(41 nodes) Toll Like Receptor TLR6:TLR2 Cascade network (Leishmania infantum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LINJ_21_1500	Uncharacterized protein. (498 aa)
	LINJ_05_0650	Uncharacterized protein. (867 aa)
	LINJ_05_0220	Dual specificity phosphatase-like protein. (671 aa)
	LINJ_05_0150	Uncharacterized protein. (441 aa)
	LINJ_04_1220	Uncharacterized protein. (187 aa)
	LINJ_04_0840	Tyrosine phospatase-like protein. (692 aa)
	LINJ_04_0550	Putative tyrosine phosphatase. (309 aa)
	LINJ_22_0120	Putative phosphoinositide phosphatase. (258 aa)
	LINJ_21_0240	Uncharacterized protein. (1475 aa)
	LINJ_21_0220	Uncharacterized protein. (747 aa)
	LINJ_21_0500	Ubiquitin-conjugating enzyme-like protein. (270 aa)
	LINJ_20_0720	Putative serine/threonine protein phosphatase 2A regulatory subunit. (599 aa)
	LINJ_18_0670	Uncharacterized protein. (711 aa)
	LINJ_09_1610	Uncharacterized protein. (338 aa)
	LINJ_11_0890	Uncharacterized protein. (1010 aa)
	LINJ_17_0640	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein. (318 aa)
	LINJ_16_0720	Uncharacterized protein. (529 aa)
	LINJ_15_0980	Uncharacterized protein. (831 aa)
	LINJ_14_1350	Putative ubiquitin/ribosomal protein S27a. (152 aa)
	LINJ_13_0800	Uncharacterized protein. (821 aa)
	LINJ_24_1630	Uncharacterized protein. (600 aa)
	LINJ_24_0180	Uncharacterized protein. (813 aa)
	LINJ.12.0650	Uncharacterized protein. (850 aa)
	LINJ_36_4440	Uncharacterized protein. (1123 aa)
	LINJ_36_5510	Uncharacterized protein. (1052 aa)
	LINJ_36_0660	Putative ubiquitin/ribosomal protein S27a. (152 aa)
	LINJ_34_1400	Uncharacterized protein. (719 aa)
	LINJ_33_2990	Uncharacterized protein. (258 aa)
	LINJ_32_3360	Uncharacterized protein. (817 aa)
	LINJ_32_1070	Uncharacterized protein. (423 aa)
	LINJ_32_0480	Uncharacterized protein. (942 aa)
	LINJ_30_0150	Putative leucine-rich repeat protein. (216 aa)
	LINJ_29_2920	Ribonuclease inhibitor-like protein. (736 aa)
	LINJ_28_2120	Uncharacterized protein. (753 aa)
	LINJ_28_0170	Putative phopshatase. (424 aa)
	LINJ_27_1200	Uncharacterized protein. (396 aa)
	LINJ_26_0490	Uncharacterized protein. (429 aa)
	LINJ_25_1360	Serine/threonine-protein phosphatase. (317 aa)
	LINJ_25_0580	Uncharacterized protein. (340 aa)
	LINJ_23_0170	Uncharacterized protein. (366 aa)
	LINJ_22_1450	Putative ser/thr protein phosphatase. (811 aa)

Your Current Organism:

Leishmania infantum

NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LINJ_04_0840	LINJ_25_0580	A4HS81	A4I198	Tyrosine phospatase-like protein.	Uncharacterized protein.	0.542
LINJ_05_0150	LINJ_23_0170	A4HSD0	A4I053	Uncharacterized protein.	Uncharacterized protein.	0.431
LINJ_09_1610	LINJ_23_0170	A4HU75	A4I053	Uncharacterized protein.	Uncharacterized protein.	0.442
LINJ_09_1610	LINJ_30_0150	A4HU75	A4I510	Uncharacterized protein.	Putative leucine-rich repeat protein.	0.418
LINJ_14_1350	LINJ_21_0500	A4HW73	A4HZ43	Putative ubiquitin/ribosomal protein S27a.	Ubiquitin-conjugating enzyme-like protein.	0.827
LINJ_14_1350	LINJ_36_0660	A4HW73	A4ICS4	Putative ubiquitin/ribosomal protein S27a.	Putative ubiquitin/ribosomal protein S27a.	0.900
LINJ_15_0980	LINJ_17_0640	A4HWJ0	A4HXD2	Uncharacterized protein.	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	0.624
LINJ_15_0980	LINJ_22_1450	A4HWJ0	A4I019	Uncharacterized protein.	Putative ser/thr protein phosphatase.	0.624
LINJ_15_0980	LINJ_25_1360	A4HWJ0	A4I1H6	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.624
LINJ_17_0640	LINJ_15_0980	A4HXD2	A4HWJ0	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	Uncharacterized protein.	0.624
LINJ_17_0640	LINJ_18_0670	A4HXD2	A4HXU2	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	Uncharacterized protein.	0.624
LINJ_17_0640	LINJ_20_0720	A4HXD2	A4HYP6	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	Putative serine/threonine protein phosphatase 2A regulatory subunit.	0.624
LINJ_17_0640	LINJ_24_0180	A4HXD2	E9AH30	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	Uncharacterized protein.	0.624
LINJ_17_0640	LINJ_36_5510	A4HXD2	A4IDU9	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	Uncharacterized protein.	0.624
LINJ_18_0670	LINJ_17_0640	A4HXU2	A4HXD2	Uncharacterized protein.	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	0.624
LINJ_18_0670	LINJ_22_1450	A4HXU2	A4I019	Uncharacterized protein.	Putative ser/thr protein phosphatase.	0.624
LINJ_18_0670	LINJ_25_1360	A4HXU2	A4I1H6	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.624
LINJ_20_0720	LINJ_17_0640	A4HYP6	A4HXD2	Putative serine/threonine protein phosphatase 2A regulatory subunit.	Bis(5'-nucleosyl)-tetraphosphatase,symmetrical-like protein.	0.624
LINJ_20_0720	LINJ_22_1450	A4HYP6	A4I019	Putative serine/threonine protein phosphatase 2A regulatory subunit.	Putative ser/thr protein phosphatase.	0.624
LINJ_20_0720	LINJ_25_1360	A4HYP6	A4I1H6	Putative serine/threonine protein phosphatase 2A regulatory subunit.	Serine/threonine-protein phosphatase.	0.960