Your Input: | |
| | EPF21048.1 | Hypothetical protein; KEGG: ebi:EbC_02520 1.7e-30 tufA; elongation factor Tu-A; K02358 elongation factor EF-Tu; Psort location: Cytoplasmic, score: 9.26. (67 aa) |
| | EPF20954.1 | KEGG: pct:PC1_0198 1.6e-98 translation elongation factor Tu; K02358 elongation factor EF-Tu; Psort location: Cytoplasmic, score: 9.97. (193 aa) |
| | nusG | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional anti [...] (181 aa) |
| | rplK | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | rplJ | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | rplL | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa) |
| | EPF20319.1 | Ribosomal large subunit pseudouridine synthase F; KEGG: ebi:EbC_00380 1.1e-131 pseudouridine synthase K06182; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. (293 aa) |
| | dusA | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (313 aa) |
| | efp | Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | epmA | lysine--tRNA ligase-like protein GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (340 aa) |
| | EPF20494.1 | Putative pyridoxal phosphate-dependent enzyme. (377 aa) |
| | rsmI | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (288 aa) |
| | queG | Putative iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (379 aa) |
| | EPF20525.1 | Hydrolase, P-loop family. (153 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (314 aa) |
| | rlmB | RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily. (243 aa) |
| | rpsF | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa) |
| | rpsR | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rplI | Ribosomal protein L9; Binds to the 23S rRNA. (149 aa) |
| | rlmG | Ribosomal RNA large subunit methyltransferase G; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (378 aa) |
| | EPF20631.1 | Sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (614 aa) |
| | rpsU | Ribosomal protein S21; KEGG: sew:SeSA_A3399 3.4e-32 rpsU; 30S ribosomal protein S21 K02970; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | tsaD | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (337 aa) |
| | cca | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (420 aa) |
| | rsmC | Ribosomal RNA small subunit methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (343 aa) |
| | EPF20695.1 | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (147 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | lplA | Lipoate--protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. (338 aa) |
| | EPF20713.1 | ATP-binding cassette protein, ChvD family. (548 aa) |
| | trmJ | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (228 aa) |
| | EPF20745.1 | Ribosomal protein S20. (61 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa) |
| | EPF20753.1 | Threonine/alanine tRNA ligase second additional domain protein. (209 aa) |
| | EPF20759.1 | Transcriptional activatory protein CaiF. (131 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (274 aa) |
| | EPF20784.1 | Pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (219 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa) |
| | EPF20860.1 | Putative polynucleotide adenylyltransferase; KEGG: ctu:Ctu_07740 2.2e-172 pcnB; poly(A) polymerase I K00970; Psort location: Cytoplasmic, score: 9.97; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (355 aa) |
| | gluQ | Glutamyl-queuosine tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (294 aa) |
| | EPF20865.1 | KEGG: eok:G2583_0152 0. hrpB; ATP-dependent helicase HrpB; K03579 ATP-dependent helicase HrpB; Psort location: CytoplasmicMembrane, score: 9.27. (836 aa) |
| | rpsB | Ribosomal protein S2; KEGG: apb:SAR116_0519 1.3e-73 ribosomal protein S2 K02967; Psort location: Cytoplasmic, score: 9.97; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (283 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (173 aa) |
| | EPF20893.1 | DNA-binding protein; KEGG: hip:CGSHiEE_07435 4.0e-15 leuS; leucyl-tRNA synthetase K06142; Psort location: Periplasmic, score: 10.00; Belongs to the skp family. (184 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (435 aa) |
| | EPF20908.1 | KEGG: reh:H16_A3611 1.3e-32 pth2; peptidyl-tRNA hydrolase K05969. (140 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (572 aa) |
