STRINGSTRING
LINJ_36_0270 LINJ_36_0270 LINJ_28_2090 LINJ_28_2090 LINJ_28_0420 LINJ_28_0420 LINJ_27_1520 LINJ_27_1520 LINJ_27_1230 LINJ_27_1230 LINJ_27_1090 LINJ_27_1090 LINJ_26_0230 LINJ_26_0230 LINJ_25_2160 LINJ_25_2160 EIF5A2 EIF5A2 LINJ_28_2480 LINJ_28_2480 LINJ_28_2690 LINJ_28_2690 LINJ_29_0060 LINJ_29_0060 LinJ29.0880 LinJ29.0880 LINJ_30_0460 LINJ_30_0460 LINJ_30_3080 LINJ_30_3080 LINJ_30_3170 LINJ_30_3170 LINJ_30_3290 LINJ_30_3290 LINJ_32_1360 LINJ_32_1360 LINJ_32_2330 LINJ_32_2330 LINJ_33_1630 LINJ_33_1630 LINJ_33_2880 LINJ_33_2880 LINJ_33_2930 LINJ_33_2930 LINJ_33_2950 LINJ_33_2950 LINJ_34_0370 LINJ_34_0370 LinJ34.0590 LinJ34.0590 LINJ_34_0880 LINJ_34_0880 LINJ_34_0870 LINJ_34_0870 LINJ_34_1910 LINJ_34_1910 LINJ_34_2700 LINJ_34_2700 LINJ_35_4220 LINJ_35_4220 LINJ_36_7320 LINJ_36_7320 EIF6 EIF6 LINJ_36_0650 LINJ_36_0650 MEFG MEFG LINJ_21_0890 LINJ_21_0890 EF2-1 EF2-1 LINJ_36_4070 LINJ_36_4070 LINJ_36_1490 LINJ_36_1490 LINJ_36_4760 LINJ_36_4760 LINJ_36_4770 LINJ_36_4770 ILERS ILERS LINJ_17_0110 LINJ_17_0110 LINJ_17_0180 LINJ_17_0180 LINJ_18_0740 LINJ_18_0740 LINJ_24_0190 LINJ_24_0190 LINJ_24_0200 LINJ_24_0200 eIF5A eIF5A LINJ_25_0130 LINJ_25_0130 LINJ_24_1380 LINJ_24_1380 LINJ_23_0340 LINJ_23_0340 LINJ_22_1390 LINJ_22_1390 LINJ_22_1060 LINJ_22_1060 LINJ_28_2460 LINJ_28_2460 LinJ01.0780 LinJ01.0780 LINJ_03_0690 LINJ_03_0690 LINJ_03_0960 LINJ_03_0960 LINJ_04_0820 LINJ_04_0820 LINJ_08_0050 LINJ_08_0050 LINJ_08_0570 LINJ_08_0570 LINJ_09_1000 LINJ_09_1000 EF1G EF1G EF1G-2 EF1G-2 LINJ_09_1130 LINJ_09_1130 LINJ_09_1140 LINJ_09_1140 LINJ_10_1030 LINJ_10_1030 LINJ.12.0001 LINJ.12.0001 LINJ_13_1000 LINJ_13_1000 LINJ_15_0060 LINJ_15_0060 LINJ_15_1340 LINJ_15_1340 LINJ_15_1490 LINJ_15_1490 LINJ_16_0150 LINJ_16_0150 LINJ_16_0690 LINJ_16_0690 EIF4G3 EIF4G3 LINJ_17_0090 LINJ_17_0090 LINJ_17_1390 LINJ_17_1390 LINJ_19_1430 LINJ_19_1430 LINJ_19_1520 LINJ_19_1520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LINJ_36_0270Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (544 aa)
LINJ_28_2090Elongation factor G2-like protein. (763 aa)
LINJ_28_0420Uncharacterized protein. (216 aa)
LINJ_27_1520Putative eukaryotic translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family. (213 aa)
LINJ_27_1230Putative arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (692 aa)
LINJ_27_1090Putative translation initiation factor eIF2B subunit-like protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (669 aa)
LINJ_26_0230Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (182 aa)
LINJ_25_2160Elongation factor 2-like protein. (887 aa)
EIF5A2Putative eukaryotic initiation factor 5a. (257 aa)
LINJ_28_2480Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (405 aa)
LINJ_28_2690Putative eukaryotic translation initiation factor; Belongs to the eukaryotic initiation factor 4E family. (349 aa)
LINJ_29_0060Putative tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (396 aa)
LinJ29.0880Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. (276 aa)
LINJ_30_0460Putative eukaryotic translation initiation factor 4e; Belongs to the eukaryotic initiation factor 4E family. (308 aa)
LINJ_30_3080Eukaryotic translation initiation factor 3 subunit 7-like protein; Belongs to the eIF-3 subunit D family. (531 aa)
LINJ_30_3170Putative valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (967 aa)
LINJ_30_3290Putative glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (594 aa)
LINJ_32_1360Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (271 aa)
LINJ_32_2330Uncharacterized protein. (233 aa)
LINJ_33_1630Putative elongation factor 1-gamma; Belongs to the GST superfamily. (220 aa)
LINJ_33_2880Putative translation initiation factor IF-2. (817 aa)
LINJ_33_2930Putative GTP-binding protein. (842 aa)
LINJ_33_2950Transcription elongation factor-like protein. (473 aa)
LINJ_34_0370Putative eukaryotic translation initiation factor 5. (378 aa)
