36 items (Leishmania infantum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LINJ_33_2880	Putative translation initiation factor IF-2. (817 aa)
	LINJ_34_0370	Putative eukaryotic translation initiation factor 5. (378 aa)
	LINJ_34_1910	Putative eukaryotic translation initiation factor 2-alpha kinase. (1467 aa)
	LINJ_36_7320	Putative eukaryotic translation initiation factor 3 subunit 8. (731 aa)
	LINJ_36_0650	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (214 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (249 aa)
	LINJ_36_0270	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (544 aa)
	LINJ_36_4070	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (356 aa)
	eIF5A	Eukaryotic translation initiation factor 5A. (166 aa)
	LinJ01.0780	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (403 aa)
	LINJ_03_0960	Putative elongation initiation factor 2 alpha subunit. (413 aa)
	LINJ_08_0570	Translation initiation factor-like protein. (345 aa)
	LINJ_09_1130	Putative eukaryotic translation initiation factor 2 subunit. (479 aa)
	LINJ_09_1140	Putative translation initiation factor EIF-2B gamma subunit. (601 aa)
	LINJ_10_1030	Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (533 aa)
	LINJ.12.0001	Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (301 aa)
	LINJ_15_0060	Uncharacterized protein. (1016 aa)
	LINJ_15_1340	Uncharacterized protein. (1455 aa)
	LINJ_16_0150	Putative eukaryotic translation initiation factor 1A. (168 aa)
	LINJ_16_0690	Uncharacterized protein. (551 aa)
	EIF4G3	Putative eukaryotic translation initiation factor 4 gamma. (635 aa)
	LINJ_17_1390	Putative translation initiation factor. (709 aa)
	LINJ_19_1430	Transcription initiation factor-like protein (TFIID-like protein). (293 aa)
	LINJ_19_1520	Eukaryotic translation initiation factor-like protein; Belongs to the eukaryotic initiation factor 4E family. (281 aa)
	LINJ_22_1060	Putative translation initiation factor IF-2. (775 aa)
	LINJ_24_1380	Putative translation initiation factor IF-2. (891 aa)
	EIF5A2	Putative eukaryotic initiation factor 5a. (257 aa)
	LINJ_26_0230	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (182 aa)
	LINJ_27_1090	Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (669 aa)
	LINJ_27_1520	Putative eukaryotic translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family. (213 aa)
	LINJ_28_2460	Uncharacterized protein. (836 aa)
	LINJ_28_2480	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (405 aa)
	LINJ_28_2690	Putative eukaryotic translation initiation factor; Belongs to the eukaryotic initiation factor 4E family. (349 aa)
	LINJ_30_0460	Putative eukaryotic translation initiation factor 4e; Belongs to the eukaryotic initiation factor 4E family. (308 aa)
	LINJ_30_3080	Eukaryotic translation initiation factor 3 subunit 7-like protein; Belongs to the eIF-3 subunit D family. (531 aa)
	LINJ_32_2330	Uncharacterized protein. (233 aa)

Your Current Organism:

Leishmania infantum

NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4G3	LINJ_03_0960	A4HX58	A4HRY4	Putative eukaryotic translation initiation factor 4 gamma.	Putative elongation initiation factor 2 alpha subunit.	0.574
EIF4G3	LINJ_08_0570	A4HX58	A4HTK4	Putative eukaryotic translation initiation factor 4 gamma.	Translation initiation factor-like protein.	0.493
EIF4G3	LINJ_17_1390	A4HX58	A4HXK6	Putative eukaryotic translation initiation factor 4 gamma.	Putative translation initiation factor.	0.496
EIF4G3	LINJ_19_1520	A4HX58	A4HYH8	Putative eukaryotic translation initiation factor 4 gamma.	Eukaryotic translation initiation factor-like protein; Belongs to the eukaryotic initiation factor 4E family.	0.546
EIF4G3	LINJ_27_1520	A4HX58	A4I2V4	Putative eukaryotic translation initiation factor 4 gamma.	Putative eukaryotic translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family.	0.804
EIF4G3	LINJ_28_2480	A4HX58	A4I3W2	Putative eukaryotic translation initiation factor 4 gamma.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.500
EIF4G3	LINJ_28_2690	A4HX58	A4I3Y2	Putative eukaryotic translation initiation factor 4 gamma.	Putative eukaryotic translation initiation factor; Belongs to the eukaryotic initiation factor 4E family.	0.546
EIF4G3	LINJ_30_0460	A4HX58	A4I573	Putative eukaryotic translation initiation factor 4 gamma.	Putative eukaryotic translation initiation factor 4e; Belongs to the eukaryotic initiation factor 4E family.	0.546
EIF4G3	LINJ_30_3080	A4HX58	A4I5Y5	Putative eukaryotic translation initiation factor 4 gamma.	Eukaryotic translation initiation factor 3 subunit 7-like protein; Belongs to the eIF-3 subunit D family.	0.500
EIF4G3	LINJ_32_2330	A4HX58	A4I841	Putative eukaryotic translation initiation factor 4 gamma.	Uncharacterized protein.	0.446
EIF4G3	LINJ_34_0370	A4HX58	A4I9K5	Putative eukaryotic translation initiation factor 4 gamma.	Putative eukaryotic translation initiation factor 5.	0.652
EIF4G3	LINJ_36_0270	A4HX58	A4ICW2	Putative eukaryotic translation initiation factor 4 gamma.	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.498
EIF4G3	LINJ_36_4070	A4HX58	A4ID08	Putative eukaryotic translation initiation factor 4 gamma.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.446
EIF4G3	LINJ_36_7320	A4HX58	A4ICD8	Putative eukaryotic translation initiation factor 4 gamma.	Putative eukaryotic translation initiation factor 3 subunit 8.	0.599
EIF4G3	LinJ01.0780	A4HX58	A4HRK0	Putative eukaryotic translation initiation factor 4 gamma.	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.967
EIF5A2	EIF6	A4I1B5	A4ICP5	Putative eukaryotic initiation factor 5a.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.701
EIF5A2	LINJ_03_0960	A4I1B5	A4HRY4	Putative eukaryotic initiation factor 5a.	Putative elongation initiation factor 2 alpha subunit.	0.539
EIF5A2	LINJ_09_1130	A4I1B5	A4HU29	Putative eukaryotic initiation factor 5a.	Putative eukaryotic translation initiation factor 2 subunit.	0.526
EIF5A2	LINJ_09_1140	A4I1B5	A4HU30	Putative eukaryotic initiation factor 5a.	Putative translation initiation factor EIF-2B gamma subunit.	0.526
EIF5A2	LINJ_16_0150	A4I1B5	A4HWR3	Putative eukaryotic initiation factor 5a.	Putative eukaryotic translation initiation factor 1A.	0.815