| | EPF20074.1 | Amidohydrolase, AtzE family; KEGG: eca:ECA3499 7.2e-158 amidase K02433; Psort location: Cytoplasmic, score: 9.26. (458 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (375 aa) |
| | nusB | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa) |
| | EPF19125.1 | Protein BolA; Belongs to the BolA/IbaG family. (117 aa) |
| | EPF19201.1 | Hypothetical protein. (70 aa) |
| | EPF18392.1 | RNA polymerase sigma factor, FliA/WhiG family; KEGG: rpi:Rpic_4070 1.1e-28 fliA; flagellar biosynthesis sigma factor K02405; Psort location: Cytoplasmic, score: 8.96. (229 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) |
| | lipB | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (192 aa) |
| | rlmH | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa) |
| | leuS | leucine--tRNA ligase; KEGG: cko:CKO_02514 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | ybeY | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (155 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (494 aa) |
| | glnS | glutamine--tRNA ligase; KEGG: seh:SeHA_C0805 3.4e-279 glnS; glutaminyl-tRNA synthetase K01886; Psort location: Cytoplasmic, score: 9.97. (555 aa) |
| | dusC | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (311 aa) |
| | EPF18599.1 | KEGG: reh:H16_A2563 4.6e-14 rpoE1; RNA polymerase sigma factor RpoE K03088; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa) |
| | EPF18609.1 | Putative N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; KEGG: vsa:VSAL_I1658 6.7e-116 glycosylasparaginase; Psort location: Periplasmic, score: 9.44. (322 aa) |
| | rlmF | rRNA adenine N-6-methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (333 aa) |
| | EPF18630.1 | KEGG: sno:Snov_3030 0.0054 putative transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 8.96. (184 aa) |
| | rimK | alpha-L-glutamate ligase, RimK family; KEGG: ddd:Dda3937_03479 3.9e-111 rimK; ribosomal protein S6 modification protein K05844; Psort location: Cytoplasmic, score: 9.97; Belongs to the RimK family. (278 aa) |
| | rlmC | 23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (378 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | EPF18702.1 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | cmoM | Methyltransferase domain protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (258 aa) |
| | asnS | asparagine--tRNA ligase; KEGG: cko:CKO_02135 6.4e-237 asnC; asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00. (466 aa) |
| | rlmL | Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (707 aa) |
| | rlmI | 23S rRNA methyltransferase; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. (396 aa) |
| | EPF18762.1 | Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system. (115 aa) |
| | EPF18097.1 | Rhodanese-like protein; Belongs to the UPF0176 family. (349 aa) |
| | EPF18107.1 | Ribosomal-protein-alanine acetyltransferase. (198 aa) |
| | rne | Rne RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1071 aa) |
| | EPF18130.1 | Pseudouridine synthase, RluA family. (155 aa) |
| | rpmF | Ribosomal protein L32; KEGG: apb:SAR116_0011 5.6e-09 ribosomal protein L32 K02911; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL32 family. (56 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (384 aa) |
| | EPF18195.1 | KEGG: esa:ESA_02210 4.0e-93 hypothetical protein; K06181 ribosomal large subunit pseudouridine synthase E; Psort location: Cytoplasmic, score: 9.26. (210 aa) |
| | EPF18244.1 | Signal peptide peptidase SppA; KEGG: ctu:Ctu_18080 7.2e-277 sppA; protease 4 K04773; Psort location: CytoplasmicMembrane, score: 10.00. (616 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (622 aa) |
| | EPF17745.1 | Translation initiation factor IF-3; Belongs to the IF-3 family. (113 aa) |
| | rpmI | Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | rplT | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | pheS | phenylalanine--tRNA ligase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | pheT | phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | EPF17780.1 | CAAX amino terminal protease family protein. (276 aa) |
| | rnt | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (219 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (428 aa) |