LinJ34.0590Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (834 aa)
LINJ_34_0880Putative 25 Kd elongation factor 1-beta. (77 aa)
LINJ_34_0870Putative translation elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family. (239 aa)
LINJ_34_1910Putative eukaryotic translation initiation factor 2-alpha kinase. (1467 aa)
LINJ_34_2700Putative selenocysteine-specific elongation factor. (678 aa)
LINJ_35_4220Putative elongation factor 1-alpha. (646 aa)
LINJ_36_7320Putative eukaryotic translation initiation factor 3 subunit 8. (731 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (249 aa)
LINJ_36_0650Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (214 aa)
MEFGElongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (746 aa)
LINJ_21_0890Putative methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (747 aa)
EF2-1Elongation factor 2. (845 aa)
LINJ_36_4070Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (356 aa)
LINJ_36_1490Putative translation elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family. (211 aa)
LINJ_36_4760Elongation factor-2 kinase-like protein. (369 aa)
LINJ_36_4770Related to elongation factor-2 kinase efk-1b isoform-like protein. (1141 aa)
ILERSPutative isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1100 aa)
LINJ_17_0110Elongation factor 1-alpha. (503 aa)
LINJ_17_0180Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (449 aa)
LINJ_18_0740Putative elongation factor Tu. (466 aa)
LINJ_24_0190Transcription elongation factor-like protein. (235 aa)
LINJ_24_0200Putative transcription elongation factor. (333 aa)
eIF5AEukaryotic translation initiation factor 5A. (166 aa)
LINJ_25_0130Putative elongation factor. (634 aa)
LINJ_24_1380Putative translation initiation factor IF-2. (891 aa)
LINJ_23_0340Putative tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (412 aa)
LINJ_22_1390Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (962 aa)
LINJ_22_1060Putative translation initiation factor IF-2. (775 aa)
LINJ_28_2460Uncharacterized protein. (836 aa)
LinJ01.0780Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (403 aa)
LINJ_03_0690Uncharacterized protein. (228 aa)
LINJ_03_0960Putative elongation initiation factor 2 alpha subunit. (413 aa)
LINJ_04_0820Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (393 aa)
LINJ_08_0050Uncharacterized protein. (75 aa)
LINJ_08_0570Translation initiation factor-like protein. (345 aa)
LINJ_09_1000O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (595 aa)
EF1GElongation factor-1 gamma. (453 aa)
EF1G-2Elongation factor-1 gamma. (405 aa)
LINJ_09_1130Putative eukaryotic translation initiation factor 2 subunit. (479 aa)
LINJ_09_1140Putative translation initiation factor EIF-2B gamma subunit. (601 aa)
LINJ_10_1030Translation initiation factor eif-2b beta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (533 aa)
LINJ.12.0001Putative translation initiation factor EIF-2b alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (301 aa)
LINJ_13_1000Putative leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1075 aa)
LINJ_15_0060Uncharacterized protein. (1016 aa)
LINJ_15_1340Uncharacterized protein. (1455 aa)
LINJ_15_1490Putative glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (570 aa)
LINJ_16_0150Putative eukaryotic translation initiation factor 1A. (168 aa)
LINJ_16_0690Uncharacterized protein. (551 aa)
EIF4G3Putative eukaryotic translation initiation factor 4 gamma. (635 aa)
LINJ_17_0090Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (449 aa)
LINJ_17_1390Putative translation initiation factor. (709 aa)
LINJ_19_1430Transcription initiation factor-like protein (TFIID-like protein). (293 aa)
LINJ_19_1520Eukaryotic translation initiation factor-like protein; Belongs to the eukaryotic initiation factor 4E family. (281 aa)
Your Current Organism:
Leishmania infantum
NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum
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