10 items (Leishmania infantum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LINJ_26_2730	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (267 aa)
	LINJ_33_2470	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (489 aa)
	LINJ_10_1030	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (533 aa)
	LINJ.12.0001	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (301 aa)
	LINJ_23_1270	Uncharacterized protein. (449 aa)
	LINJ_27_1090	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (669 aa)
	LINJ_30_1910	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (498 aa)
	LINJ_30_1920	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (499 aa)
	LINJ_32_3460	Glucosamine-6-phosphate isomerase. (279 aa)
	LinJ36.0740	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (375 aa)

Your Current Organism:

Leishmania infantum

NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LINJ.12.0001	LINJ_10_1030	A4HV45	A4HUK8	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ.12.0001	LINJ_27_1090	A4HV45	A4I2S1	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ_10_1030	LINJ.12.0001	A4HUK8	A4HV45	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ_10_1030	LINJ_27_1090	A4HUK8	A4I2S1	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ_27_1090	LINJ.12.0001	A4I2S1	A4HV45	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ_27_1090	LINJ_10_1030	A4I2S1	A4HUK8	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.999
LINJ_30_1910	LINJ_30_1920	A4I5L8	A4I5L9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.901
LINJ_30_1910	LINJ_33_2470	A4I5L8	E9AHQ2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904
LINJ_30_1920	LINJ_30_1910	A4I5L9	A4I5L8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.901
LINJ_30_1920	LINJ_33_2470	A4I5L9	E9AHQ2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904
LINJ_33_2470	LINJ_30_1910	E9AHQ2	A4I5L8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904
LINJ_33_2470	LINJ_30_1920	E9AHQ2	A4I5L9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904