| | EPF17901.1 | Ribosomal-protein-serine acetyltransferase. (184 aa) |
| | EPF17628.1 | Protein mlc; KEGG: ctu:Ctu_22200 6.2e-184 mlc; protein mlc; Psort location: Cytoplasmic, score: 9.97. (405 aa) |
| | EPF17646.1 | Phenylacetic acid degradation operon negative regulatory protein PaaX. (309 aa) |
| | EPF17649.1 | KEGG: ecx:EcHS_A1496 0. hrpA; ATP-dependent RNA helicase HrpA; K03578 ATP-dependent helicase HrpA; Psort location: Cytoplasmic, score: 8.96. (1309 aa) |
| | EPF17388.1 | Acetyltransferase, GNAT family; KEGG: reh:H16_A0240 1.0e-16 acetyltransferase. (170 aa) |
| | EPF16840.1 | Metallo-beta-lactamase domain protein; KEGG: aac:Aaci_0647 2.8e-11 ribonuclease Z K00784; Psort location: Cytoplasmic, score: 8.96. (256 aa) |
| | EPF16886.1 | Sigma-70 region 2; KEGG: reh:H16_A2923 4.3e-34 rpoE4; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K03088; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | EPF16943.1 | Sigma-70 region 2; KEGG: psa:PST_3692 4.1e-05 PpiC-type peptidyl-prolyl cis-trans isomerase; K03769 peptidyl-prolyl cis-trans isomerase C; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | EPF17002.1 | KEGG: ctu:Ctu_21870 4.6e-227 allophanate hydrolase; K02433 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit A; Psort location: CytoplasmicMembrane, score: 8.46. (598 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (222 aa) |
| | ttcA | PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (311 aa) |
| | EPF16633.1 | Putative translation initiation factor SUI1; Psort location: Cytoplasmic, score: 8.96. (108 aa) |
| | EPF16649.1 | KEGG: spt:SPA1157 3.6e-140 yciL; 23S rRNA pseudouridylate synthase B; K06178 ribosomal large subunit pseudouridine synthase B; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. (295 aa) |
| | EPF16651.1 | KEGG: apb:SAR116_0691 6.5e-11 SUA5/YciO/YrdC/YwlC family protein K07566; Psort location: Cytoplasmic, score: 8.96; Belongs to the SUA5 family. (206 aa) |
| | EPF16652.1 | PHP domain protein; KEGG: hip:CGSHiEE_04580 1.9e-70 fumC; fumarate hydratase K07053; Psort location: Cytoplasmic, score: 9.97. (293 aa) |
| | EPF16698.1 | Sigma-70 region 2; KEGG: bpu:BPUM_0902 7.1e-09 sigM; RNA polymerase sigma factor SigM K03088; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa) |
| | EPF16713.1 | DsrE/DsrF-like family protein; KEGG: ctu:Ctu_24130 3.8e-49 ychN; protein YchN K06039. (117 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | pth | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (194 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (369 aa) |
| | EPF16229.1 | Universal bacterial protein YeaZ; KEGG: ecp:ECP_1750 6.2e-97 protease YeaZ K01423. (231 aa) |
| | rsmF | rRNA (cytosine-C(5)-)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. (482 aa) |
| | aspS | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (602 aa) |
| | cmoA | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa) |
| | cmoB | Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (323 aa) |
| | argS | arginine--tRNA ligase. (577 aa) |
| | fliA | Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (229 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (699 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa) |
| | EPF15842.1 | KEGG: ecl:EcolC_2807 8.9e-137 rimO; ribosomal protein S12 methylthiotransferase; Psort location: Cytoplasmic, score: 9.97. (280 aa) |
| | EPF15848.1 | L-asparaginase; KEGG: cko:CKO_02281 2.8e-124 L-asparaginase; K13051 beta-aspartyl-peptidase (threonine type). (317 aa) |
| | EPF15908.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (452 aa) |
| | EPF15915.1 | Elongation factor P; KEGG: sax:USA300HOU_1530 1.0e-23 efp; elongation factor P K02356; Psort location: Cytoplasmic, score: 9.97. (190 aa) |
| | EPF15928.1 | KEGG: enc:ECL_03502 4.5e-110 16S rRNA pseudouridylate synthase A; K06183 ribosomal small subunit pseudouridine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. (233 aa) |
| | EPF15929.1 | Helicase protein; KEGG: ddd:Dda3937_04324 3.9e-253 yejH; putative ATP-dependet helicase; Psort location: Cytoplasmic, score: 8.96. (586 aa) |
| | rplY | Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (271 aa) |
