2TPR7	Uncharacterized protein. (140 aa)
	A0A2L2TTY7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	A0A2L2TUJ9	Amidohydro-rel domain-containing protein. (377 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (885 aa)

Your Current Organism:

Fusarium venenatum

NCBI taxonomy Id: 56646
Other names: CBS 458.93, F. venenatum, Fusarium venetum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2L2SMH6	A0A2L2T1Q7	A0A2L2SMH6	A0A2L2T1Q7	Amidohydro-rel domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.444
A0A2L2SQE8	A0A2L2T1Q7	A0A2L2SQE8	A0A2L2T1Q7	Rad60-SLD_2 domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.957
A0A2L2SQE8	A0A2L2TC17	A0A2L2SQE8	A0A2L2TC17	Rad60-SLD_2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.962
A0A2L2SQE8	A0A2L2TDK8	A0A2L2SQE8	A0A2L2TDK8	Rad60-SLD_2 domain-containing protein.	Uncharacterized protein.	0.622
A0A2L2SQE8	A0A2L2TTY7	A0A2L2SQE8	A0A2L2TTY7	Rad60-SLD_2 domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.538
A0A2L2SQE8	A0A2L2TWC6	A0A2L2SQE8	A0A2L2TWC6	Rad60-SLD_2 domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.972
A0A2L2SQE8	A0A2L2TY09	A0A2L2SQE8	A0A2L2TY09	Rad60-SLD_2 domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.863
A0A2L2SQE8	A0A2L2U384	A0A2L2SQE8	A0A2L2U384	Rad60-SLD_2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.968
A0A2L2STN8	A0A2L2TC17	A0A2L2STN8	A0A2L2TC17	Zn(2)-C6 fungal-type domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.594
A0A2L2STN8	A0A2L2TDK8	A0A2L2STN8	A0A2L2TDK8	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.524
A0A2L2SUE2	A0A2L2T1Q7	A0A2L2SUE2	A0A2L2T1Q7	Zn(2)-C6 fungal-type domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.538
A0A2L2SUV8	A0A2L2SWI0	A0A2L2SUV8	A0A2L2SWI0	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.651
A0A2L2SUV8	A0A2L2TA81	A0A2L2SUV8	A0A2L2TA81	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.659
A0A2L2SUV8	A0A2L2TDK8	A0A2L2SUV8	A0A2L2TDK8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.552
A0A2L2SUV8	A0A2L2TTY7	A0A2L2SUV8	A0A2L2TTY7	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.854
A0A2L2SV62	A0A2L2T1Q7	A0A2L2SV62	A0A2L2T1Q7	Zn(2)-C6 fungal-type domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.538
A0A2L2SW39	A0A2L2TC17	A0A2L2SW39	A0A2L2TC17	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.869
A0A2L2SW39	A0A2L2TDK8	A0A2L2SW39	A0A2L2TDK8	Uncharacterized protein.	Uncharacterized protein.	0.972
A0A2L2SW39	A0A2L2TY09	A0A2L2SW39	A0A2L2TY09	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.735
A0A2L2SW39	SLX4	A0A2L2SW39	A0A2L2TVP9	Uncharacterized protein.	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.952