| | mnmC | tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (666 aa) |
| | EPF15574.1 | KEGG: spe:Spro_3940 1.8e-106 pseudouridine synthase; K06177 ribosomal large subunit pseudouridine synthase A; Psort location: Cytoplasmic, score: 9.97. (232 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa) |
| | tmcA | Acetyltransferase, GNAT family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (676 aa) |
| | cysS | cysteine--tRNA ligase; KEGG: cro:ROD_05581 1.6e-224 cysS; cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | selU | tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain. (365 aa) |
| | EPF15400.1 | YbaK/EbsC protein; KEGG: ent:Ent638_0960 1.9e-70 hypothetical protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | rpmJ | Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (46 aa) |
| | rpmE2 | Ribosomal protein L31; KEGG: apb:SAR116_2278 0.0023 ribosomal protein L31 K02909. (89 aa) |
| | hisS | histidine--tRNA ligase; KEGG: ctu:Ctu_31080 8.2e-205 hisS; histidyl-tRNA synthetase K01892; Psort location: Cytoplasmic, score: 10.00. (432 aa) |
| | rlmN | 23S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (387 aa) |
| | trmJ-2 | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (247 aa) |
| | tadA | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (229 aa) |
| | EPF15296.1 | Phage baseplate assembly protein V. (228 aa) |
| | EPF15312.1 | Ferredoxin; KEGG: pva:Pvag_2310 7.0e-34 yfhL; NADH dehydrogenase. (86 aa) |
| | EPF15317.1 | KEGG: enc:ECL_03906 1.6e-160 signal peptidase I; K03100 signal peptidase I; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the peptidase S26 family. (324 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | EPF15322.1 | KEGG: ctu:Ctu_31640 2.0e-91 rpoE; RNA polymerase sigma factor RpoE K03088; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa) |
| | EPF15325.1 | Methyltransferase small domain protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (256 aa) |
| | EPF15330.1 | RNA methyltransferase, TrmH family; KEGG: ctu:Ctu_31700 1.0e-110 yfiF; putative methyltransferase; K03214 RNA methyltransferase, TrmH family; Psort location: Cytoplasmic, score: 9.26; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (247 aa) |
| | EPF15334.1 | DTW domain protein; Psort location: Cytoplasmic, score: 9.26. (175 aa) |
| | EPF14910.1 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (326 aa) |
| | rplS | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (244 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (183 aa) |
| | rpsP | Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (94 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (160 aa) |
| | EPF15009.1 | Hypothetical protein; KEGG: tgo:TGME49_076860 0.0062 late embryogenesis abundant domain-containing protein. (119 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (783 aa) |
| | EPF13543.1 | tryptophan--tRNA ligase; KEGG: kpe:KPK_4890 4.8e-145 tryptophanyl-tRNA synthetase II K01867; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. (339 aa) |
| | rpoS | RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (330 aa) |
| | truD | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (348 aa) |
| | rlmD | 23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (458 aa) |
| | EPF13579.1 | RNA pseudouridine synthase. (259 aa) |
| | rlmM | Putative RNA 2'-O-ribose methyltransferase YgdE; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa) |
| | EPF13594.1 | ThiF family protein. (269 aa) |
| | EPF13658.1 | Hypothetical protein; KEGG: mga:MGA_0604 0.0039 trmE; tRNA modification GTPase TrmE K03650. (287 aa) |
| | EPF13674.1 | Sigma-70 region 2; KEGG: bpu:BPUM_0902 2.3e-10 sigM; RNA polymerase sigma factor SigM K03088; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa) |
| | EPF13683.1 | Hypothetical protein. (382 aa) |
| | lysS | lysine--tRNA ligase; KEGG: enc:ECL_04215 3.1e-253 lysyl-tRNA synthetase; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (293 aa) |
| | EPF13695.1 | Folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. (328 aa) |
| | EPF13757.1 | 16S rRNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (243 aa) |
| | yqgF | RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (139 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (239 aa) |
| | EPF13865.1 | Hypothetical protein; KEGG: sne:SPN23F_03230 0.0070 wchF; putative rhamnosyl transferase WchF; K12996 rhamnosyltransferase. (110 aa) |
| | EPF13884.1 | Hypothetical protein; KEGG: mga:MGA_0604 0.00090 trmE; tRNA modification GTPase TrmE K03650; Psort location: Cytoplasmic, score: 8.96. (268 aa) |
| | EPF13899.1 | Hypothetical protein; KEGG: hpc:HPPC_01425 0.0046 tgt; queuine tRNA-ribosyltransferase; Psort location: Cytoplasmic, score: 8.96. (219 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | EPF13922.1 | tRNA-(ms[2]io[6]A)-hydroxylase; KEGG: ent:Ent638_0461 3.6e-108 tRNA--hydroxylase; K06169 tRNA-(ms[2]io[6]A)-hydroxylase; Psort location: Cytoplasmic, score: 9.97. (266 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (719 aa) |
| | rpsO | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (314 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (897 aa) |
| | nusA | Transcription termination factor NusA; Participates in both transcription termination and antitermination. (495 aa) |
| | rlmE | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (209 aa) |
| | EPF13970.1 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 9.97. (97 aa) |
| | rpmA | Ribosomal protein L27; KEGG: apb:SAR116_1855 3.4e-25 ribosomal protein L27 K02899; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | EPF13994.1 | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa) |
| | rpsI | Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | EPF14026.1 | Ribonuclease G. (489 aa) |
| | dusB | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa) |
| | tsaC | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (190 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | rsmB | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (429 aa) |
| | EPF13253.1 | Ribosomal protein L17; KEGG: apb:SAR116_2416 6.0e-28 ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL17 family. (109 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa) |
| | rpsD | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | EPF13258.1 | Ribosomal protein L15; Psort location: Cytoplasmic, score: 9.26; Belongs to the universal ribosomal protein uL15 family. (73 aa) |
| | rpmD | Ribosomal protein L30; KEGG: apb:SAR116_2409 3.2e-13 ribosomal protein L30 K02907; Psort location: Cytoplasmic, score: 9.26. (59 aa) |
| | rpsE | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa) |
| | rplR | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rplF | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpsN | Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rplE | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rplX | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa) |
| | rplN | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rpmC | Ribosomal protein L29; KEGG: apb:SAR116_2399 6.9e-11 ribosomal protein L29 K02904; Psort location: Cytoplasmic, score: 9.26; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | rplP | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpsC | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) |
| | rplV | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa) |
| | rpsS | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplB | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (255 aa) |
| | rplW | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplD | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (201 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rpsJ | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | EPF13280.1 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; KEGG: shn:Shewana3_0417 1.2e-36 Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A K02654; Psort location: CytoplasmicMembrane, score: 10.00. (170 aa) |
| | EPF13283.1 | KEGG: pct:PC1_0198 1.6e-98 translation elongation factor Tu; K02358 elongation factor EF-Tu; Psort location: Cytoplasmic, score: 9.97. (193 aa) |
| | EPF13238.1 | Elongation factor Tu GTP binding domain protein; KEGG: cko:CKO_04745 5.3e-68 elongation factor Tu; K02358 elongation factor EF-Tu; Psort location: Cytoplasmic, score: 9.97. (133 aa) |
| | EPF13101.1 | Hypothetical protein; KEGG: xbo:XBJ1_4062 4.5e-30 tufA; protein chain elongation factor EF-Tu (duplicate of TufB); K02358 elongation factor EF-Tu; Psort location: Cytoplasmic, score: 9.26. (67 aa) |
| | fusA-2 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (704 aa) |
| | rpsG | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | tusB | Sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (95 aa) |
| | tusC | Sulfur relay protein TusC/DsrF; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa) |
| | tusD | Sulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. (128 aa) |
| | EPF13111.1 | KEGG: ctu:Ctu_38630 1.1e-101 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase K03775; Psort location: Cytoplasmic, score: 9.97. (207 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | nfuA | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa) |
| | panZ | Acetyltransferase, GNAT family; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family. (126 aa) |
| | rpoH | Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (284 aa) |
| | EPF12814.1 | RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (195 aa) |
| | tusA | Sulfur transfer protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. (81 aa) |
| | EPF12833.1 | Sigma-70 region 2; KEGG: psa:PST_3692 8.2e-11 PpiC-type peptidyl-prolyl cis-trans isomerase; K03769 peptidyl-prolyl cis-trans isomerase C; Psort location: Cytoplasmic, score: 9.26; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa) |
| | EPF12846.1 | KEGG: apb:SAR116_2461 4.0e-102 HI0933 family protein K07007. (397 aa) |
| | rsmJ | Hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA. (250 aa) |
| | rlmJ | Hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA. (280 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (462 aa) |
| | EPF12878.1 | KEGG: eci:UTI89_C4132 1.0e-247 selB; selenocysteinyl-tRNA-specific translation factor K03833; Psort location: Cytoplasmic, score: 9.97. (612 aa) |
| | fdhE | Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa) |
| | rpmH | Ribosomal protein L34; KEGG: rak:A1C_04775 2.3e-10 rpmH; 50S ribosomal protein L34 K02914; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (108 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | glyS | KEGG: kva:Kvar_0181 0. glycyl-tRNA synthetase, beta subunit K01879; Psort location: Cytoplasmic, score: 9.97. (689 aa) |
| | glyQ | KEGG: enc:ECL_00207 1.5e-164 glycyl-tRNA synthetase subunit alpha; K01878 glycyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 9.97. (303 aa) |
| | hypA | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (120 aa) |
| | EPF13032.1 | Hydrogenase accessory protein HypB; KEGG: reh:H16_A1087 2.0e-10 ureG; UreA amidohydrolase (urease) regulatory and maturation protein UreG K03189; Psort location: Cytoplasmic, score: 9.97. (287 aa) |
| | EPF13033.1 | Hydrogenase assembly chaperone HypC/HupF. (86 aa) |
| | EPF13034.1 | Hydrogenase expression/formation protein HypD; Psort location: Cytoplasmic, score: 8.96; Belongs to the HypD family. (373 aa) |
| | EPF13035.1 | KEGG: ddd:Dda3937_01823 3.1e-127 hypE, hydB; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein K04655; Psort location: Cytoplasmic, score: 8.96. (336 aa) |
| | rsmG | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (207 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (629 aa) |
| | trmH | RNA methyltransferase, TrmH family; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (218 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa) |
| | EPF12605.1 | TIGR00255 family protein; KEGG: isc:IscW_ISCW021220 8.8e-05 ecotropic viral integration site, putative; Psort location: Cytoplasmic, score: 9.97. (287 aa) |
| | rph | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (211 aa) |
| | rpmB | Ribosomal protein L28; KEGG: apb:SAR116_1905 8.8e-11 LSU ribosomal protein L28P K02902; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | rpmG | Ribosomal protein L33; KEGG: apb:SAR116_0619 1.1e-14 ribosomal protein L33 K02913; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | trmL | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (157 aa) |
| | rpmE | Ribosomal protein L31; Binds the 23S rRNA. (71 aa) |
| | trmA | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (366 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
